Loss of fibroblast growth factor receptors is necessary for terminal differentiation of embryonic limb muscle

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro.

1982 • 932 citations

fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation.

1994 • 784 citations

bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out.

1994 • 686 citations

Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

1992 • 676 citations

Two myogenic lineages within the developing somite

1992 • 570 citations

Type beta transforming growth factor is an inhibitor of myogenic differentiation.

1986 • 559 citations

Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse

1992 • 552 citations

Limb-somite relationship: origin of the limb musculature

1977 • 528 citations

Experimental analysis of the origin of the wing musculature in avian embryos

1977 • 520 citations

Growth factor control of skeletal muscle differentiation: commitment to terminal differentiation occurs in G1 phase and is repressed by fibroblast growth factor.

1987 • 480 citations

FGF-2: Apical Ectodermal Ridge Growth Signal for Chick Limb Development

1994 • 470 citations

Interplay between proliferation and differentiation within the myogenic lineage

1992 • 424 citations

Regulation of myogenic differentiation by type beta transforming growth factor.

1986 • 408 citations

Retroviral analysis of cardiac morphogenesis: discontinuous formation of coronary vessels.

1992 • 386 citations

Basic fibroblast growth factor fused to a signal peptide transforms cells

1988 • 379 citations

“Spontaneous” differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II

1991 • 365 citations

Myogenic cell lineages

1992 • 360 citations

FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains

1992 • 333 citations

The Encephalomyocarditis Virus Internal Ribosome Entry Site Allows Efficient Coexpression of Two Genes from a Recombinant Provirus in Cultured Cells and in Embryos

1991 • 333 citations

Diffusion-mediated control of myoblast fusion

1971 • 283 citations

A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor.

1992 • 272 citations

Expression of the fibroblast growth factor-5 gene in the mouse embryo

1991 • 264 citations

Transforming growth factor-beta. A very potent inhibitor of myoblast differentiation, identical to the differentiation inhibitor secreted by Buffalo rat liver cells.

1986 • 247 citations

Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate.

1992 • 241 citations

Mesoderm induction by activin requires FGF-mediated intracellular signals

1994 • 225 citations

Activin-mediated mesoderm induction requires FGF

1994 • 208 citations

Cell surface fibroblast growth factor and epidermal growth factor receptors are permanently lost during skeletal muscle terminal differentiation in culture.

1988 • 197 citations

Nuclear and cytoplasmic localization of basic fibroblast growth factor in astrocytes and CA2 hippocampal neurons

1992 • 192 citations

Fibroblast growth factor receptor is required for in vivo cardiac myocyte proliferation at early embryonic stages of heart development.

1995 • 186 citations

Role of myogenin in myoblast differentiation and its regulation by fibroblast growth factor.

1990 • 177 citations

Developmental changes preceding cell fusion during muscle differentiation in vitro

1971 • 176 citations

Basic fibroblast growth factor in the chick embryo: immunolocalization to striated muscle cells and their precursors.

1989 • 172 citations

Clonal analysis of vertebrate myogenesis

1974 • 169 citations

Control by fibroblast growth factor of differentiation in the BC3H1 muscle cell line.

1985 • 166 citations

High mutation rate of a spleen necrosis virus-based retrovirus vector.

1986 • 157 citations

Expression of the Fgf6 gene is restricted to developing skeletal muscle in the mouse embryo

1993 • 130 citations

Heparan sulfate proteoglycan and FGF receptor target basic FGF to different intracellular destinations

1993 • 130 citations

The migration of myogenic cells from the somites into the leg region of avian embryos

1979 • 113 citations

In vivo analysis of a new lacZ retrovirus vector suitable for cell lineage marking in avian and other species*1

1991 • 113 citations

Clonal analysis of vertebrate myogenesis

1988 • 108 citations

An Additional Limb Can Be Induced from the Flank of the Chick Embryo by FGF4

1995 • 105 citations

Differential transforming abilities of non-secreted and secreted forms of human fibroblast growth factor-1.

1993 • 104 citations

The mRNAs encoding acidic FGF, basic FGF and FGF receptor are coordinately downregulated during myogenic differentiation

1991 • 104 citations

Different Members of the Fibroblast Growth Factor Receptor Family Are Specific to Distinct Cell Types in the Developing Chicken Embryo

1993 • 104 citations

Clonal analysis of cardiac morphogenesis in the chicken embryo using a replication‐defective retrovirus. III: Polyclonal origin of adjacent ventricular myocytes

1992 • 102 citations

Fibroblast growth factor receptor levels decrease during chick embryogenesis.

1990 • 99 citations

Transforming growth factor beta induces myoblast differentiation in the presence of mitogens.

1992 • 99 citations

Myosin light-chain expression during avian muscle development

1983 • 98 citations

Fibroblast growth factor levels in the whole embryo and limb bud during chick development

1988 • 97 citations

Fibroblast growth factor-2 (FGF-2) in the nucleus: Translocation process and targets

1994 • 95 citations

Inhibition of Precardiac Mesoderm Cell Proliferation by Antisense Oligodeoxynucleotide Complementary to Fibroblast Growth Factor-2 (FGF-2)

1993 • 89 citations

Initial steps of myogenesis in somites are independent of influence from axial structures

1994 • 87 citations

Inhibition of myogenic differentiation in myoblasts expressing a truncated type II TGF-β receptor

1994 • 86 citations

Myogenic growth factor present in skeletal muscle is purified by heparin-affinity chromatography.

1985 • 86 citations

Temporal and quantitative analysis of myogenic regulatory and growth factor gene expression in the developing mouse embryo

1992 • 78 citations

FGF-mediated aspects of skeletal muscle growth and differentiation are controlled by a high affinity receptor, FGFR1

1992 • 72 citations

Fibroblast Growth Factor Inhibits Insulin-Like Growth Factor-II (IGF-II) Gene Expression and Increases IGF-I Receptor Abundance in BC3H-1 Muscle Cells

1991 • 71 citations

Intracrine regulation at the nucleus–a further mechanism of growth factor activity?

1990 • 71 citations

Retroviral Targeting of FGF and FGFR in Cardiomyocytes and Coronary Vascular Cells during Heart Development^a

1995 • 66 citations

Experimental analysis of the mechanisms of somite morphogenesis

1974 • 61 citations

The migration of myogenic cells from the somites at the wing level in avian embryos

1987 • 59 citations

Embryonic signals for skeletal myogenesis: arriving at the beginning

1993 • 44 citations

Commitment and differentiation of cardiac myocytes

1992 • 44 citations

FGF Can Induce Outgrowth of Somatic Mesoderm both Inside and Outside of Limb-Forming Regions

1995 • 42 citations

Mesoderm induction by activin requires FGF-mediated intracellular signals

1994 • 41 citations

Antisense suppression of skeletal muscle myosin light chain-1 biosynthesis impairs myofibrillogenesis in cultured myotubes

1995 • 18 citations

Growth factor responsiveness: Role of MyoD and myogenin

1992 • 8 citations