Thymocyte-targeted overexpression of xiap transgene disrupts T lymphoid apoptosis and maturation

Apoptosis by Death Factor

1997 • 5,038 citations

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1992 • 2,932 citations

Caspases: Intracellular Signaling by Proteolysis

1997 • 2,114 citations

X-linked IAP is a direct inhibitor of cell-death proteases

1997 • 1,961 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1996 • 1,902 citations

Cell Death in Development

1999 • 1,567 citations

Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand

1994 • 1,549 citations

Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity

1999 • 1,500 citations

Differential Requirement for Caspase 9 in Apoptotic Pathways In Vivo

1998 • 1,292 citations

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1991 • 1,223 citations

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1991 • 1,090 citations

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1996 • 1,027 citations

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1998 • 985 citations

Fas and Fas ligand: lpr and gld mutations

1995 • 906 citations

Negative selection of lymphocytes

1994 • 810 citations

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis.

1995 • 791 citations

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1990 • 629 citations

Positive selection of lymphocytes

1994 • 563 citations

Bcl-2 Can Rescue T Lymphocyte Development in Interleukin-7 Receptor–Deficient Mice but Not in Mutant rag-1 −/− Mice

1997 • 503 citations

Early Activation of Caspases during T Lymphocyte Stimulation Results in Selective Substrate Cleavage in Nonapoptotic Cells

1999 • 387 citations

Interleukin-15 protects from lethal apoptosis in vivo

1997 • 339 citations

Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase.

1990 • 235 citations

Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice.

1995 • 178 citations

Bcl-2 expression promotes B- but not T-lymphoid development in scid mice

1994 • 157 citations

Thymus-derived Glucocorticoids Regulate Antigen-specific Positive Selection

1997 • 139 citations

Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events

1999 • 120 citations

In vitro stimulation of mouse thymus cells by PHA and allogeneic cells

1971 • 112 citations

XIAP Regulates DNA Damage-induced Apoptosis Downstream of Caspase-9 Cleavage

2000 • 96 citations

Cell Division Regulation by BIR1, a Member of the Inhibitor of Apoptosis Family in Yeast

2000 • 83 citations

The T cell receptor repertoire of CD4-8+ thymocytes is altered by overexpression of the BCL-2 protooncogene in the thymus.

1994 • 76 citations

Changes in the relative abundance of type I and type II lck mRNA transcripts suggest differential promoter usage during T-cell development.

1990 • 62 citations

Thymocyte apoptosis.

1999 • 21 citations

Changes in the Relative Abundance of Type I and Type II lck mRNA Transcripts Suggest Differential Promoter Usage during T-Cell Development

1990 • 16 citations