Diffusion MRI in multiple sclerosis

Voxel-Based Morphometry—The Methods

2000 • 8,281 citations

Microstructural and Physiological Features of Tissues Elucidated by Quantitative-Diffusion-Tensor MRI

1996 • 4,247 citations

Estimation of the Effective Self-Diffusion Tensor from the NMR Spin Echo

1994 • 3,599 citations

Diffusion tensor imaging: Concepts and applications

2001 • 3,375 citations

Diffusion tensor MR imaging of the human brain.

1996 • 2,621 citations

Fiber tracking: principles and strategies – a technical review

2002 • 1,993 citations

Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis

1998 • 652 citations

Diffraction-like effects in NMR diffusion studies of fluids in porous solids

1991 • 644 citations

Diffusion tensor imaging of lesions and normal-appearing white matter in multiple sclerosis

1999 • 614 citations

Imaging cortical association tracts in the human brain using diffusion‐tensor‐based axonal tracking

2002 • 564 citations

Diffusion tensor magnetic resonance imaging in multiple sclerosis

2001 • 543 citations

Characterization of anisotropy in high angular resolution diffusion‐weighted MRI

2002 • 517 citations

Primary progressive multiple sclerosis

1997 • 505 citations

Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis

2000 • 404 citations

Anisotropy in high angular resolution diffusion‐weighted MRI

2001 • 390 citations

Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis

1993 • 378 citations

A histological, histochemical and biochemical study of the macroscopically normal white matter in multiple sclerosis

1979 • 357 citations

Investigation of MS normal-appearing brain using diffusion tensor MRI with clinical correlations

2001 • 345 citations

Size-selective neuronal changes in the anterior optic pathways suggest a differential susceptibility to injury in multiple sclerosis

2001 • 320 citations

Statistical artifacts in diffusion tensor MRI (DT-MRI) caused by background noise

2000 • 315 citations

The pathogenesis of lesions and normal-appearing white matter changes in multiple sclerosis: A serial diffusion MRI study

2000 • 314 citations

Quantitative MRI of the brain : measuring changes caused by disease

2003 • 314 citations

Magnetisation transfer ratio and mean diffusivity of normal appearing white and grey matter from patients with multiple sclerosis

2001 • 289 citations

High field MRI correlates of myelin content and axonal density in multiple sclerosis

2003 • 275 citations

Magnetic resonance diffusion tensor imaging for characterizing diffuse and focal white matter abnormalities in multiple sclerosis

2000 • 263 citations

Investigation of apparent diffusion coefficient and diffusion tensor anisotrophy in acute and chronic multiple sclerosis lesions.

1999 • 252 citations

Mean diffusivity and fractional anisotropy histograms of patients with multiple sclerosis.

2001 • 238 citations

High b‐value q‐space analyzed diffusion‐weighted MRI: Application to multiple sclerosis

2001 • 233 citations

Magnetic resonance studies of abnormalities in the normal appearing white matter and grey matter in multiple sclerosis

2003 • 232 citations

Assessment of Normal-Appearing White and Gray Matter in Patients With Primary Progressive Multiple Sclerosis

2002 • 220 citations

Cognitive dysfunction in patients with mildly disabling relapsing–remitting multiple sclerosis: an exploratory study with diffusion tensor MR imaging

2002 • 217 citations

A Quantitative Study of Water Diffusion in Multiple Sclerosis Lesions and Normal-Appearing White Matter Using Echo-Planar Imaging

2000 • 214 citations

Quantification of brain gray matter damage in different MS phenotypes by use of diffusion tensor MR imaging.

2002 • 194 citations

Multiple Sclerosis: Diffusion Tensor MR Imaging for Evaluation of Normal-appearing White Matter

2002 • 189 citations

Apparent diffusion coefficients in benign and secondary progressive multiple sclerosis by nuclear magnetic resonance

1996 • 188 citations

Pathologic damage in MS assessed by diffusion-weighted and magnetization transfer MRI

2000 • 185 citations

A method for obtaining tract-specific diffusion tensor MRI measurements in the presence of disease: application to patients with clinically isolated syndromes suggestive of multiple sclerosis

2005 • 180 citations

A study of the mechanisms of normal-appearing white matter damage in multiple sclerosis using diffusion tensor imaging

2003 • 174 citations

Optic nerve diffusion tensor imaging in optic neuritis

2005 • 167 citations

Diffusion tensor fiber tracking of human brain connectivity: aquisition methods, reliability analysis and biological results

