Synthesis and pharmacological evaluation of substituted naphth[1,2,3- de ]isoquinolines (dinapsoline analogues) as D 1 and D 2 dopamine receptor ligands

Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds

1995 • 12,149 citations

Multiple receptors for dopamine

1979 • 3,739 citations

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1990 • 2,630 citations

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1991 • 2,008 citations

The Palladium-Catalyzed Cross-Coupling Reaction of Phenylboronic Acid with Haloarenes in the Presence of Bases

1981 • 1,817 citations

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

1991 • 1,157 citations

Molecular cloning and expression of the gene for a human D1 dopamine receptor

1990 • 675 citations

Review: D1 dopamine receptor—the search for a function: A critical evaluation of the D1/D2 dopamine receptor classification and its functional implications

1987 • 664 citations

Multiple D2 dopamine receptors produced by alternative RNA splicing

1989 • 642 citations

Pyridine-derived triflating reagents: An improved preparation of vinyl triflates from metallo enolates.

1992 • 500 citations

Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor.

1991 • 359 citations

Glutamate/dopamine D₁/D₂ balance in the basal ganglia and its relevance to Parkinson' disease

1995 • 216 citations

Dopamine receptors: Pharmacological and anatomical evidences indicate that two distinct dopamine receptor populations are present in rat striatum

1978 • 203 citations

Pivotal role for aspartate-80 in the regulation of dopamine D2 receptor affinity for drugs and inhibition of adenylyl cyclase.

1991 • 185 citations

Trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine: a highly potent selective dopamine D1 full agonist

1990 • 171 citations

SCH-23390: A selective D1 dopamine antagonist with potent D2 behavioral actions

1984 • 158 citations

Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-ioduced parkinsonism in monkeys

1991 • 137 citations

ABT-431, a D1 receptor agonist prodrug, has efficacy in Parkinson's disease

1999 • 108 citations

Dihydrexidine, a novel selective high potency full dopamine D-1 receptor agonist

1989 • 106 citations

Homologous desensitization of the D1A dopamine receptor: efficacy in causing desensitization dissociates from both receptor occupancy and functional potency.

1998 • 83 citations

Effects of the full dopamine D1 receptor agonist dihydrexidine in Parkinson's disease.

1998 • 82 citations

Conformational Analysis of D₁ Dopamine Receptor Agonists: Pharmacophore Assessment and Receptor Mapping

1996 • 65 citations

8,9-Dihydroxy-2,3,7,11b-tetrahydro-1H-naph[1,2,3-de]isoquinoline: A Potent Full Dopamine D₁ Agonist Containing a Rigid β-Phenyldopamine Pharmacophore

1996 • 55 citations

Regulation and functional characterization of a rat recombinant dopamine D3 receptor

1995 • 50 citations

Quantification of D1B (D5) receptors in dopamine D1A receptor-deficient mice

2001 • 49 citations

Dinapsoline: characterization of a D1 dopamine receptor agonist in a rat model of Parkinson's disease.

2001 • 47 citations

(+)-Dinapsoline: An Efficient Synthesis and Pharmacological Profile of a Novel Dopamine Agonist

2002 • 42 citations

Molecular cloning and expression of the rhesus macaque D1 dopamine receptor gene.

1992 • 37 citations

Hexahydrobenzo[a]phenanthridines: novel dopamine D3 receptor ligands

1993 • 30 citations

Synthesis and Biological Evaluation of a Series of Substituted Benzo[a]phenanthridines as Agonists at D1 and D2 Dopamine Receptors

1995 • 24 citations

Alternative Formal Synthesis of the Potent D₁ Dopamine Agonist Dihydroxy-2,3,7,11b-tetrahydro-1H- naphth[1,2,3-de]isoquinoline: Dinapsoline

1999 • 11 citations

Multiple tritium labelling of (+)‐7‐chloro‐8‐hydroxy‐1‐phenyl‐3‐methyl‐2,3,4,5‐tetrahydro‐1hZ‐3‐benzazepine (sch23390)

1986 • 8 citations