Changes in the urinary excretion level of 8-hydroxyguanine by exposure to reactive oxygen-generating substances

The Biology of Oxygen Radicals

1978 • 3,361 citations

Dietary Carcinogens and Anticarcinogens

1983 • 3,028 citations

ON THE COLORIMETRIC DETERMINATION OF CREATININE BY THE JAFFE REACTION

1945 • 2,024 citations

Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

1988 • 1,709 citations

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.

1990 • 1,100 citations

Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair

1986 • 933 citations

Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage.

1989 • 733 citations

Endogenous Oxidative DNA Damage, Aging, and Cancer

1989 • 711 citations

8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity.

1991 • 678 citations

Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity

1974 • 540 citations

Protein oxidation and proteolysis during aging and oxidative stress

1989 • 396 citations

Biological effects of diesel exhaust particles. I. in vitro production of superoxide and in vivo toxicity in mouse

1993 • 362 citations

Spontaneous cancer and its possible relationship to oxygen metabolism.

1980 • 298 citations

Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column.

1992 • 292 citations

Endogenous oxidative damage of deoxycytidine in DNA.

1992 • 280 citations

Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane.

1989 • 250 citations

Oxygen toxicity and reactive oxygen metabolites in mammals

1989 • 228 citations

Oxygen radicals in lung pathology

1990 • 227 citations

Oxygen radicals, inflammation, and arthritis: Pathophysiological considerations and implications for treatment

1991 • 174 citations

Cigarette smoke-induced DNA damage in cultured human lung cells: Role of hydroxyl radicals and endonuclease activation

1992 • 158 citations

An endonuclease activity of Escherichia coli that specifically removes 8-hydroxyguanine residues from DNA

1991 • 149 citations

A proposed mechanism of benzene toxicity: Formation of reactive intermediates from polyphenol metabolites

1981 • 136 citations

Cigarette smoke-induced DNA-damage: Role of hydroquinone and catechol in the formation of the oxidative DNA-adduct, 8-hydroxydeoxyguanosine

1990 • 126 citations

Generation of hydrogen peroxide and superoxide anion radical from cigarette smoke.

1984 • 123 citations

An endonuclease activity in human polymorphonuclear neutrophils that removes 8-hydroxyguanine residues from DNA

1991 • 84 citations

Comparison of oxidative damage to rat liver DNA and RNA by primary nitroalkanes, secondary nitroalkanes, cyclopentanone oxime, and related compounds.

1991 • 67 citations

Diesel soot particles catalyze the production of oxy-radicals

1989 • 55 citations