Brain-Derived Neurotrophic Factor Stimulates Hindlimb Stepping and Sprouting of Cholinergic Fibers after Spinal Cord Injury

Statistical Principles in Experimental Design

1992 • 4,547 citations

A Sensitive and Reliable Locomotor Rating Scale for Open Field Testing in Rats

1995 • 4,199 citations

Neurotrophins and Neuronal Plasticity

1995 • 1,937 citations

Graded Histological and Locomotor Outcomes after Spinal Cord Contusion Using the NYU Weight-Drop Device versus Transection

1996 • 1,440 citations

Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus

1995 • 1,354 citations

Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors

1990 • 1,232 citations

Degeneration and regeneration of axons in the lesioned spinal cord

1996 • 1,123 citations

Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion

1994 • 912 citations

Neuronal and Glial Apoptosis after Traumatic Spinal Cord Injury

1997 • 901 citations

Recovery of locomotion after chronic spinalization in the adult cat

1987 • 835 citations

Neurotrophic factors: from molecule to man

1994 • 800 citations

Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats

1998 • 794 citations

Central Pattern Generators for Locomotion, with Special Reference to Vertebrates

1985 • 771 citations

Spinal Cord Repair in Adult Paraplegic Rats: Partial Restoration of Hind Limb Function

1996 • 764 citations

Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death

1992 • 668 citations

Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors.

1995 • 612 citations

Human Lumbosacral Spinal Cord Interprets Loading During Stepping

1997 • 595 citations

Neurotrophin-3 and Brain-Derived Neurotrophic Factor Induce Oligodendrocyte Proliferation and Myelination of Regenerating Axons in the Contused Adult Rat Spinal Cord

1998 • 578 citations

Inhibition of Ocular Dominance Column Formation by Infusion of NT-4/5 or BDNF

1995 • 572 citations

Neurotrophins and brain insults

1994 • 564 citations

Axonal regeneration into Schwann cell‐seeded guidance channels grafted into transected adult rat spinal cord

1995 • 529 citations

A Combination of BDNF and NT-3 Promotes Supraspinal Axonal Regeneration into Schwann Cell Grafts in Adult Rat Thoracic Spinal Cord

1995 • 482 citations

Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain

1995 • 470 citations

Neurotrophic Factors Increase Axonal Growth after Spinal Cord Injury and Transplantation in the Adult Rat

1997 • 360 citations

Treatment of the Chronically Injured Spinal Cord with Neurotrophic Factors Can Promote Axonal Regeneration from Supraspinal Neurons

1997 • 344 citations

The locomotion of the acute spinal cat injected with clonidine i.v.

1973 • 341 citations

Initiation and modulation of the locomotor pattern in the adult chronic spinal cat by noradrenergic, serotonergic and dopaminergic drugs

1991 • 326 citations

Brain-Derived Neurotrophic Factor Protects against Ischemic Cell Damage in Rat Hippocampus

1994 • 326 citations

Intraventricular Brain-Derived Neurotrophic Factor Reduces Infarct Size after Focal Cerebral Ischemia in Rats

1997 • 326 citations

Blockade of Endogenous Ligands of TrkB Inhibits Formation of Ocular Dominance Columns

1997 • 309 citations

Endogenous Neuroprotection Factors and Traumatic Brain Injury: Mechanisms of Action and Implications for Therapy

1994 • 308 citations

Characterization of glial trkB receptors: differential response to injury in the central and peripheral nervous systems.

1993 • 259 citations

Spinal Cord Injury Produced by Consistent Mechanical Displacement of the Cord in Rats: Behavioral and Histologic Analysis

1992 • 247 citations

A behavioral and anatomical analysis of spinal cord injury produced by a feedback-controlled impaction device

1987 • 231 citations

BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration

1996 • 231 citations

Chapter 22 Response of rubrospinal and corticospinal neurons to injury and neurotrophins

1994 • 227 citations

Restoration of function by replacement of spinal cord segments in the rat

1994 • 214 citations

Distribution of Intracerebral Ventricularly Administered Neurotrophins in Rat Brain and Its Correlation with Trk Receptor Expression

1994 • 213 citations

Brain-Derived Neurotrophic Factor and Neurotrophin-4/5 Stimulate Growth of Axonal Branches from Regenerating Retinal Ganglion Cells

