Effects of phorbol ester on cell growth inhibition by transforming growth factor β 1 in human hepatoma cell lines

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Peptide growth factors are multifunctional

1988 • 835 citations

The transforming growth factor-β system, a complex pattern of cross-reactive ligands and receptors

1987 • 710 citations

A new alkaloid AM-2282 of Streptomyces origin taxonomy, fermentation, isolation and preliminary characterization.

1977 • 659 citations

Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium.

1986 • 559 citations

In vitro studies on the mode of action of the phorbol esters, potent tumor promoters: Part 1

1980 • 477 citations

Protein kinase C as the receptor for the phorbol ester tumor promoters: sixth Rhoads memorial award lecture.

1988 • 430 citations

Liberation of [3H]arachidonic acid and changes in cytosolic free calcium in fura-2-loaded human platelets stimulated by ionomycin and collagen

1986 • 292 citations

Transforming growth factor-beta is a strong and fast acting positive regulator of the level of type-1 plasminogen activator inhibitor mRNA in WI-38 human lung fibroblasts.

1987 • 247 citations

Cellular distribution of type I and type II receptors for transforming growth factor-beta.

1986 • 203 citations

A diacylglycerol analogue reduces neuronal calcium currents independently of protein kinase C activation

1989 • 190 citations

Serotonin secretion from human platelets may be modified by Ca2+-activated, phospholipid-dependent myosin phosphorylation.

1984 • 143 citations

[17] Identification of receptor for type-β transforming growth factor

1987 • 134 citations

N-(2-Aminoethyl)-5-isoquinolinesulfonamide, a newly synthesized protein kinase inhibitor, functions as a ligand in affinity chromatography. Purification of Ca2+-activated, phospholipid-dependent and other protein kinases.

1985 • 122 citations

Tumor promoters and cell transformation

1984 • 63 citations

Arachidonic acid release in rabbit neutrophils

1989 • 47 citations

Antiproliferative properties of phorbol ester tumour promoters

1985 • 43 citations

Demonstration of calcium-dependent phospholipase A2 activity in membrane preparation of rabbit neutrophils. Absence of activation by fMet-Leu-Phe, phorbol 12-myristate 13-acetate and A-kinase

1988 • 29 citations

Modulation of c‐myc Expression by Transforming Growth Factor β1 in Human Hepatoma Cell Lines

1990 • 12 citations

A Fluorescent Protein Kinase C Inhibitor: 1-(1-Hydroxy-5-isoquinolinylsulfonyl)piperazine

1988 • 8 citations

Effect of phorbol esters on the activity of purified transforming growth factors.

1986 • 5 citations