Inducible control of transgene expression with ecdysone receptor: gene switches with high sensitivity, robust expression, and reduced size

NEW INSECTICIDES WITH ECDYSTEROIDAL AND JUVENILE HORMONE ACTIVITY

1998 • 884 citations

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

1996 • 858 citations

Ecdysone receptors and their biological actions

2000 • 564 citations

Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein.

1990 • 428 citations

Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential

1997 • 338 citations

Three Functional Classes of Transcriptional Activation Domains

1996 • 267 citations

Gene therapy progress and prospects: transcription regulatory systems

2004 • 130 citations

Basal promoter elements as a selective determinant of transcriptional activator function

1995 • 116 citations

High level transactivation by a modified Bombyx ecdysone receptor in mammalian cells without exogenous retinoid X receptor

1998 • 97 citations

Improved ecdysone receptor‐based inducible gene regulation system

2003 • 94 citations

Adenovirus-Mediated Inducible Gene Expression in Vivo by a Hybrid Ecdysone Receptor

2000 • 91 citations

Exploiting Internal Ribosome Entry Sites in Gene Therapy Vector Design

2004 • 87 citations

Functional Characterization of the Internal Ribosome Entry Site of eIF4G mRNA

1998 • 79 citations

A single point mutation in ecdysone receptor leads to increased ligand specificity: Implications for gene switch applications

2002 • 63 citations

Improved co-expression of multiple genes in vectors containing internal ribosome entry sites (IRESes) from human genes

2002 • 61 citations

Highly Flexible Ligand Binding Pocket of Ecdysone Receptor

2004 • 49 citations

A novel tetracycline-dependent transactivator with E2F4 transcriptional activation domain

2001 • 43 citations

A Minimal Transcription Activation Domain Consisting of a Specific Array of Aspartic Acid and Leucine Residues

1994 • 41 citations

Ecdysone-controlled expression of transgenes

2002 • 24 citations

Bicistronic Expression of Ecdysone-Inducible Receptors in Mammalian Cells

2001 • 23 citations