Use of an in vivo model to determine the effects of interleukin-1 on cells at different stages in the osteoclast lineage

Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6

1992 • 1,437 citations

17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens.

1992 • 685 citations

IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release.

1990 • 493 citations

Actions of recombinant interleukin 1, interleukin 2, and interferon-gamma on bone resorption in vitro.

1986 • 484 citations

Interleukin-1 and tumor necrosis factor stimulate the formation of human osteoclastlike cells in vitro

1989 • 467 citations

Osteoblasts mediate interleukin 1 stimulation of bone resorption by rat osteoclasts.

1986 • 392 citations

Synergy of interleukin 1 and granulocyte colony-stimulating factor: in vivo stimulation of stem-cell recovery and hematopoietic regeneration following 5-fluorouracil treatment of mice.

1987 • 380 citations

Effects of Interleukin-1 on Bone Turnover in Normal Mice*

1989 • 366 citations

Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of bone.

1992 • 363 citations

Inhibition of osteoclast-like cell formation by bisphosphonates in long-term cultures of human bone marrow.

1989 • 363 citations

Bisphosphonates directly inhibit the bone resorption activity of isolated avian osteoclasts in vitro.

1990 • 322 citations

Perspectives: Interleukin-6: An osteotropic factor?

1992 • 283 citations

Interleukin 1 induces human marrow stromal cells in long-term culture to produce granulocyte colony-stimulating factor and macrophage colony- stimulating factor

1988 • 248 citations

Identification of Committed Mononuclear Precursors for Osteoclast-Like Cells Formed in Long Term Human Marrow Cultures*

1990 • 232 citations

Infusions of recombinant human interleukins 1 alpha and 1 beta cause hypercalcemia in normal mice.

1988 • 218 citations

Human interleukin-6 supports granulocytic differentiation of hematopoietic progenitor cells and acts synergistically with GM-CSF

1989 • 157 citations

Bisphosphonates--history and experimental basis.

1987 • 156 citations

Induction of colony stimulating factor in vivo by recombinant interleukin 1 alpha and recombinant tumor necrosis factor alpha 1.

1987 • 147 citations

Bisphosphonates in vitro specifically inhibit, among the hematopoietic series, the development of the mouse mononuclear phagocyte lineage

1990 • 97 citations

Atypical multinucleated cells form in long-term marrow cultures from patients with Paget's disease.

1990 • 86 citations

Interleukin-1 enhances murine granulopoiesis in vivo.

1988 • 68 citations

Abnormalities in osteoclast precursors and marrow accessory cells in Paget's disease.

1993 • 67 citations

Monocyte-conditioned medium and interleukin 1 induce granulocyte-macrophage colony-stimulating factor production in the adherent cell layer of murine bone marrow cultures.

1986 • 58 citations

Interleukin-1 in Combination with Transforming Growth Factor-α Produces Enhanced Bone Resorptionin Vitro*

1988 • 47 citations

In vivo effect of interleukin-1 alpha on hematopoiesis: role of colony- stimulating factor receptor modulation

1992 • 30 citations

Spontaneous release of interleukin-1 (IL-1) from medullary mononuclear cells of pagetic subjects

1989 • 23 citations

Purified murine granulocyte/macrophage progenitor cells express a high-affinity receptor for recombinant murine granulocyte/macrophage colony-stimulating factor.

1988 • 21 citations