Rapid Dissociation of Human Apurinic Endonuclease (Ape1) from Incised DNA Induced by Magnesium

Instability and decay of the primary structure of DNA

1993 • 5,370 citations

The Chemical Basis of Radiation Biology

1987 • 1,843 citations

REPAIR OF OXIDATIVE DAMAGE TO DNA: Enzymology and Biology

1994 • 1,435 citations

MUTAGENESIS BY APURINIC/APYRIMIDINIC SITES

1986 • 884 citations

The base excision repair pathway

1995 • 536 citations

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes.

1991 • 526 citations

Structure and function of the multifunctional DNA-repair enzyme exonuclease III

1995 • 382 citations

A Deoxyribonucleic Acid Phosphatase-Exonuclease from Escherichia coli

1964 • 332 citations

DNA Polymerase β Conducts the Gap-filling Step in Uracil-initiated Base Excision Repair in a Bovine Testis Nuclear Extract

1995 • 317 citations

The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites

1997 • 316 citations

Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants

1991 • 294 citations

Incision Activity of Human Apurinic Endonuclease (Ape) at Abasic Site Analogs in DNA

1995 • 275 citations

Two distinct human DNA diesterases that hydrolyze 3′-blocking deoxyribose fragments from oxidized DNA

1991 • 265 citations

Endonuclease II of Escherichia coli is exonuclease III.

1976 • 198 citations

3'-Phosphodiesterase activity of human apurinic/apyrimidinic endonuclease at DNA double-strand break ends

1997 • 172 citations

Purification and characterization of an apurinic/apyrimidinic endonuclease from HeLa cells.

1981 • 161 citations

Substrate Binding by Human Apurinic/Apyrimidinic Endonuclease Indicates a Briggs-Haldane Mechanism

1997 • 154 citations

Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1

1995 • 130 citations

Mutations simultaneously affecting endonuclease II and exonuclease III in Escherichia coli.

1975 • 128 citations

cDNA cloning, sequencing, expression and possible domain structure of human APEX nuclease homologous to Escherichia coli exonuclease III

1992 • 122 citations

Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity

1995 • 119 citations

Dynamics of the Interaction of Human Apurinic Endonuclease (Ape1) with Its Substrate and Product

1998 • 112 citations

Removal of 3′-phosphoglycolate from DNA strand-break damage in an oligonucleotide substrate by recombinant human apurinic/apyrimidinic endonuclease 1

1994 • 95 citations

Abasic Site Binding by the Human Apurinic Endonuclease, Ape, and Determination of the DNA Contact Sites

1997 • 92 citations

Yeast DNA 3′-repair diesterase is the major cellular apurinic/apyrimidinic endonuclease: substrate specificity and kinetics.

1988 • 91 citations

Analysis of class II (hydrolytic) and class I (β-lyase) apurinic/apyrimidinic endonucleases with a synthetic DNA substrate

1990 • 87 citations

Drosophila Rrp1 protein: an apurinic endonuclease with homologous recombination activities.

1991 • 62 citations

Mechanism of action of Escherichia coli exonuclease III

1989 • 52 citations

Asparagine 212 is essential for abasic site recognition by the human DNA repair endonuclease HAP1

1996 • 44 citations