1996 • 206 citations

BDNF and NT-4/5 exert neurotrophic influences on injured adult spinal motor neurons

1995 • 204 citations

Neurotrophic Factors in Central Nervous System Trauma

1995 • 204 citations

BDN F Down‐regulates Neurotrophin Responsiveness, TrkB Protein and TrkB mRNA Levels in Cultured Rat Hippocampal Neurons

1996 • 199 citations

The mesencephalic locomotor region. I. Activation of a medullary projection site

1987 • 197 citations

BDNF Prevents and Reverses Adult Rat Motor Neuron Degeneration and Induces Axonal Outgrowth

1997 • 194 citations

Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo

1997 • 186 citations

Differential distribution of exogenous BDNF, NGF, and NT‐3 in the brain corresponds to the relative abundance and distribution of high‐affinity and low‐affinity neurotrophin receptors

1995 • 170 citations

Fetal grafts alter chronic behavioral outcome after contusion damage to the adult rat spinal cord

1992 • 167 citations

Pathology of Spinal Injuries

1984 • 156 citations

Expression of mRNAs for neurotrophin receptors in the dorsal root ganglion and spinal cord during development and following peripheral or central axotomy

1993 • 155 citations

The biological responses of axotomized adult motoneurons to brain- derived neurotrophic factor

1994 • 148 citations

Experimental Analysis of Progressive Necrosis after Spinal Cord Trauma in the Rat: Etiological Role of the Inflammatory Response

1997 • 146 citations

Are Neurotrophins Synaptotrophins?

1996 • 134 citations

Spinal cord stimulation-induced locomotion in the adult cat

1992 • 133 citations

An Electromechanical Spinal Injury Technique with Dynamic Sensitivity

1992 • 114 citations

Intrastriatal Infusions of Brain-Derived Neurotrophic Factor: Retrograde Transport and Colocalization with Dopamine Containing Substantia Nigra Neurons in Rat

1994 • 104 citations

Effects of BDNF Infusion on the Regulation of TrkB Protein and Message in Adult Rat Brain

1997 • 101 citations

Further characterization of the effects of brain‐derived neurotrophic factor and ciliary neurotrophic factor on axotomized neonatal and adult mammalian motor neurons

1994 • 99 citations

Astrocytic and neuronal factors affecting axon regeneration in the damaged central nervous system

1997 • 97 citations

Neurotrophic factors prevent the death of CNS neurons after spinal cord lesions in newborn rats

1994 • 95 citations

Treatment with genetically engineered fibroblasts producing NGF or BDNF can accelerate recovery from traumatic spinal cord injury in the adult rat

1996 • 92 citations

Potential of adult mammalian lumbosacral spinal cord to execute and acquire improved locomotion in the absence of supraspinal input.

1992 • 91 citations

Brain-derived neurotrophic factor increases the electrical activity of pars compacta dopamine neurons in vivo.

1994 • 86 citations

A light and electron microscopic study of intracellularly HRP‐labeled lumbar motoneurons after intramedullary axotomy in the adult cat

1992 • 80 citations

Pharmacokinetics of Intrathecally Applied BDNF and Effects on Spinal Motoneurons

1996 • 80 citations

Selective role for trkB neurotrophin receptors in rapid modulation of hippocampal synaptic transmission

1996 • 71 citations

Brain-derived neurotrophic factor reduces necrotic zone and supports neuronal survival after spinal cord hemisection in adult rats

1996 • 67 citations

Does Motor Learning Occur in the Spinal Cord?

1997 • 66 citations

Central infusions of brain-derived neurotrophic factor and , but not nerve growth factor and neurotrophin-3, prevent loss of the cholinergic phenotype in injured adult motor neurons

1996 • 61 citations

Functional analysis of an electromechanical spinal cord injury device

1987 • 57 citations

l-DOPA-induced air-stepping in developing rats

1991 • 54 citations

Pharmacology of Locomotion: An Account of Studies in Spinal Cats and Spinal Cord Injured Subjects

1993 • 45 citations

l-DOPA-induced air-stepping in decerebrate developing rats

1991 • 39 citations

Neurotoxic injury in rat hippocampus differentially affects multiple trkB and trkC transcripts

1995 • 16 citations