Distinctive role of CCR7 in migration and functional activity of naive‐ and effector/memory‐like Treg subsets

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

2005 • 2,667 citations

CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs

1999 • 2,326 citations

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

2005 • 2,256 citations

Natural versus adaptive regulatory T cells

2003 • 1,363 citations

Suppressor Effector Function of CD4+CD25+ Immunoregulatory T Cells Is Antigen Nonspecific

2000 • 1,282 citations

Chemokines and Cell Migration in Secondary Lymphoid Organs

1999 • 1,046 citations

Unique Chemotactic Response Profile and Specific Expression of Chemokine Receptors Ccr4 and Ccr8 by Cd4+Cd25+ Regulatory T Cells

2001 • 888 citations

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

2005 • 783 citations

Developmental Stage, Phenotype, and Migration Distinguish Naive- and Effector/Memory-like CD4+ Regulatory T Cells

2004 • 618 citations

Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics

2005 • 489 citations

Expression of the integrin α_Eβ₇identifies unique subsets of CD25⁺as well as CD25⁻regulatory T cells

2002 • 476 citations

Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues

2005 • 458 citations

Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD

2004 • 420 citations

Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion

2006 • 407 citations

The Subpopulation of CD4+CD25+ Splenocytes That Delays Adoptive Transfer of Diabetes Expresses L-Selectin and High Levels of CCR7

2002 • 383 citations

Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor

2005 • 371 citations

L-Selectinhi but not the L-selectinlo CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection

2004 • 360 citations

CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T-cell subset

2004 • 314 citations

A peripheral circulating compartment of natural naive CD4+ Tregs

2005 • 299 citations

T-cell homing specificity and plasticity: new concepts and future challenges

2006 • 298 citations

The Majority of Human Peripheral Blood CD4+CD25highFoxp3+ Regulatory T Cells Bear Functional Skin-Homing Receptors

2006 • 278 citations

Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

2005 • 266 citations

Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo

2005 • 250 citations

Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease

2005 • 243 citations

CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence

2006 • 224 citations

Homing to suppress: address codes for Treg migration

2005 • 180 citations

Human CD25⁺ regulatory T cells: two subsets defined by the integrins α₄β₇ or α₄β₁ confer distinct suppressive properties upon CD4⁺ T helper cells

2004 • 172 citations

IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin

2006 • 170 citations

Epithelial Inflammation Is Associated with CCL28 Production and the Recruitment of Regulatory T Cells Expressing CCR10

2006 • 170 citations

Regulation of Trafficking Receptor Expression in Human Forkhead Box P3+ Regulatory T Cells

2006 • 161 citations

Induction of organ‐selective CD4⁺ regulatory T cell homing

2007 • 158 citations

FoxP3+ T Cells Undergo Conventional First Switch to Lymphoid Tissue Homing Receptors in Thymus but Accelerated Second Switch to Nonlymphoid Tissue Homing Receptors in Secondary Lymphoid Tissues

2007 • 123 citations

Skin‐versus gut‐skewed homing receptor expression and intrinsic CCR4 expression on human peripheral blood CD4⁺CD25⁺ suppressor T cells

2003 • 112 citations

Impact of CCR7 on Priming and Distribution of Antiviral Effector and Memory CTL

2004 • 86 citations

Skin‐homing CLA⁺T cells and regulatory CD25⁺T cells represent major subsets of human peripheral blood memory T cells migrating in response to CCL1/I‐309

2002 • 83 citations

In Vivo Differentiated Cytokine-Producing CD4+ T Cells Express Functional CCR7

2002 • 82 citations

Skin-homing CLA+ T cells and regulatory CD25+ T cells represent major subsets of human peripheral blood memory T cells migrating in response to CCL1/I-309

2002 • 82 citations

Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection

2005 • 67 citations

Tissue targeting of T cells by DCs and microenvironments

2004 • 64 citations

The chemokine receptor CCR7 controls lymph node‐dependent cytotoxic T cell priming in alloimmune responses

2004 • 60 citations

CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity

2006 • 60 citations

Migration and function of FoxP3+ regulatory T cells in the hematolymphoid system

2006 • 58 citations

CC Chemokine Receptor 7 Expression by Effector/Memory CD4⁺T Cells Depends on Antigen Specificity and Tissue Localization during Influenza A Virus Infection

2004 • 57 citations