2002 • 165 citations

An error analysis of white matter tractography methods: synthetic diffusion tensor field simulations

2003 • 161 citations

Diffusion imaging of the spinal cord in vivo: Estimation of the principal diffusivities and application to multiple sclerosis

2000 • 147 citations

Comparison of multiple sclerosis clinical subgroups using navigated spin echo diffusion-weighted imaging

1999 • 140 citations

Pyramidal tract mapping by diffusion tensor magnetic resonance imaging in multiple sclerosis: improving correlations with disability

2003 • 135 citations

Mean diffusivity and fractional anisotropy histogram analysis of the cervical cord in MS patients

2005 • 133 citations

Weekly diffusion-weighted imaging of normal-appearing white matter in MS

2000 • 128 citations

Optic radiation changes after optic neuritis detected by tractography‐based group mapping

2005 • 124 citations

White matter mapping using diffusion tensor MRI

2002 • 122 citations

Multiple sclerosis: comparison of trace apparent diffusion coefficients with MR enhancement pattern of lesions.

2000 • 121 citations

Whole-brain diffusion MR histograms differ between MS subtypes

2000 • 120 citations

Short-term accrual of gray matter pathology in patients with progressive multiple sclerosis: an in vivo study using diffusion tensor MRI

2004 • 109 citations

Characterization of tissue damage in multiple sclerosis by nuclear magnetic resonance

1999 • 109 citations

Imaging of multiple sclerosis: Role in neurotherapeutics

2005 • 108 citations

Demyelinating plaques in relapsing-remitting and secondary-progressive multiple sclerosis: assessment with diffusion MR imaging.

2000 • 105 citations

Diffusion-Tensor Magnetic Resonance Imaging Detects Normal-Appearing White Matter Damage Unrelated to Short-term Disease Activity in Patients at the Earliest Clinical Stage of Multiple Sclerosis

2005 • 103 citations

Quantification of cervical cord pathology in primary progressive MS using diffusion tensor MRI

2005 • 101 citations

Progressive Gray Matter Damage in Patients With Relapsing-Remitting Multiple Sclerosis

2005 • 100 citations

Correlates of MS disability assessed in vivo using aggregates of MR quantities

2001 • 92 citations

‘Importance sampling’ in MS: Use of diffusion tensor tractography to quantify pathology related to specific impairment

2005 • 91 citations

Optic nerve diffusion measurement from diffusion-weighted imaging in optic neuritis.

2005 • 90 citations

MR correlates of cerebral atrophy in patients with multiple sclerosis

2002 • 89 citations

Correlation of multiple sclerosis measures derived from T2-weighted, T1-weighted, magnetization transfer, and diffusion tensor MR imaging

2001 • 85 citations

The use of quantitative magnetic-resonance-based techniques to monitor the evolution of multiple sclerosis

2003 • 84 citations

Diffusion Tensor Magnetic Resonance Imaging in Multiple Sclerosis

2005 • 82 citations

Diffusion tensor imaging in multiple sclerosis: a tool for monitoring changes in normal-appearing white matter

2004 • 82 citations

Diffusion tensor imaging in early relapsing-remitting multiple sclerosis

2001 • 81 citations

Quantitative Diffusion Measurements in Focal Multiple Sclerosis Lesions

2000 • 63 citations

Diffusion of water in large demyelinating lesions: a follow-up study

2002 • 61 citations

Diffusion‐ and perfusion‐weighted MR imaging in a patient with acute demyelinating encephalomyelitis (ADEM)

2002 • 56 citations

Coefficient D(av) is more sensitive than fractional anisotropy in monitoring progression of irreversible tissue damage in focal nonactive multiple sclerosis lesions.

2003 • 52 citations

Intra-voxel and inter-voxel coherence in patients with multiple sclerosis assessed using diffusion tensor MRI

2002 • 51 citations

Diffusion tensor imaging of early relapsing-remitting multiple sclerosis with histogram analysis using automated segmentation and brain volume correction

2004 • 50 citations

Magnetization transfer and diffusion tensor MR imaging of basal ganglia from patients with multiple sclerosis

2001 • 46 citations

Progressive change in primary progressive multiple sclerosis normal-appearing white matter: a serial diffusion magnetic resonance imaging study

2004 • 46 citations

Vanishing Balo-like lesions in multiple sclerosis

2000 • 31 citations

Multiple sclerosis patients and immunomodulation therapies: the potential role of new MRI techniques to assess responders versus non-responders

2005 • 8 citations