Human Phagocytes Employ the Myeloperoxidase-Hydrogen Peroxide System to Synthesize Dityrosine, Trityrosine, Pulcherosine, and Isodityrosine by a Tyrosyl Radical-dependent Pathway

MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy

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Role of oxidized low density lipoprotein in atherogenesis.

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Oxygen-Dependent Microbial Killing by Phagocytes

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Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

1989 • 1,914 citations

The role of oxidized lipoproteins in atherogenesis

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Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.

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Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells.

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Comparison of different modes of two-dimensional reverse-correlation NMR for the study of proteins

1990 • 510 citations

Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.

1993 • 486 citations

Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits.

1990 • 478 citations

Biological reactivity of hypochlorous acid: implications for microbicidal mechanisms of leukocyte myeloperoxidase.

1981 • 443 citations

Brominating Oxidants Generated by Human Eosinophils

1986 • 364 citations

The Oxidation of Tyramine, Tyrosine, and Related Compounds by Peroxidase

1959 • 363 citations

Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins.

1993 • 345 citations

Tyrosyl radical generated by myeloperoxidase is a physiological catalyst for the initiation of lipid peroxidation in low density lipoprotein.

1994 • 334 citations

Release of ovoperoxidase from sea urchin eggs hardens the fertilization membrane with tyrosine crosslinks

1977 • 313 citations

Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages

1993 • 311 citations

Isodityrosine, a new cross-linking amino acid from plant cell-wall glycoprotein

1982 • 311 citations

Lipid peroxidation and its role in atherosclerosis

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A Method for Determination of Low Carbon Monoxide Concentration in Blood

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Chlorohydrin formation from unsaturated fatty acids reacted with hypochlorous acid

1992 • 255 citations

Kinetics of Oxidation of Tyrosine and Dityrosine by Myeloperoxidase Compounds I and II

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Leukocytic Oxygen Activation and Microbicidal Oxidative Toxin

1989 • 225 citations

Isolation of two developmentally regulated genes involved in spore wall maturation in Saccharomyces cerevisiae.

1990 • 190 citations

Dityrosine: In vitro production and characterization

1984 • 173 citations

Dityrosine is a prominent component of the yeast ascospore wall. A proof of its structure.

1986 • 159 citations

The effect of oxygen, antioxidants, and superoxide radical on tyrosine phenoxyl radical dimerization

1989 • 148 citations

Scavenger receptor-independent stimulation of cholesterol esterification in macrophages by low density lipoprotein extracted from human aortic intima.

1992 • 147 citations

Cholesterol Chlorohydrin Synthesis by the Myeloperoxidase-Hydrogen Peroxide-Chloride System: Potential Markers for Lipoproteins Oxidatively Damaged by Phagocytes

1994 • 142 citations

Oxidative damage to fibronectin

1991 • 139 citations

Isolation of low density lipoprotein from atherosclerotic vascular tissue of Watanabe heritable hyperlipidemic rabbits.

1988 • 135 citations

Oxidation of low density lipoprotein leads to particle aggregation and altered macrophage recognition.

1992 • 134 citations

Myeloperoxidase-catalyzed incorporation of amines into proteins: role of hypochlorous acid and dichloramines

1982 • 132 citations

Oxidative tyrosylation of high density lipoprotein by peroxidase enhances cholesterol removal from cultured fibroblasts and macrophage foam cells.

1993 • 128 citations

Oxidative coupling of phenolic compounds

1965 • 124 citations

Purification and properties of ovoperoxidase, the enzyme responsible for hardening the fertilization membrane of the sea urchin egg.

1984 • 115 citations

Phenol Coupling Initiated by One-electron Oxidation of Tyrosine Units in Peptides and Histone

1983 • 112 citations

Properties of the Bacillus subtilis spore coat

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Phenol Oxidation Reactions

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p-Hydroxyphenylacetaldehyde Is the Major Product of L-Tyrosine Oxidation by Activated Human Phagocytes

1996 • 103 citations

Occurrence of dityrosine in Tussah silk fibroin and keratin

1971 • 97 citations

Differential inactivation of Escherichia coli membrane dehydrogenases by a myeloperoxidase-mediated antimicrobial system

1990 • 89 citations

Crystallization and Properties of Myeloperoxidase from Normal Human Leukocytes

1986 • 61 citations

A pulse radiolysis investigation of the reactions of myeloperoxidase with superoxide and hydrogen peroxide

1988 • 58 citations

Isolation and characterization of the receptor on human neutrophils that mediates cellular adherence.

1987 • 53 citations

Lipoprotein oxidation and gene expression in the artery wall

1993 • 51 citations

Pulcherosine, a novel tyrosine-derived, trivalent crosslinking amino acid from the fertilization envelope of sea urchin embryo

1990 • 47 citations