The hepatitis B virus protein MHBs(t) sensitizes hepatoma cells to TRAIL-induced apoptosis through ERK2

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

1995 • 5,334 citations

Identification and characterization of a new member of the TNF family that induces apoptosis

1995 • 2,890 citations

Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

1999 • 2,494 citations

Safety and antitumor activity of recombinant soluble Apo2 ligand

1999 • 2,215 citations

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

1997 • 1,694 citations

An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

1997 • 1,506 citations

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL

1997 • 1,119 citations

Requirement for ERK Activation in Cisplatin-induced Apoptosis

2000 • 664 citations

Essential roles of the Fas ligand in the development of hepatitis

1997 • 483 citations

p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha.

1998 • 363 citations

MAPK/ERK Overrides the Apoptotic Signaling from Fas, TNF, and TRAIL Receptors

2001 • 337 citations

TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

1997 • 331 citations

TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling

1998 • 327 citations

Characterization of two receptors for TRAIL¹

1997 • 293 citations

TRAIL/Apo-2-ligand-induced apoptosis in human T cells

1998 • 273 citations

Perforin, Fas/Fas ligand, and TNF-alpha pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL.

1997 • 256 citations

MEK Inhibition Enhances Paclitaxel-induced Tumor Apoptosis

2000 • 222 citations

The PreS2 activator MHBst of hepatitis B virus activates c-raf-1/Erk2 signaling in transgenic mice

2002 • 162 citations

Disparate roles for TNF-alpha and Fas ligand in concanavalin A-induced hepatitis.

1998 • 159 citations

Critical roles of TRAIL in hepatic cell death and hepatic inflammation

2004 • 154 citations

Disparate Roles for TNF-α and Fas Ligand in Concanavalin A-Induced Hepatitis

1998 • 150 citations

Critical roles of TRAIL in hepatic cell death and hepatic inflammation

2004 • 146 citations

Involvement of TRAIL and its receptors in viral hepatitis

2002 • 145 citations

Respiratory Syncytial Virus Infection Sensitizes Cells to Apoptosis Mediated by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand

2003 • 132 citations

Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to apo2l/trail‐induced apoptosis

2002 • 130 citations

Inhibition of TRAIL-Induced Apoptosis and Forced Internalization of TRAIL Receptor 1 by Adenovirus Proteins

2001 • 114 citations

The Human Papillomavirus Type 16 E5 Protein Impairs TRAIL- and FasL-Mediated Apoptosis in HaCaT Cells by Different Mechanisms

2002 • 110 citations

Hepatitis B Virus Sensitizes Hepatocytes to TRAIL-Induced Apoptosis through Bax

2007 • 101 citations

PG490-mediated sensitization of lung cancer cells to Apo2L/TRAIL-induced apoptosis requires activation of ERK2

2003 • 91 citations

Induction and regulation of tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand-mediated apoptosis in renal cell carcinoma.

2002 • 80 citations

The hepatitis B virus pre-S/S(t) transactivator is generated by 3' truncations within a defined region of the S gene

1992 • 67 citations

Characterization of essential domains for the functionality of the MHBst transcriptional activator and identification of a minimal MHBst activator.

1995 • 65 citations

Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells.

2001 • 64 citations

Caspase 8-dependent sensitization of cancer cells to TRAIL-induced apoptosis following reovirus-infection

2001 • 63 citations

Enhanced tumor killing by Apo2L/TRAIL and CPT-11 co-treatment is associated with p21 cleavage and differential regulation of Apo2L/TRAIL ligand and its receptors

2002 • 50 citations

Fas-Fas Ligand Interactions Play a Major Role in Effector Functions of Cytotoxic T Lymphocytes after Adenovirus Vector-Mediated Gene Transfer

1999 • 34 citations

Blockade of TRAIL pathway ameliorates HBV-induced hepatocyte apoptosis in an acute hepatitis model

2006 • 30 citations

A new hypothesis of pathogenetic mechanism of viral hepatitis B and C

2001 • 26 citations

Enhanced TRAIL sensitivity by E1A expression in human cancer and normal cell lines: inhibition by adenovirus E1B19K and E3 proteins

2004 • 17 citations

Intracellular Accumulation of Middle Hepatitis B Surface Protein Activates Gene Transcription

2001 • 8 citations

Hepatitis B virus X protein modulates the apoptosis of hepatoma cell line induced by TRAIL

2005 • 5 citations