Functional differences between memory and naive CD8 T cells

A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1995 • 5,208 citations

Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection

1998 • 1,996 citations

Immunological Memory and Protective Immunity: Understanding Their Relation

1996 • 1,771 citations

Clonal selection and learning in the antibody system

1996 • 1,710 citations

Potent and Selective Stimulation of Memory-Phenotype CD8+ T Cells In Vivo by IL-15

1998 • 1,262 citations

T Cell Activation Determined by T Cell Receptor Number and Tunable Thresholds

1996 • 1,038 citations

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

Turnover of naive- and memory-phenotype T cells.

1994 • 900 citations

Differential Requirements for Survival and Proliferation of CD8 Naïve or Memory T Cells

1997 • 875 citations

Cytotoxic T-cell memory without antigen

1994 • 669 citations

Rapid Effector Function in CD8+ Memory T Cells

1997 • 652 citations

Variability in the Lambda Light Chain Sequences of Mouse Antibody

1970 • 554 citations

Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

1984 • 534 citations

Virus-specific CD8+ T-cell memory determined by clonal burst size

1994 • 525 citations

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

1988 • 505 citations

ON IMMUNOLOGICAL MEMORY

1996 • 482 citations

Antigen-Specific Development of Primary and Memory T Cells in Vivo

1995 • 444 citations

Lymphocyte life-span and memory

1994 • 405 citations

Generation and in vivo persistence of polarized Th1 and Th2 memory cells

1994 • 283 citations

Stable Expression and Somatic Hypermutation of Antibody V Regions in B-Cell Developmental Pathways

1989 • 271 citations

Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts.

1996 • 259 citations

T cell clonal anergy

1997 • 257 citations

Resting Memory CD8+ T Cells are Hyperreactive to Antigenic Challenge In Vitro

1996 • 241 citations

Self-MHC-restricted peptides recognized by an alloreactive T lymphocyte clone.

1996 • 205 citations

High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins.

1994 • 200 citations

Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules

1998 • 186 citations

Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera.

1984 • 183 citations

On the cellular basis of immunological T cell memory

1995 • 159 citations

Modifications of CD8+ T Cell Function during In Vivo Memory or Tolerance Induction

1998 • 134 citations

Immunological memory

1997 • 124 citations

Qualitative Differences Between Naive and Memory T Cells Make a Major Contribution to the More Rapid and Efficient Memory CD8+ T Cell Response

1998 • 103 citations

Perforin, a pore-forming protein detectable by monoclonal antibodies, is a functional marker for killer cells

1990 • 93 citations

THE RELATIVE AFFINITY OF ANTIBODIES SYNTHESIZED IN THE SECONDARY RESPONSE

1967 • 83 citations

Distinct phenotypes of antigen-selected CD8 T cells emerge at different stages of an in vivo immune response.

1995 • 67 citations

The immune response to a simple antigenic determinant.

1966 • 43 citations

Inactivation and proteolytic degradation of perforin within lytic granules upon neutralization of acidic pH

1997 • 37 citations