Analysis of glucocorticoid unresponsive cell variants using a mouse glucocorticoid receptor complementary DNA clone.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

1985 • 1,851 citations

Isolation and Characterization of Full-Length cDNA Clones for Human α-, β-, and γ-Actin mRNAs: Skeletal but Not Cytoplasmic Actins Have an Amino-Terminal Cysteine that Is Subsequently Removed

1983 • 1,220 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

1983 • 933 citations

Mechanism of Action of the Female Sex Hormones

1972 • 763 citations

Current Models of Steroid Hormone Action: A Critique

1976 • 707 citations

Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region

1983 • 700 citations

Steroid Receptors: Elements for Modulation of Eukaryotic Transcription

1976 • 688 citations

Identification of procollagen mRNAs transferred to diazobenzyloxymethyl paper from formaldehyde agarose gels

1979 • 564 citations

Induction of tyrosine alpha-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line.

1966 • 484 citations

Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo.

1981 • 341 citations

Mechanisms of steroid resistance

1974 • 284 citations

Transcriptional regulation of mouse liver metallothionein-I gene by glucocorticoids

1981 • 284 citations

Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells

1984 • 278 citations

Genetic Approaches to Steroid Hormone Action

1976 • 203 citations

Structure of Mammalian Steroid Receptors: Evolving Concepts and Methodological Developments

1984 • 188 citations

Metallothionein mRNA induction in HeLa cells in response to zinc or dexamethasone is a primary induction response

1980 • 186 citations

Differentiated functions expressed by cultured mouse lymphoma cells. II. Theta antigen, surface immunoglobulin and a receptor for antibody on cells of a thymoma cell line.

1973 • 184 citations

Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains.

1982 • 178 citations

Isolation of lymphoma cell variants resistant to killing by glucocorticoids

1974 • 176 citations

Diploid and haploid states of the glucocorticoid receptor gene of mouse lymphoid cell lines

1977 • 170 citations

Receptors from Glucocorticoid-Sensitive Lymphoma Cells and Two Classes of Insensitive Clones: Physical and DNA-Binding Properties

1974 • 166 citations

Production of mouse mammary tumor virus by cultured cells in the absence and presence of hormones: Assay by molecular hybridization

1975 • 162 citations

A new mechanism for steroid unresponsiveness: Loss of nuclear binding activity of a steroid hormone receptor

1974 • 123 citations

Integration and transcription of mouse mammary tumor virus DNA in rat hepatoma cells.

1979 • 120 citations

Differentiated Functions Expressed by Cultured Mouse Lymphoma Cells

1973 • 117 citations

Immunochemical characterization of wild-type and variant glucocorticoid receptors by monoclonal antibodies.

1984 • 89 citations

Down-regulation of glucocorticoid receptors in mouse lymphoma cell variants.

1984 • 87 citations

Active domains in wild-type and mutant glucocorticoid receptors.

1982 • 78 citations

Photoaffinity labeling and partial proteolysis of wild-type and variant glucocorticoid receptors

1983 • 74 citations

Characterization of wild type and mutant glucocorticoid receptors from rat hepatoma and mouse lymphoma cells.

1985 • 64 citations

Isolation of glucocorticoid-unresponsive rat hepatoma cells by fluorescence-activated cell sorting

1980 • 63 citations

Glucorticoid resistance in murine lymphoma and thymoma lines.

1978 • 62 citations

Interaction of glucocorticoid receptors from lymphoid cell lines with their nuclear acceptor sites

1978 • 51 citations

Changes in hormone responsiveness of chick oviduct during primary stimulation with estrogen

1980 • 46 citations