DNA Strand Break Formation Following Exposure of Bovine Pulmonary Artery and Aortic Endothelial Cells to Reactive Oxygen Products

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel Filtration

1968 • 2,659 citations

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite.

1989 • 1,273 citations

An enzyme-release assay for natural cytotoxicity

1983 • 1,063 citations

Enthalpy of decomposition of hydrogen peroxide by catalase at 25° C (with molar extinction coefficients of H2O2 solutions in the UV)

1972 • 895 citations

Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide.

1988 • 614 citations

Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide.

1986 • 520 citations

Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase.

1986 • 466 citations

Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation.

1981 • 448 citations

Phagocytes as Carcinogens: Malignant Transformation Produced by Human Neutrophils

1985 • 443 citations

Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion.

1988 • 421 citations

Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes.

1985 • 397 citations

Oxidant-induced DNA damage of target cells.

1988 • 382 citations

Pathogenesis of the adult respiratory distress syndrome. Evidence of oxidant activity in bronchoalveolar lavage fluid.

1983 • 340 citations

OXIDANT ACTIVITY IN EXPIRED BREATH OF PATIENTS WITH ADULT RESPIRATORY DISTRESS SYNDROME

1986 • 330 citations

A quantitative fluorimetric assay for the determination of oxidant production by polymorphonuclear leukocytes: Its use in the simultaneous fluorimetric assay of cellular activation processes

1984 • 322 citations

Alterations in adenosine triphosphate and energy charge in cultured endothelial and P388D1 cells after oxidant injury.

1985 • 268 citations

High glucose induces DNA damage in cultured human endothelial cells.

1986 • 244 citations

Hydrogen peroxide or heat shock induces resistance to hydrogen peroxide in Chinese hamster fibroblasts

1987 • 217 citations

Comparison of the effects of hydrogen peroxide and X-ray irradiation on toxicity, mutation, and DNA damage/repair in mammalian cells (V-79)

1981 • 163 citations

Glutathione cycle activity and pyridine nucleotide levels in oxidant-induced injury of cells.

1985 • 162 citations

Isolation, culture, and subculture of bovine pulmonary artery endothelial cells: Mechanical methods

1986 • 114 citations

Tumor promoter phorbol 12-myristate 13-acetate induces a clastogenic factor in human lymphocytes.

1982 • 108 citations

Mechanisms of Endothelial Cell ATP Depletion after Oxidant Injury

1989 • 66 citations

Tumor promoter phorbol-12-myristate-13-acetate induces poly ADP-ribosylation in human monocytes

1985 • 41 citations

Immunofluorescence and immunocytochemistry of endothelial surface antigens

1986 • 23 citations