Phosphorylation of αB-Crystallin in Response to Various Types of Stress

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1994 • 3,285 citations

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

1995 • 2,723 citations

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1994 • 1,684 citations

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of hsp27

1994 • 866 citations

Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin.

1982 • 792 citations

LENS CRYSTALLINS: THE EVOLUTION AND EXPRESSION OF PROTEINS FOR A HIGHLY SPECIALIZED TISSUE

1988 • 770 citations

αB-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

1989 • 546 citations

αB subunit of lens-specific protein α-crystallin is present in other ocular and non-ocular tissues

1989 • 538 citations

Alpha B-crystallin is a small heat shock protein.

1991 • 526 citations

Phosphorylation and supramolecular organization of murine small heat shock protein HSP25 abolish its actin polymerization-inhibiting activity.

1994 • 493 citations

MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase.

1992 • 486 citations

Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II.

1992 • 464 citations

Chaperone activity of alpha-crystallins modulates intermediate filament assembly.

1994 • 415 citations

Expression of the murine alpha B-crystallin gene is not restricted to the lens.

1989 • 377 citations

The Amino‐Acid Sequence of the αA₂ Chain of Bovine α‐Crystallin

1973 • 304 citations

Sequence and organization of genes encoding the human 27 kDa heat shock protein

1986 • 299 citations

Cellular distribution of alpha B-crystallin in non-lenticular tissues.

1990 • 295 citations

Characterization and purification of the small 28,000-dalton mammalian heat shock protein.

1987 • 263 citations

Dissociation as a result of phosphorylation of an aggregated form of the small stress protein, hsp27

1994 • 246 citations

Phorbol ester, calcium ionophore, or serum added to quiescent rat embryo fibroblast cells all result in the elevated phosphorylation of two 28,000-dalton mammalian stress proteins.

1985 • 233 citations

Immunoreactive αA crystallin in rat non-lenticular tissues detected with a sensitive immunoassay method

1991 • 220 citations

Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin.

1994 • 217 citations

The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2

1993 • 196 citations

Tissue distribution and developmental profiles of immunoreactive αB crystallin in the rat determined with a sensitive immunoassay system

1991 • 193 citations

Copurification of small heat shock protein with alpha B crystallin from human skeletal muscle.

1992 • 184 citations

The Amino‐Acid Sequence of the αB₂ Chain of Bovine α‐Crystallin

1974 • 182 citations

Conjugation of Glucose Oxidase from Aspergillus niger and Rabbit Antibodies Using N-Hydroxysuccinimide Ester of N-(4-Carboxycyclohexylmethyl)-Maleimide

1979 • 181 citations

cAMP-dependent phosphorylation of bovine lens alpha-crystallin.

1985 • 171 citations

α‐Crystallin Stabilizes Actin Filaments and Prevents Cytochalasin‐Induced Depolymerization in a Phosphorylation‐Dependent Manner

1996 • 166 citations

Phosphorylation of HSP27 during development and decay of thermotolerance in Chinese hamster cells

1991 • 150 citations

Alpha-crystallin/small heat shock protein has autokinase activity.

1994 • 138 citations

Okadaic acid mimics multiple changes in early protein phosphorylation and gene expression induced by tumor necrosis factor or interleukin-1.

1992 • 138 citations

Human αB-crystallin gene and preferential promoter function in lens

1990 • 126 citations

Tumor Necrosis Factor Induces the Rapid Phosphorylation of the Mammalian Heat Shock Protein hsp28

1990 • 125 citations

Cellular Stresses and Cytokines Activate Multiple Mitogen‐Activated‐Protein Kinase Kinase Homologues in PC12 and KB Cells

1996 • 123 citations

Cardiac alpha-crystallin

1990 • 95 citations

Phosphorylation of the small heat-shock protein is regulated by interleukin 1, tumour necrosis factor, growth factors, bradykinin and ATP

1991 • 91 citations

The phosphorylation sites of the B2 chain of bovine α-crystallin

1987 • 77 citations

The in vivo phosphorylation sites of bovine αB‐crystallin

1989 • 73 citations

Identification of the posttranslational modifications of bovine lens αB‐crystallins by mass spectrometry

1992 • 65 citations

Induction of the Synthesis of hsp27 and αB Crystallin in Tissues of Heat-Stressed Rats and Its Suppression by Ethanol or an α1-Adrenergic Antagonist1

1995 • 58 citations

Definition and comparison of the phosphorylation sites of the A and B chains of bovine α-crystallin

1988 • 58 citations

Translocation and induction of αB crystallin by heat shock in rat glioma (GA-1) cells

1992 • 55 citations

αB‐Crystallin is expressed in kidney epithelial cell lines and not in fibroblasts

1989 • 44 citations

Phosphorylation of α-crystallin in rat lenses is stimulated by H2O2 but phosphorylation has no effect on chaperone activity

1995 • 41 citations

Capillary column high-performance liquid chromatographic-electrospray ionization triple-stage quadrupole mass spectrometric analysis of proteins separated by two-dimensional polyacrylamide gel electrophoresis application to cerebellar protein mapping

1996 • 20 citations

Rapid phosphorylation of 28‐kDa heat‐shock protein by treatment with okadaic acid and phorbol ester of BALB/MK‐2 mouse kerationocytes

1993 • 14 citations

αB Crystallin Is Constitutively Expressed in Cultures of Bovine Articular Chondrocytes

1995 • 11 citations