Polyphosphoinositides Inhibit the Interaction of Vinculin with Actin Filaments

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The Regulation of Rabbit Skeletal Muscle Contraction

1971 • 4,491 citations

[10] Assay of inorganic phosphate, total phosphate and phosphatases

1966 • 3,302 citations

Phosphoinositides and Calcium as Regulators of Cellular Actin Assembly and Disassembly

1994 • 524 citations

Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

1996 • 522 citations

Vinculin knockout results in heart and brain defects during embryonic development

1998 • 511 citations

Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes.

1980 • 502 citations

Identification of a factor in conventional muscle actin preparations which inhibits actin filament self-association

1980 • 473 citations

A rapid purification of alpha-actinin, filamin, and a 130,000-dalton protein from smooth muscle.

1980 • 395 citations

F-actin binding site masked by the intramolecular association of vinculin head and tail domains

1995 • 371 citations

Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown.

1993 • 335 citations

The Crystal Structure of Plasma Gelsolin: Implications for Actin Severing, Capping, and Nucleation

1997 • 294 citations

Suppression of tumorigenicity in transformed cells after transfection with vinculin cDNA.

1992 • 228 citations

An intramolecular association between the head and tail domains of vinculin modulates talin binding.

1994 • 212 citations

Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion.

1995 • 203 citations

Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells

1993 • 199 citations

Vinculin is essential for muscle function in the nematode.

1991 • 173 citations

The interaction of the cell-contact proteins VASP and vinculin is regulated by phosphatidylinositol-4,5-bisphosphate

1998 • 155 citations

Acidic phospholipids inhibit the intramolecular association between the N- and C-terminal regions of vinculin, exposing actin-binding and protein kinase C phosphorylation sites

1996 • 150 citations

Overexpression of vinculin suppresses cell motility in BALB/c 3T3 cells

1992 • 149 citations

Tertiary Structure of Destrin and Structural Similarity between Two Actin-Regulating Protein Families

1996 • 137 citations

Rescue of the mutant phenotype by reexpression of full-length vinculin in null F9 cells; effects on cell locomotion by domain deleted vinculin

1998 • 131 citations

Focal adhesion formation by f9 embryonal carcinoma cells after vinculin gene disruption

1995 • 110 citations

Characterization of Two F‐Actin‐Binding and Oligornerization Sites in the Cell‐Contact Protein Vinculin

1997 • 99 citations

A Conserved Motif in the Tail Domain of Vinculin Mediates Association with and Insertion into Acidic Phospholipid Bilayers

1998 • 91 citations

Structure of Actin Binding Proteins: Insights about Function at Atomic Resolution

1994 • 90 citations

Measurement of rate constants for actin filament elongation in solution

1983 • 88 citations

The structure of divalent cation-induced aggregates of PIP2 and their alteration by gelsolin and tau

1997 • 86 citations

cDNA-derived sequence of chicken embryo vinculin.

1988 • 83 citations

The Ultrastructure of Chicken Gizzard Vinculin as Visualized by High-Resolution Electron Microscopy

1996 • 76 citations

The Carboxy-Terminal Tail Domain of Vinculin Contains a Cryptic Binding Site for Acidic Phospholipids

1995 • 74 citations

Interaction of the 47-kDa talin fragment and the 32-kDa vinculin fragment with acidic phospholipids: a computer analysis

1995 • 57 citations

Vinculin, talin and focal adhesions

1996 • 42 citations

Metabolic radiolabeling techniques for identification of prenylated and fatty acylated proteins

1990 • 36 citations

Intramolecular interactions regulate serine/threonine phosphorylation of vinculin

1996 • 32 citations

Purification and characterization of an 85 kDa talin‐binding fragment of vinculin

1990 • 28 citations

Isolation of peptides from phage-displayed random peptide libraries that interact with the talin-binding domain of vinculin

1997 • 19 citations