Modulation of peptide binding by HLA‐B27 polymorphism in pockets A and B, and peptide specificity of B*2703

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

1991 • 2,447 citations

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 Å resolution

1991 • 1,079 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

Empty MHC class I molecules come out in the cold

1990 • 933 citations

Crystal Structures of Two Viral Peptides in Complex with Murine MHC Class I H-2K ^b

1992 • 864 citations

Identification of self peptides bound to purified HLA-B27

1991 • 844 citations

The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.

1994 • 838 citations

Peptides Naturally Presented by MHC Class I Molecules

1993 • 803 citations

Host resistance directed selectively against H-2-deficient lymphoma variants. Analysis of the mechanism.

1985 • 734 citations

Emerging Principles for the Recognition of Peptide Antigens by MHC Class I Molecules

1992 • 730 citations

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

1990 • 717 citations

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

1991 • 687 citations

The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC

1992 • 670 citations

Specificity pockets for the side chains of peptide antigens in HLA-Aw68

1989 • 664 citations

Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules

1993 • 630 citations

HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides

1988 • 447 citations

Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing

1990 • 438 citations

MHC class II region encoding proteins related to the muKidrug resistance family of transmembrane transporters

1990 • 426 citations

Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle

1992 • 414 citations

HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis

1993 • 366 citations

Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter

1991 • 329 citations

Characterization of a monoclonal anti‐β₂‐microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens

1979 • 308 citations

Ham-2 corrects the class I antigen-processing defect in RMA-S cells

1992 • 289 citations

Atomic structure of a human MHC molecule presenting an influenza virus peptide

1992 • 254 citations

Recognition of HLA-B27 and related antigen by a monoclonal antibody

1982 • 240 citations

Two putative subunits of a peptide pump encoded in the human major histocompatibility complex class II region.

1991 • 173 citations

Peptide binding to empty HLA-B27 molecules of viable human cells

1991 • 137 citations

Dominant aromatic/aliphatic C-terminal anchor in HLA-B*2702 and B*2705 peptide motifs

1994 • 129 citations

HLA-B27 and HLA-A2 subtypes: structure, evolution and function

1989 • 119 citations

Intracellular transport of class I MHC molecules in antigen processing mutant cell lines.

1993 • 116 citations

Different HLA-B27 subtypes present the same immunodominant Epstein-Barr virus peptide.

1993 • 107 citations

Structural homologies between two HLA B27-restricted peptides suggest residues important for interaction with HLA B27

1990 • 105 citations

Structure and diversity of HLA-B27-specific T cell epitopes. Analysis with site-directed mutants mimicking HLA-B27 subtype polymorphism.

1990 • 73 citations

Differences in peptide presentation between B27 subtypes: The importance of the P1 side chain in maintaining high affinity peptide binding to B★2703

1994 • 65 citations

The HLA‐B73 antigen has a most unusual structure that defines a second lineage of HLA‐B alleles

1994 • 51 citations

Unusual topology of an HLA-B27 allospecific T cell epitope lacking peptide specificity.

1994 • 46 citations

Clonal analysis of alloreactive T cell responses against the closely related B*2705 and B*2703 subtypes. Implications for HLA-B27 association to spondyloarthropathy.

1994 • 46 citations

Changes in the repertoire of peptides bound to HLA-B27 subtypes and to site-specific mutants inside and outside pocket B.

1993 • 41 citations

Pocket Mutations of HLA-B27 Show That Anchor Residues Act Cumulatively to Stabilize Peptide Binding

1994 • 39 citations

The peptide binding specificity of HLA-B27 subtypes

1994 • 37 citations

Polymorphisms in pockets of major histocompatibility complex class I molecules influence peptide preference.

1993 • 33 citations

HLA-B73: an atypical HLA-B molecule carrying a Bw6-epitope motif variant and a B pocket identical to HLA-B27

1994 • 30 citations

Role of binding pockets for amino-terminal peptide residues in HLA-B27 allorecognition.

1992 • 26 citations

Structure, function, and disease association of HLA-B27

1994 • 19 citations

Structure of HLA‐B27‐specific T cell epitopes. Antigen presentation in B2703 is limited mostly to a subset of the antigenic determinants on B2705

1994 • 15 citations

Testing the importance of each residue in a HLA-B27-binding peptide using monoclonal antibodies.

1994 • 15 citations