AIDS dementia complex and HIV‐1 brain infection: Clinical‐virological correlations

The AIDS Dementia Complex

1988 • 1,387 citations

The AIDS dementia complex: II. Neuropathology

1986 • 1,280 citations

The Brain in AIDS: Central Nervous System HIV-1 Infection and AIDS Dementia Complex

1988 • 1,244 citations

Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients.

1986 • 1,242 citations

HTLV-III Infection in Brains of Children and Adults with AIDS Encephalopathy

1985 • 899 citations

Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus‐type 1 (HIV‐1) infection

1991 • 755 citations

Central nervous system damage produced by expression of the HIV-1 coat protein gpl20 in transgenic mice

1994 • 678 citations

Dementia in AIDS patients

1993 • 671 citations

Secretion of Neurotoxins by Mononuclear Phagocytes Infected with HIV-1

1990 • 628 citations

Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide

1988 • 616 citations

Cytokine expression in the brain during the acquired immunodeficiency syndrome

1992 • 572 citations

Quinolinic acid in cerebrospinal fluid and serum in HIV‐1 Infection: Relationship to clinical and neurological status

1991 • 563 citations

Pathogenesis of lentivirus infections

1986 • 558 citations

Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease.

1992 • 531 citations

Inhibition of Entry of HIV-1 in Neural Cell Lines by Antibodies Against Galactosyl Ceramide

1991 • 523 citations

Neocortical damage during HIV infection

1991 • 456 citations

Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells

1989 • 405 citations

HIV‐1 infection of subcortical astrocytes in the pediatric central nervous system

1994 • 402 citations

Immunohistochemical identification of HTLV‐III antigen in brains of patients with AIDS

1986 • 380 citations

Spectrum of human immunodeficiency virus–associated neocortical damage

1992 • 369 citations

Overexpression of nef as a marker for restricted HIV‐1 infection of astrocytes in postmortem pediatric central nervous tissues

1994 • 365 citations

Loss of neurons in the frontal cortex in AIDS brains

1990 • 355 citations

Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures.

1993 • 348 citations

Clinical‐neuropathologic correlation in HIV‐associated dementia

1993 • 325 citations

Brain pathology induced by infection with the human immunodeficiency virus (HIV)

1987 • 315 citations

Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains.

1991 • 289 citations

AIDS subacute encephalitis. Identification of HIV-infected cells.

1987 • 286 citations

In situ detection of polymerase chain reaction-amplified HIV-1 nucleic acids and tumor necrosis factor-alpha RNA in the central nervous system.

1994 • 283 citations

Biology and Pathogenesis of Lentiviruses

1989 • 281 citations

Zidovudine treatment of the AIDS dementia complex: Results of a placebo‐controlled trial

1993 • 275 citations

Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences

1994 • 259 citations

Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: an evaluation of cytokines in cerebrospinal fluid

1989 • 259 citations

Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-1 beta

1991 • 254 citations

Declining incidence of AIDS dementia complex after introduction of zidovudine treatment.

1989 • 235 citations

Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome

1994 • 230 citations

Morphology and distribution of HIV-1 gp41-positive microglia in subacute AIDS encephalitis

1990 • 212 citations

Cellular localization of an HIV-1 antigen in subacute AIDS encephalitis using an improved double-labeling immunohistochemical method.

1990 • 188 citations

Neopterin modulates toxicity mediated by reactive oxygen and chloride species

1993 • 175 citations

Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus.

1989 • 172 citations

Elevated alpha–tumor necrosis factor levels in spinal fluid from HIV‐1–infected patients with central nervous system involvement

1991 • 170 citations

Early Brain Changes in HIV Infection

1992 • 167 citations

Cerebrospinal fluid neopterin in human immunodeficiency virus type 1 infection

1990 • 161 citations

Human microglial cells: Characterization in cerebral tissue and in primary culture, and study of their susceptibility to HIV‐1 infection

1991 • 156 citations

Human Immunodeficiency Virus and the Brain: Investigation of Virus Load and Neuropathologic Changes in Pre-AIDS Subjects

1993 • 153 citations

Microglia in the giant cell encephalitis of acquired immune deficiency syndrome: proliferation, infection and fusion

1988 • 140 citations

Infection of human brain cells by HIV-1

1992 • 138 citations

Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and β2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients

1992 • 136 citations

Neopterin concentrations in cerebrospinal fluid and serum of individuals infected with HIV-1

1989 • 110 citations

Cerebrospinal fluid (β2-microglobulin in patients with AIDS dementia complex

1992 • 98 citations

Simian immunodeficiency virus?induced meningoencephalitis: Natural history and retrospective study

1988 • 97 citations

Elevated neopterin and beta2-microglobulin levels in blood and cerebrospinal fluid occur early in HIV-1 infection

1989 • 88 citations

Cerebrospinal fluid ß ₂ microglobulin in patients infected with human immunodeficiency virus

1989 • 80 citations

Susceptibility of human glial cells to infection with human immunodeficiency virus (HIV)

1987 • 75 citations

Dissociation of AIDS‐related vacuolar myelopathy and productive HIV‐1 infection of the spinal cord

1989 • 65 citations

Human choroid plexus cells can be latently infected with human immunodeficiency virus

1989 • 63 citations

Cellular localization of Nef expressed in persistently HIV-1 -infected low-producer astrocytes

1992 • 61 citations

Human immunodeficiency virus infection in microglia: Correlation between cells infected in the brain and cells cultured from infectious brain tissue

1992 • 59 citations

Expression of major histocompatibility complex and HIV antigens within the brains of AIDS patients

1991 • 58 citations

Human Immunodeficiency Virus Type 1 Antigen in Cerebrospinal Fluid

1989 • 52 citations

Understanding the AIDS dementia complex (ADC). The challenge of HIV and its effects on the central nervous system.

1994 • 42 citations

HIV replicates in cultured human brain cells.

1987 • 39 citations

Association between intrathecal anti-HIV-1 immunoglobulin G synthesis and occurrence of HIV-1 in cerebrospinal fluid

1989 • 32 citations

Cerebrospinal fluid HIV-1 p24 antigen and culture: sensitivity and specificity for AIDS-dementia complex.

1994 • 19 citations