A Human Keratinocyte Cell Line Produces Two Autocrine Growth Inhibitors, Transforming Growth Factor-β and Insulin-like Growth Factor Binding Protein-6, in a Calcium- and Cell Density-dependent Manner

Seria cultivation of strains of human epidemal keratinocytes: the formation keratinizin colonies from single cell is

1975 • 4,443 citations

Silver stain for proteins in polyacrylamide gels: A modified procedure with enhanced uniform sensitivity

1981 • 4,191 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

1980 • 1,810 citations

Peptide Growth Factors and Their Receptors

1991 • 1,221 citations

Human KGF is FGF-Related with Properties of a Paracrine Effector of Epithelial Cell Growth

1989 • 989 citations

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture.

1989 • 914 citations

Purification and characterization of a newly identified growth factor specific for epithelial cells.

1989 • 842 citations

An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes.

1989 • 767 citations

Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6)

1991 • 680 citations

Cellular Localization of Somatomedin (Insulin-Like Growth Factor) Messenger RNA in the Human Fetus

1987 • 663 citations

Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium.

1986 • 559 citations

Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor.

1991 • 521 citations

Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition

1993 • 481 citations

Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development.

1989 • 440 citations

Integrated control of growth and differentiation of normal human prokeratinocytes cultured in serum‐free medium: Clonal analyses, growth kinetics, and cell cycle studies

1984 • 414 citations

Expression of Somatomedin/Insulin-Like Growth Factor Messenger Ribonucleic Acids in the Human Fetus: Identification, Characterization, and Tissue Distribution*

1988 • 375 citations

Purification and properties of a type .beta. transforming growth factor from bovine kidney

1983 • 355 citations

Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis.

1989 • 333 citations

Purification and properties of an endothelial cell growth factor from human platelets.

1987 • 330 citations

Isolation and Molecular Cloning of Insulin-Like Growth Factor-Binding Protein-6

1991 • 233 citations

Marked stimulation of growth and motility of human keratinocytes by hepatocyte growth factor

1991 • 217 citations

Transforming Growth Factor-β: Latent Forms, Binding Proteins and Receptors

1993 • 215 citations

Human transforming growth factor type .beta.2: production by a prostatic adenocarcinoma cell line, purification, and initial characterization

1987 • 204 citations

Identification of a polypeptide growth inhibitor from bovine mammary gland. Sequence homology to fatty acid- and retinoid-binding proteins.

1987 • 201 citations

Requirement for receptor‐bound urokinase in plasmin‐dependent cellular conversion of latent TGF‐β to TGF‐β

1994 • 176 citations

Purification of kidney epithelial cell growth inhibitors.

1980 • 174 citations

Identification of Somatomedin/Insulin-Like Growth Factor Immunoreactive Cells in the Human Fetus

1987 • 165 citations

Tissue-Specific and Developmentally Regulated Transcription of the Insulin-Like Growth Factor 2 Gene

1987 • 161 citations

Growth and differentiation of human keratinocytes without a feeder layer or conditioned medium

1980 • 159 citations

In vitro paracrine regulation of human keratinocyte growth by fibroblast‐derived insulin‐like growth factors

1992 • 156 citations

Amino acid sequence of the BSC-1 cell growth inhibitor (polyergin) deduced from the nucleotide sequence of the cDNA.

1988 • 134 citations

TGF-beta and retinoic acid: regulators of growth and modifiers of differentiation in human epidermal cells.

1990 • 129 citations

Interactions of recombinant and platelet transforming growth factor-β1 precursor with the insulin-like growth factor II/mannose 6-phosphate receptor

1989 • 127 citations

Insulin-Like Growth Factor Binding Proteins: Structural and Molecular Relationships

1991 • 120 citations

Isolation from human cerebrospinal fluid of a new insulin‐like growth factor‐binding protein with a selective affinity for IGF‐II

1989 • 116 citations

Isolation from adult human serum of four insulin-like growth factor (IGF) binding proteins and molecular cloning of one of them that is increased by IGF I administration and in extrapancreatic tumor hypoglycemia.

1990 • 114 citations

Identification and molecular cloning of two new 30-kDa insulin-like growth factor binding proteins isolated from adult human serum

1991 • 109 citations

Fine structure of subcultivated stratified squamous epithelium grown on collagen rafts

1980 • 104 citations

Purification and properties of a novel insulin-like growth factor-II binding protein from transformed human fibroblasts.

1990 • 103 citations

The molecular and cellular biology of insulin-like growth factor II

1992 • 100 citations

Induction and Autocrine Receptor Binding of Transforming Growth Factor-β2 during Terminal Differentiation of Primary Mouse Keratinocytes

1990 • 81 citations

Regulation of immunoreactive insulin-like growth factor binding protein-6 in normal and transformed human fibroblasts

1994 • 41 citations

Further Characterization of the Keratinocyte Somatomedin-C/Insulin-like Growth Factor I (SM-C/IGF-I) Receptor and the Biological Responsiveness of Cultured Keratinocytes to SM-C/IGF-I

1988 • 23 citations

Differential localization of TGF-β-precursor isotypes in normal human skin

1994 • 14 citations