Penicillanic acid sulfone: nature of irreversible inactivation of the RTEM .beta.-lactamase from Escherichia coli

Rapid chromatographic technique for preparative separations with moderate resolution

1978 • 5,766 citations

The Preparation and Enzymatic Hydrolysis of Reduced and S-Carboxymethylated Proteins

1963 • 2,600 citations

Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.

1978 • 791 citations

Penicillinase Synthesis Controlled By Infectious R Factors In Enterobacteriaceae

1965 • 555 citations

Glutaraldehyde as a protein cross-linking reagent

1968 • 542 citations

Naturally-occurring .BETA.-lactamase inhibitors with antibacterial activity.

1976 • 388 citations

Suicide enzyme inactivators

1976 • 366 citations

.beta.-Lactamase proceeds via an acyl-enzyme intermediate. Interaction of the Escherichia coli RTEM enzyme with cefoxitin

1980 • 222 citations

Kinetic studies on the inactivation of Escherichia coli RTEM β-lactamase by clavulanic acid

1978 • 204 citations

Analytical isoelectric focusing of R factor-determined beta-lactamases: correlation with plasmid compatibility

1976 • 172 citations

Chemistry of Cephalosporin Antibiotics. III. Chemical Correlation of Penicillin and Cephalosporin Antibiotics

1963 • 141 citations

Penicillinase active sites: Labelling of serine‐44 in β‐lactamase I by 6β‐bromopenicillanic acid

1979 • 129 citations

Penicillanic acid sulfone: an unexpected isotope effect in the interaction of 6.alpha.- and 6.beta.-monodeuterio and of 6,6-dideuterio derivatives with RTEM .beta.-lactamase from Escherichia coli. Crystal structure of penicillanic acid sulfone

1981 • 107 citations

Inactivation of Bacillus cereus .beta.-lactamase I by 6.beta.-bromopenicillanic acid: kinetics

1980 • 105 citations

6-beta-bromopenicillanic acid, a potent beta-lactamase inhibitor.

1978 • 105 citations

A semi-synthetic penicillinase inactivator

1979 • 91 citations

Absorption Spectra of Some 2,4-Dinitrophenylhydrazones

1946 • 82 citations

6 β-Bromopenicillanic acid inactivates β-lactamase I

1979 • 75 citations

Inactivation of radiolabeled RTEM .beta.-lactamase from Escherichia coli by clavulanic acid and 9-deoxyclavulanic acid

1981 • 67 citations

Structural studies on penicillin derivatives. V. Penicillin sulfoxide-sulfenic acid equilibrium

1970 • 54 citations

Penicillanic acid sulfone: interaction with RTEM .beta.-lactamase from Escherichia coli at different pH values

1981 • 53 citations

Enzymatic Conversion of β-Hydroxypropionate to Malonic Semialdehyde

1959 • 51 citations

Kinetics of inactivation of β-lactamase I by 6 β-bromopenicillanic acid

1980 • 35 citations

6-Chloro- and 6-Bromopenicillanic Acids

1962 • 34 citations

Synthesis of tritium-labelled isopenicillin N, penicillin N and 6-aminopenicillanic acid

1975 • 24 citations

Die Struktur der isomeren β‐Benzylaminocrotonsäure‐äthylester

1955 • 22 citations

On the chemical binding of 6β-bromopenicillanic acid to β-lactamase I

1979 • 14 citations

Clavulanic acid. Rearrangement to 3, 4-disubstituted pyrroles

1982 • 12 citations

Synthesis of (.BETA.-methyl-3H)-benzylpenicillin and (.BETA.-methyl-3H)-6-aminopenicillanic acid.

1976 • 11 citations

The inactivation of Bacillus cereus 569/H .BETA.-lactamase by 6-.BETA.-(trifluoromethanesulfonyl)amidopenicillanic acid sulfone: pH dependence and stoichiometry.

1982 • 8 citations