Binding of peptides naturally presented by HLA–B27 to the differentially disease–associated B*2704 and B*2706 subtypes, and to mutants mimicking their polymorphism

ANKYLOSING SPONDYLITIS AND HL-A 27

1973 • 1,801 citations

MHC ligands and peptide motifs: first listing

1995 • 1,674 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

Empty MHC class I molecules come out in the cold

1990 • 933 citations

Crystal Structures of Two Viral Peptides in Complex with Murine MHC Class I H-2K ^b

1992 • 864 citations

Identification of self peptides bound to purified HLA-B27

1991 • 844 citations

Host resistance directed selectively against H-2-deficient lymphoma variants. Analysis of the mechanism.

1985 • 734 citations

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

1991 • 687 citations

The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC

1992 • 670 citations

Guilt by association: HLA-B27 and ankylosing spondylitis

1990 • 418 citations

HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis

1993 • 366 citations

Characterization of a monoclonal anti‐β₂‐microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens

1979 • 308 citations

The Origins of HLA‐A,B,C Polymorphism

1995 • 265 citations

HLA‐B27 subtypes in Asian patients with ankylosing spondylitis Evidence for new associations

1995 • 248 citations

Recognition of HLA-B27 and related antigen by a monoclonal antibody

1982 • 240 citations

HLA-B27 and its subtypes in world populations Editorial review

1995 • 231 citations

Relevance of residue 116 of HLA‐B27 in determining susceptibility to ankylosing spondylitis

1995 • 202 citations

Characteristics of endogenous peptides eluted from the class I MHC molecule HLA-B7 determined by mass spectrometry and computer modeling.

1993 • 164 citations

HLA class I typing by PCR: HLA-B27 and an African B27 subtype

1991 • 140 citations

Peptide binding to empty HLA-B27 molecules of viable human cells

1991 • 137 citations

Dominant aromatic/aliphatic C-terminal anchor in HLA-B*2702 and B*2705 peptide motifs

1994 • 129 citations

Distribution of HLA-B27 subtypes in patients with ankylosing spondylitis: the disease is associated with a common determinant of the various B27 molecules.

1987 • 107 citations

Structure and diversity of HLA-B27-specific T cell epitopes. Analysis with site-directed mutants mimicking HLA-B27 subtype polymorphism.

1990 • 73 citations

A novel HLA-B27 allele maps B27 allospecificity to the region around position 70 in the alpha 1 domain.

1991 • 70 citations

Current perspectives in reactive arthritis

1993 • 66 citations

Molecular analysis of a functional subtype of HLA-B27. A possible evolutionary pathway for HLA-B27 polymorphism.

1986 • 61 citations

Delineation of functional sites in HLA-B27 antigens. Molecular analysis of HLA-B27 variant Wewak I defined by cytolytic T lymphocytes.

1985 • 55 citations

Unusual topology of an HLA-B27 allospecific T cell epitope lacking peptide specificity.

1994 • 46 citations

Clonal analysis of alloreactive T cell responses against the closely related B*2705 and B*2703 subtypes. Implications for HLA-B27 association to spondyloarthropathy.

1994 • 46 citations

Changes in the repertoire of peptides bound to HLA-B27 subtypes and to site-specific mutants inside and outside pocket B.

1993 • 41 citations

Pocket Mutations of HLA-B27 Show That Anchor Residues Act Cumulatively to Stabilize Peptide Binding

1994 • 39 citations

The peptide binding specificity of HLA-B27 subtypes

1994 • 37 citations

Modulation of peptide binding by HLA‐B27 polymorphism in pockets A and B, and peptide specificity of B*2703

1995 • 33 citations

The nucleotide sequence of HLA-B * 2704 reveals a new amino acid substitution in exon 4 which is also present in HLA-B * 2706

1996 • 22 citations

Peptide-presenting similarities among functionally distant HLA-B27 subtypes revealed by alloreactive T lymphocytes of unusual specificity.

1992 • 19 citations

Structure, function, and disease association of HLA-B27

1994 • 19 citations

Structural polymorphism and function of HLA-B27

1995 • 17 citations

Structure of HLA‐B27‐specific T cell epitopes. Antigen presentation in B2703 is limited mostly to a subset of the antigenic determinants on B2705

1994 • 15 citations

The Asp116-His116 substitution in a novel HLA-B27 subtype influences the acceptance of the peptide C-terminal anchor

1995 • 13 citations

Nucleotide sequence of HLA-B * 2706

1994 • 13 citations

Differences in peptide-binding specificity of two ankylosing spondylitis-associated HLA-B27 subtypes

1995 • 13 citations

Nucleotide sequence of HLA-B * 2706

1995 • 13 citations