Inhibition of respiratory viruses by nasally administered siRNA

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

Asymmetry in the Assembly of the RNAi Enzyme Complex

2003 • 2,761 citations

Functional siRNAs and miRNAs Exhibit Strand Bias

2003 • 2,516 citations

Expression profiling reveals off-target gene regulation by RNAi

2003 • 2,294 citations

Rational siRNA design for RNA interference

2004 • 1,991 citations

MicroRNAs in plants

2002 • 1,791 citations

Activation of the interferon system by short-interfering RNAs

2003 • 1,416 citations

Respiratory Syncytial Virus

1976 • 1,125 citations

RNA interference targeting Fas protects mice from fulminant hepatitis

2003 • 1,106 citations

Induction of an interferon response by RNAi vectors in mammalian cells

2003 • 972 citations

The RNAi revolution

2004 • 721 citations

Inhibition of hepatitis B virus in mice by RNA interference

2003 • 616 citations

Sequence-Specific Inhibition of Small RNA Function

2004 • 577 citations

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)

2003 • 530 citations

Inhibition of influenza virus production in virus-infected mice by RNA interference

2004 • 441 citations

Human Immunodeficiency Virus Type 1 Escapes from RNA Interference-Mediated Inhibition

2004 • 432 citations

Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

2004 • 385 citations

A Role for Immune Complexes in Enhanced Respiratory Syncytial Virus Disease

2002 • 383 citations

Primary respiratory syncytial virus infection in mice

1988 • 381 citations

Protection against lethal influenza virus challenge by RNA interferencein vivo

2004 • 369 citations

Simultaneous detection of fourteen respiratory viruses in clinical specimens by two multiplex reverse transcription nested‐PCR assays

2004 • 290 citations

Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses.

2001 • 285 citations

Respiratory Syncytial Virus Genetic and Antigenic Diversity

2000 • 276 citations

Bovine Respiratory Syncytial Virus Nonstructural Proteins NS1 and NS2 Cooperatively Antagonize Alpha/Beta Interferon-Induced Antiviral Response

2000 • 244 citations

Animal Pneumoviruses: Molecular Genetics and Pathogenesis

2004 • 198 citations

Respiratory Syncytial Virus Genetic and Antigenic Diversity

2000 • 197 citations

The Release of Leukotrienes in the Respiratory Tract during Infection with Respiratory Syncytial Virus: Role in Obstructive Airway Disease

1988 • 192 citations

Inducible Expression of Inflammatory Chemokines in Respiratory Syncytial Virus-Infected Mice: Role of MIP-1α in Lung Pathology

2001 • 180 citations

The Role of IFN in Respiratory Syncytial Virus Pathogenesis

2002 • 176 citations

Respiratory syncytial virus. I. Concentration and purification of the infectious virus.

1978 • 138 citations

Phosphatidylcholine Molecular Species in Lung Surfactant

2001 • 128 citations

Role of Cellular Actin in the Gene Expression and Morphogenesis of Human Respiratory Syncytial Virus

1998 • 123 citations

Specific Inhibition of Type I Interferon Signal Transduction by Respiratory Syncytial Virus

2004 • 117 citations

Enhanced Disease and Pulmonary Eosinophilia Associated with Formalin-Inactivated Respiratory Syncytial Virus Vaccination Are Linked to G Glycoprotein CX3C-CX3CR1 Interaction and Expression of Substance P

2003 • 113 citations

Recombinant Bovine/Human Parainfluenza Virus Type 3 (B/HPIV3) Expressing the Respiratory Syncytial Virus (RSV) G and F Proteins Can Be Used To Achieve Simultaneous Mucosal Immunization against RSV and HPIV3

2001 • 102 citations

New drugs and treatment for respiratory syncytial virus

2004 • 91 citations

Respiratory Syncytial Virus Affects Pulmonary Function in BALB/c Mice

1998 • 89 citations

Control of nonsegmented negative-strand RNA virus replication by siRNA

2004 • 85 citations

Profilin Is Required for Optimal Actin-Dependent Transcription of Respiratory Syncytial Virus Genome RNA

2000 • 80 citations

Structural characterization of respiratory syncytial virus fusion inhibitor escape mutants: homology model of the F protein and a syncytium formation assay

2003 • 73 citations

Involvement of Actin Microfilaments in the Replication of Human Parainfluenza Virus Type 3

1998 • 65 citations

Potential therapeutic implications of new insights into respiratory syncytial virus disease

2002 • 47 citations

RSV entry inhibitors block F-protein mediated fusion with model membranes

2002 • 36 citations

African green monkeys provide a useful nonhuman primate model for the study of human parainfluenza virus types-1, -2, and -3 infection

2000 • 34 citations

The Complex Relationship between Respiratory Syncytial Virus and Allergy in Lung Disease

2003 • 26 citations

Zileuton Reduces Respiratory Illness and Lung Inflammation, during Respiratory Syncytial Virus Infection, in Mice

2003 • 26 citations

Bovine parainfluenza virus type 3 (PIV3) expressing the respiratory syncytial virus (RSV) attachment and fusion proteins protects hamsters from challenge with human PIV3 and RSV

2003 • 22 citations