Adrenergic modulation of astroglial phospholipase D activity and cell proliferation

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

1987 • 3,773 citations

Glucosylation of Rho proteins by Clostridium difficile toxin B

1995 • 1,025 citations

Neurotransmitters as growth regulatory signals: role of receptors and second messengers

1993 • 806 citations

Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells

1996 • 447 citations

Phospholipase D: enzymology, mechanisms of regulation, and function

1997 • 405 citations

G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity.

1991 • 321 citations

Phosphoinositide-specific phospholipase C and mitogenic signaling

1995 • 286 citations

Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes

1989 • 254 citations

Characterization of the glycogenolysis elicited by vasoactive intestinal peptide, noradrenaline and adenosine in primary cultures of mouse cerebral cortical astrocytes

1991 • 231 citations

Stimulation of actin stress fibre formation mediated by activation of phospholipase D

1996 • 215 citations

Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A.

1995 • 193 citations

Acetylcholine as a mitogen: muscarinic receptor-mediated proliferation of rat astrocytes and human astrocytoma cells

1996 • 182 citations

Messenger functions of phosphatidic acid

1996 • 177 citations

Phosphatidic acid formation by phospholipase D is required for transport from the endoplasmic reticulum to the Golgi complex

1997 • 174 citations

Inhibitors of protein kinase C

1994 • 160 citations

A role for phospholipase D in control of mitoqenesis

1994 • 137 citations

Receptor-mediated inositol phospholipid hydrolysis in astrocytes

1986 • 112 citations

Role of Phospholipase D Activation in Nervous System Physiology and Pathophysiology

1995 • 107 citations

Effects of Neurotransmitters on Astrocyte Glycogen Stores In Vitro

1988 • 99 citations

Evidence for ADP‐Ribosylation‐Factor‐Mediated Activation of Phospholipase D by m3 Muscarinic Acetylcholine Receptor

1995 • 94 citations

Excitatory Amino Acids Stimulate Inositol Phospholipid Hydrolysis and Reduce Proliferation in Cultured Astrocytes

1990 • 84 citations

Alpha 1-adrenergic receptor-mediated activation of phospholipase D in rat cerebral cortex.

1992 • 69 citations

Regulation of phospholipase D by tyrosine kinases

1996 • 64 citations

Comparison of human α1-adrenoceptor subtype coupling to protein kinase C activation and related signalling pathways

1998 • 60 citations

Alpha-1A adrenergic receptor stimulation with phenylephrine promotes arachidonic acid release by activation of phospholipase D in rat-1 fibroblasts: inhibition by protein kinase A.

1998 • 58 citations

A protein kinase C inhibitor, staurosporine, activates phospholipase D via a pertussis toxin-sensitive GTP-binding protein in rabbit peritoneal neutrophils.

1992 • 49 citations

Proliferation of human and mouse astrocytes in vitro: signalling through the protein kinase C pathway

1992 • 47 citations

Signal Transduction Mechanisms in Glial Cells (Part 1 of 2)

1995 • 45 citations

Phospholipase D-induced phosphatidate production in intact small arteries during noradrenaline stimulation: involvement of both G-protein and tyrosine-phosphorylation-linked pathways

1995 • 38 citations

Stimulation of Phospholipase D via α₁-Adrenergic Receptors in Madin-Darby Canine Kidney Cells is Independent of PKCα and -ε Activation

1998 • 38 citations

Utilization of alcohols by plant and mammalian phospholipase D

1997 • 37 citations

Phosphatidic acid promotes phosphoinositide metabolism and DNA synthesis in cultured cortical astrocytes

1994 • 35 citations

A tyrosine kinase regulates α-adrenoceptor-stimulated contraction and phospholipase D activation in the rat aorta

1996 • 34 citations

Receptor‐mediated phospholipase D activity in primary astroglial cultures

1993 • 23 citations

Primary Alcohols and Phosphatidylcholine Metabolism in Rat Brain Synaptosomal Membranes via Phospholipase D

1996 • 23 citations

Differential regulation of phospholipases C and D by phorbol esters and the physiological activators carbachol and glutamate in astrocytes from chicken embryo cerebrum and cerebellum

1995 • 22 citations

Adrenergic activation of phospholipase D in primary rat astrocytes

1996 • 16 citations

Endothelin Stimulates Phospholipase D in Striatal Astrocytes

1997 • 15 citations

Brefeldin A Inhibits Antigen- or Calcium Ionophore-Mediated but not PMA-Induced Phospholipase D Activation in Rat Basophilic Leukemia (RBL-21-13) Cells

1996 • 12 citations