Up-regulation of human α7 nicotinic receptors by chronic treatment with activator and antagonist ligands

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons

1995 • 1,017 citations

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

1990 • 923 citations

α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells

1994 • 869 citations

Pharmacology of Nicotine: Addiction and Therapeutics

1996 • 578 citations

Nicotinic acetylcholine receptors in health and disease

1997 • 446 citations

Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family.

1987 • 431 citations

Functional contributions of α5 subunit to neuronal acetylcholine receptor channels

1996 • 389 citations

Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover.

1994 • 381 citations

Suppression of programmed neuronal death by sustained elevation of cytoplasmic calcium

1992 • 363 citations

The paradox of nicotinic acetylcholine receptor upregulation by nicotine

1990 • 350 citations

Alpha-bungarotoxin binding to hippocampal interneurons: immunocytochemical characterization and effects on growth factor expression

1993 • 205 citations

Chronic Nicotine Treatment Up-Regulates α3 and α7 Acetylcholine Receptor Subtypes Expressed by the Human Neuroblastoma Cell Line SH-SY5Y

1997 • 184 citations

Stable expression and pharmacological properties of the human α7 nicotinic acetylcholine receptor

1995 • 166 citations

An autoradiographic analysis of cholinergic receptors in mouse brain after chronic nicotine treatment.

1991 • 152 citations

Regulation of Human α4β2 Neuronal Nicotinic Acetylcholine Receptors by Cholinergic Channel Ligands and Second Messenger Pathways

1997 • 131 citations

Regulation of α₇Nicotinic Acetylcholine Receptors in the Developing Rat Somatosensory Cortex by Thalamocortical Afferents

1996 • 123 citations

Mechanisms of up-regulation of neuronal nicotinic acetylcholine receptors in clonal cell lines and primary cultures of fetal rat brain.

1995 • 117 citations

Pharmacological properties of the homomeric α7 receptor

1992 • 117 citations

In vitro neuroprotective properties of the novel cholinergic channel activator (ChCA), ABT-418

1996 • 105 citations

α-Bungarotoxin binding sites in rat hippocampal and cortical cultures: initial characterisation, colocalisation with α7 subunits and up-regulation by chronic nicotine treatment

1995 • 103 citations

Activation of α₇ nicotinic acetylcholine receptor promotes survival of spinal cord motoneurons

1997 • 101 citations

Human α 7 nicotinic acetylcholine receptor responses to novel ligands

1995 • 87 citations

Sensitivity to nicotine and brain nicotinic receptors are altered by chronic nicotine and mecamylamine infusion.

1994 • 80 citations

ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties.

1997 • 77 citations

Activation of the recombinant human alpha 7 nicotinic acetylcholine receptor significantly raises intracellular free calcium.

1997 • 74 citations

Elevation of intracellular calcium levels in neurons by nicotinic acetylcholine receptors

1996 • 72 citations

Differential regulation of neuronal nicotinic ACh receptor subunit genes in cultured neonatal rat sympathetic neurons: specific induction of alpha 7 by membrane depolarization through a Ca2+/calmodulin- dependent kinase pathway

1995 • 69 citations

Modulation of alpha7 nicotinic receptor-mediated calcium influx by nicotinic agonists.

1997 • 59 citations

Phosphorylation of the predicted major intracellular domains of the rat and chick neuronal nicotinic acetylcholine receptor α7 Subunit by cAMP-dependent protein kinase

1996 • 41 citations

Cloning and sequence of the human α7 nicotinic acetylcholine receptor

1993 • 39 citations

Glial Regulation of α7‐Type Nicotinic Acetylcholine Receptor Expression in Cultured Rat Cortical Neurons

1997 • 12 citations

Regulation of alpha-bungarotoxin sites in chromaffin cells in culture by nicotinic receptor ligands, K+, and cAMP.

1988 • 12 citations