Biosynthesis of the C-terminal amide in peptide hormones

Identification in pituitary tissue of a peptide alpha-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid.

1983 • 363 citations

Purification and characterization of peptidylglycine alpha-amidating monooxygenase from bovine neurointermediate pituitary.

1986 • 169 citations

Translation of melittin messenger RNA in vitro yields a product terminating with glutaminylglycine rather than with glutaminamide.

1977 • 104 citations

Biogenetics of neurohormonal peptides

1986 • 86 citations

Substrate specificity of an amidating enzyme in porcine pituitary

1983 • 82 citations

Peptide C-terminal α-amidating enzyme purified to homogeneity from Xenopuslaevis skin

1986 • 77 citations

Characterization of a peptide alpha-amidation activity from rat anterior pituitary.

1984 • 76 citations

Role of ascorbic acid in dopamine beta-hydroxylation. The endogenous enzyme cofactor and putative electron donor for cofactor regeneration.

1986 • 74 citations

Hormonal, Drug, and Dietary Factors Affecting Peptidyl Glycineα-Amidating Monooxygenase Activity in Various Tissues of the Adult Male Rat*

1985 • 72 citations

Cloning and sequence of cDNA encoding a peptide C-terminal α-amidating enzyme from Xenopuslaevis

1987 • 71 citations

Purification and Characterization of a Peptidyl Glycine Monooxygenase from Porcine Pituitary*

1986 • 66 citations

Enzyme‐catalysed peptide amidation

1987 • 65 citations

Inhibition of peptide amidation by disulfiram and diethyldithiocarbamate.

1986 • 61 citations

Formation of the COOH‐terminal amide group of thyrotropin‐releasing‐factor

1983 • 58 citations

Hypothalamic peptidyl-glycine alpha-amidating monooxygenase: preliminary characterization

1984 • 58 citations

Regulation of peptide amidation in cultured pituitary cells.

1985 • 50 citations

The amidating enzyme in pituitary will accept a peptide with c-terminal d-alanine as substrate

1983 • 49 citations

Detection and partial characterization of an amidating enzyme in skin secretion of Xenopus laevis

1986 • 29 citations

Further characterization of the peptidyl α-amidating enzyme in rat anterior pituitary secretory granules

1985 • 28 citations

C‐terminal amidation of neuropeptides

1984 • 25 citations

Regulation of bioactive β‐endorphin processing in rat pars intermedia

1984 • 23 citations

Evidence for high peptide α-amidation activity in the neonatal rat pancreas

1986 • 16 citations

The Characterization of the Ascorbic Acid-Mediatedα-Amidation ofα-Melanotropin in Cultured Intermediate Pituitary Lobe Cells*

1986 • 14 citations

Post-translational processing in Xenopus oocytes includes carboxyl-terminal amidation.

1986 • 11 citations

A rapid, sensitive assay for glycine-directed amidating enzymes

1985 • 7 citations

Sequential processing reactions in the formation of hormone amides

1987 • 7 citations

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