Basal DNA damage in individual human lymphocytes with age

A simple technique for quantitation of low levels of DNA damage in individual cells

1988 • 10,537 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Mixture models : inference and applications to clustering

1988 • 2,075 citations

Correlation Between Deoxyribonucleic Acid Excision-Repair and Life-Span in a Number of Mammalian Species

1974 • 738 citations

Handbook of the Biology of Aging

1986 • 572 citations

DNA damage and rpair with age in individual human lymphocytes

1990 • 214 citations

Theories of biological aging

1985 • 212 citations

Age-Associated Changes in the DNA of Mouse Tissue

1971 • 203 citations

DNA, mutations and aging

1989 • 158 citations

Genetic instability as the primary cause of human aging

1986 • 143 citations

DNA repair and replication in aging organisms and cells

1985 • 85 citations

Age-associated structural alterations in senescent mouse brain DNA

1977 • 67 citations

An assay for phosphotriester formation in the reaction of alkylating agents with deoxyribosenucleic acid in vitro and in vivo

1976 • 67 citations

The kinetics of the alkaline hydrolysis of phosphotriesters in DNA

1976 • 63 citations

Age-dependent decline in rejoining of X-ray-induced DNA double-strand breaks in normal human lymphocytes

1989 • 60 citations

Comparative studies of DNA size in various tissues of mice during the aging process

1976 • 54 citations

DNA Repair in Relation to the Aging Process

1987 • 39 citations

Age-dependent accumulation of alkali-labile sites in DNA of post-mitotic but not in that of mitotic rat liver cells

1988 • 36 citations

Spontaneous DNA breaks in the rat brain during development and aging

1990 • 35 citations

Age-correlated DNA damage in human muscle tissue

1987 • 30 citations

Absence of significant age-dependent increase of single-stranded DNA extracted from mouse liver nuclei

1978 • 29 citations

Age associated increase of single-stranded regions in the DNA of mouse brain and liver cells

1979 • 27 citations

Genome reorganization during cellular senescence

1984 • 25 citations

Age-related variations in human lymphocyte DNA

1981 • 23 citations

Changes in endogenous DNA damage in aging mice in response to butylated hydroxyanisole and oltipraz

1985 • 20 citations

Estimation of the single stranded region in the nuclear DNA of mouse tissues during aging with special reference to the brain

1982 • 20 citations

Susceptibility of mouse liver DNA to digestion by S1 nuclease: Absence of age-related change

1979 • 13 citations