A single base change in the Shine-Dalgarno region of 16S rRNA of Escherichia coli affects translation of many proteins.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Experiments in molecular genetics

1972 • 28,260 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures

2013 • 5,819 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

The 3′-Terminal Sequence of Escherichia coli 16S Ribosomal RNA: Complementarity to Nonsense Triplets and Ribosome Binding Sites

1974 • 3,603 citations

Procedures in Nucleic Acid Research.

1967 • 2,043 citations

Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles

1983 • 1,256 citations

Procedures in nucleic acid research

1966 • 987 citations

Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template

1984 • 947 citations

Structure, Function, and Genetics of Ribosomes

1986 • 852 citations

Translational Initiation in Prokaryotes

1981 • 785 citations

How ribosomes select initiator regions in mRNA: base pair formation between the 3' terminus of 16S rRNA and the mRNA during initiation of protein synthesis in Escherichia coli.

1975 • 690 citations

Characterization of translational initiation sites inE. coli

1982 • 673 citations

[16] Plasmids of Escherichia coli as cloning vectors

1979 • 655 citations

THE GENETICS AND REGULATION OF HEAT-SHOCK PROTEINS

1984 • 648 citations

The UNC operon nucleotide sequence, regulation and structure of ATP-synthase

1984 • 519 citations

Oligonucleotide synthesis: A practical approach

1985 • 493 citations

Oligonucleotide synthesis : a practical approach

1984 • 491 citations

Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli

1981 • 476 citations

Electrophoretic characterization of bacterial polyribosomes in agarose-acrylamide composite gels

1969 • 433 citations

Nucleotide sequence of the ribosomal protein gene cluster adjacent to the gene for RNA polymerase subunit beta in Escherichia coli.

1979 • 350 citations

A role for mRNA secondary structure in the control of translation initiation

1982 • 344 citations

Specialized ribosome system: preferential translation of a single mRNA species by a subpopulation of mutated ribosomes in Escherichia coli.

1987 • 289 citations

Specific Inactivation of 16S Ribosomal RNA Induced by Colicin E3 In Vivo

1971 • 238 citations

The ribosome binding sites recognized by E. coli ribosomes have regions with signal character in both the leader and protein coding segments

1980 • 206 citations

Covalent crosslinking of tRNA1Val to 16S RNA at the ribosomal P site: identification of crosslinked residues.

1982 • 203 citations

Protection of specific sites in 16 S RNA from chemical modification by association of 30 S and 50 S ribosomes

1977 • 151 citations

Gene-protein index of Escherichia coli K-12

1983 • 151 citations

Feedback regulation of rRNA and tRNA synthesis and accumulation of free ribosomes after conditional expression of rRNA genes.

1985 • 148 citations

Recognition of messenger RNA during translational initiation in Escherichia coli

1984 • 124 citations

Binding of ribosomal protein S1 of Escherichia coli to the 3' end of 16S rRNA.

1975 • 121 citations

Sequence specificity in transcription and translation

1985 • 113 citations

Mutations of bacteriophage T7 that affect initiation of synthesis of the gene 0.3 protein

1978 • 109 citations

The sequence of metK, the structural gene for S-adenosylmethionine synthetase in Escherichia coli.

1984 • 108 citations

Increased translational fidelity caused by the antibiotic kasugamycin and ribosomal ambiguity in mutants harbouring the ksgA gene

1984 • 93 citations

Methionyl-tRNA synthetase from Escherichia coli. Primary structure of the active crystallised tryptic fragment.

1982 • 89 citations

The nucleotide sequence of theEscherichta coli fusgene, coding for elongation factor G

1984 • 88 citations

Inhibition of Qβ RNA 70S ribosome initiation complex formation by an oligonucleotide complementary to the 3′ terminal region of E. coli 16S ribosomal RNA

1978 • 75 citations

Portable Shine-Dalgarno Regions: A System for a Systematic Study of Defined Alterations of Nucleotide Sequences withinE. coliRibosome Binding Sites

1983 • 67 citations

Analysis in vivo of translational mutants of the rIIB cistron of bacteriophage T4

1981 • 64 citations

Primary structure of Escherichia coli ribosomal protein S1 and of its gene rpsA.

1982 • 62 citations

Effect of the sequences upstream from the ribosome-binding site on the yield of protein from the cloned gene for phage MS2 coat protein

1983 • 60 citations

Site-directed mutagenesis of ribosomal RNA

1982 • 58 citations

Site-specific mutagenesis using oligodeoxyribonucleotides: isolation of a phenotypically silent φX174 mutant, with a specific nucleotide deletion, at very high efficiency

1980 • 57 citations

Studies on the function of two adjacent N⁶, N⁶-dimethyladenosines near the 3′ end of 16 S ribosomal RNA of Escherichia coli. IV. The effect of the methylgroups on ribosomal subunit interaction

1980 • 57 citations

Site-directed mutagenesis of ribosomal RNA

1982 • 50 citations

Regions of DNA involved in the stringent control of plasmid-encoded rRNA in vivo

1983 • 48 citations

Functional Recognition of Phage RNA by 30-S Ribosomal Subunits in the Absence of Initiator tRNA

1980 • 28 citations