A novel enzyme from bovine neurointermediate pituitary catalyzes dealkylation of .alpha.-hydroxyglycine derivatives, thereby functioning sequentially with peptidylglycine .alpha.-amidating monooxygenase in peptide amidation

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Mechanism of C-terminal amide formation by pituitary enzymes

1982 • 658 citations

Identification in pituitary tissue of a peptide alpha-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid.

1983 • 363 citations

Peptide α-Amidation

1988 • 241 citations

The Enzymology and Intracellular Organization of Peptide Precursor Processing: The Secretory Vesicle Hypothesis

1985 • 194 citations

Purification and characterization of peptidylglycine alpha-amidating monooxygenase from bovine neurointermediate pituitary.

1986 • 169 citations

Structure of the Precursor to an Enzyme Mediating COOH-Terminal Amidation in Peptide Biosynthesis

1987 • 163 citations

Alternative mRNA splicing generates multiple forms of peptidyl-glycine alpha-amidating monooxygenase in rat atrium.

1989 • 116 citations

Enzymatic peptidyl .alpha.-amidation proceeds through formation of an .alpha.-hydroxyglycine intermediate

1989 • 103 citations

Novel substrates and inhibitors of peptidylglycine .alpha.-amidating monooxygenase

1990 • 101 citations

Biosynthesis of the C-terminal amide in peptide hormones

1987 • 88 citations

Tissue Specific Expression of Rat Peptidylglycine α-Amidating Monooxygenase Activity and mRNA

1989 • 78 citations

Peptide C-terminal α-amidating enzyme purified to homogeneity from Xenopuslaevis skin

1986 • 77 citations

Cloning and sequence of cDNA encoding a peptide C-terminal α-amidating enzyme from Xenopuslaevis

1987 • 71 citations

Purification and Characterization of a Peptidyl Glycine Monooxygenase from Porcine Pituitary*

1986 • 66 citations

Cloning of cDNA encoding a new peptide C-terminal α-amidating enzyme having a putative membrane-spanning domain from Xenopuslaevis skin

1988 • 66 citations

Membrane-associated peptidylglycine alpha-amidating monooxygenase in the heart.

1988 • 63 citations

Formation of peptide amides by peptidylglycine .alpha.-amidating monooxygenase: a new assay and stereochemistry of hydrogen loss

1988 • 55 citations

Purification of a peptidylglycine α-amidating enzyme from transplantable rat medullary thyroid carcinomas

1988 • 46 citations

Rat peptidylglycine α-amidating enzyme: The relation between activities at neutral and alkaline pH values

1989 • 25 citations

A new facile trinitrophenylated substrate for peptide α-amidation and its use to characterize PAM activity in chromaffin granules

1988 • 21 citations