Both insulin and epidermal growth factor stimulate fatty acid synthesis and increase phosphorylation of acetyl‐CoA carboxylase and ATP‐citrate lyase in isolated hepatocytes

Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine.

1982 • 441 citations

The effect of serum, EGF, PGF2α and insulin on S6 phosphorylation and the initiation of protein and DNA synthesis

1982 • 362 citations

Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats

1976 • 357 citations

Platelet-derived growth factor stimulates tyrosine-specific protein kinase activity in Swiss mouse 3T3 cell membranes.

1982 • 293 citations

Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I

1983 • 254 citations

Studies on Rat Adipose Tissue in Vitro

1960 • 244 citations

Affinity labeling of the protein kinase associated with the epidermal growth factor receptor in membrane vesicles from A431 cells.

1982 • 232 citations

Separation and Characterisation of Glycogen Synthase Kinase 3,Glycogen Synthase Kinase 4 and Glycogen Synthase Kinase 5 from Rabbit Skeletal Muscle

1982 • 175 citations

Evidence that insulin activates fat-cell acetyl-CoA carboxylase by increased phosphorylation at a specific site

1982 • 117 citations

Reversible Phosphorylation and Inactivation of Acetyl‐CoA Carboxylase from Lactating Rat Mammary Gland by Cyclic AMP‐Dependent Protein Kinase

1980 • 111 citations

Purification of a hepatic 123,000-dalton hormone-stimulated 32P-peptide and its identification as ATP-citrate lyase.

1979 • 109 citations

Description of a protein kinase derived from insulin-treated 3T3-L1 cells that catalyzes the phosphorylation of ribosomal protein S6 and casein.

1983 • 106 citations

Short‐term effects of insulin and glucagon on lipid synthesis in isolated rat hepatocytes

1978 • 106 citations

Glucagon regulation of protein phosphorylation. Identification of acetyl coenzyme A carboxylase as a substrate.

1979 • 104 citations

Effect of glucagon on hepatic malonyl coenzyme A concentration and on lipid synthesis.

1977 • 99 citations

Adrenaline and the regulation of acetyl-coenzyme A carboxylase in rat epididymal adipose tissue. Inactivation of the enzyme is associated with phosphorylation and can be reversed on dephosphorylation

1979 • 97 citations

Glucagon inhibits fatty acid synthesis in isolated hepatocytes via phosphorylation of acetyl-CoA carboxylase by cyclic-AMP-dependent protein kinase

1984 • 95 citations

Stimulation of site-specific phosphorylation of acetyl coenzyme A carboxylase by insulin and epinephrine.

1983 • 87 citations

Effects of glucagon and insulin on cytoplasmic protein phosphorylation in hepatocytes

1978 • 82 citations

ATP-citrate lyase. Structure of a tryptic peptide containing the phosphorylation site directed by glucagon and the cAMP-dependent protein kinase.

1981 • 79 citations

Purification and Physicochemical Properties of ATP Citrate (pro‐3S) Lyase from Lactating Rat Mammary Gland and Studies of Its Reversible Phosphorylation

1981 • 73 citations

Characteristics of Insulin and Epidermal Growth Factor Stimulation of Receptor Autophosphorylation in Detergent Extracts of Rat Liver and Transplantable Rat Hepatomas*

1984 • 72 citations

Insulin and growth factors stimulate the phosphorylation of a Mr-22000 protein in 3T3-L1 adipocytes

1983 • 67 citations

The insulin-directed phosphorylation site on ATP-citrate lyase is identical with the site phosphorylated by the cAMP-dependent protein kinase in vitro.

1982 • 61 citations

Studies on insulin-stimulated phosphorylation of acetyl-CoA carboxylase, ATP citrate lyase and other proteins in rat epididymal adipose tissue. Evidence for activation of a cyclic AMP-independent protein kinase

1984 • 55 citations

Stimulation by epinephrine of in vivo phosphorylation and inactivation of acetyl coenzyme A carboxylase of rat epididymal adipose tissue.

1979 • 54 citations

Regulation of acetyl‐CoA carboxylase: identity of sites phosphorylated in intact cells treated with adrenaline and in vitro by cyclic AMP‐dependent protein kinase

1980 • 50 citations

Isolation of three cyclic-AMP-independent acetyl-CoA carboxylase kinases from lactating rat mammary gland and characterization of their effects on enzyme activity

1984 • 43 citations

Phosphorylation of acetyl-coenzyme A carboxylase by casein kinase I and casein kinase II

1983 • 38 citations

Inhibition of acetyl-CoA carboxylase activity in isolated rat adipocytes incubated with glucagon. Interactions with the effects of insulin, adrenaline and adenosine deaminase

1982 • 20 citations