Expression of mRNAs of multiple growth factors and receptors by neuronal cell lines: Detection with RT-PCR

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

Molecular cloning and expression of an IL-6 signal transducer, gp130

1990 • 1,307 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

Gene transfer and molecular cloning of the rat nerve growth factor receptor

1987 • 946 citations

cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily

1988 • 896 citations

Insulin-like growth factor II receptor as a multifunctional binding protein

1987 • 858 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

Primary structure and functional expression of rat and human stem cell factor DNAs

1990 • 779 citations

The neurotrophic factor concept: a reexamination

1993 • 745 citations

Expression cloning and characterization of the TGF-β type III receptor

1991 • 638 citations

The Receptor for Ciliary Neurotrophic Factor

1991 • 604 citations

trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

1989 • 604 citations

Human basic fibroblast growth factor: nucleotide sequence and genomic organization.

1986 • 604 citations

Molecular and biochemical characterization of the human trk proto-oncogene.

1989 • 600 citations

Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130.

1991 • 587 citations

Embryonic expression of a haematopoietic growth factor encoded by the SI locus and the ligand for c-kit

1990 • 521 citations

Steel locus defines new multipotent growth factor

1990 • 509 citations

cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor.

1989 • 413 citations

Embryonic RNA expression patterns of the c-kit receptor and its cognate ligand suggest multiple functional roles in mouse development.

1991 • 346 citations

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules.

1988 • 338 citations

Molecular Cloning and Expression of Rat Interleukin-1α cDNA

1989 • 332 citations

Human epidermal growth factor precursor: cDNA sequence, expressionin vitroand gene organization

1986 • 321 citations

The effect of fibroblast growth factor on PC12 cells

1985 • 270 citations

Cytokine receptors and signal transduction

1992 • 269 citations

Isolation and characterization of a cloned rat insulin gene

1979 • 229 citations

Localization of mRNA for c-kit receptor and its ligand in the brain of adult rats: an analysis using in situ hybridization histochemistry

1992 • 226 citations

Expression of c-kit receptor in normal and transformed human nonlymphoid tissues.

1992 • 208 citations

A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF

1990 • 205 citations

The emerging neuropoietic cytokine family: first CDF/LIF, CNTF and IL-6; next ONC, MGF, GCSF?

1992 • 135 citations

Molecular and Biochemical Characterization of the Human trk Proto-Oncogene

1989 • 124 citations

The Rat Insulin Receptor: Primary Structure and Conservation of Tissue-Specific Alternative Messenger RNA Splicing

1990 • 119 citations

Detection of cytokine mRNA in astrocyte cultures using the polymerase chain reaction.

1990 • 112 citations

Recombinant Human and Rat Ciliary Neurotrophic Factors

1991 • 96 citations

CNTF, FGF, and NGF collaborate to drive the terminal differentiation of MAH cells into postmitotic neurons

1994 • 92 citations

Primary Structure and Biological Activity of Human Brain-Derived Neurotrophic Factor

1991 • 87 citations

Localization of cholinergic differentiation factor/leukemia inhibitory factor mRNA in the rat brain and peripheral tissues.

1991 • 83 citations

c-kit receptor and ligand expression in postnatal development of the mouse cerebellum suggests a function for c-kit in inhibitory interneurons

1992 • 81 citations

cDNA Cloning and Expression of a Human Platelet-Derived Growth Factor (PDGF) Receptor Specific for B-Chain-Containing PDGF Molecules

1988 • 76 citations

Evolutionary Origins of the Transforming Growth Factor-β Gene Family

1992 • 71 citations

Expression of Glia Maturation Factor β mRNA and Protein in Rat Organs and Cells

1993 • 69 citations

Basic fibroblast growth factor (bFGF), a multifunctional growth factor for neuroectodermal cells

1990 • 67 citations

The Induction of Ornithine Decarboxylase by Nerve Growth Factor and Epidermal Growth Factor in PC 12 Cells

1981 • 54 citations

Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells

1991 • 50 citations

Expression of mRNAs of multiple growth factors and receptors by astrocytes and glioma cells: Detection with reverse transcription-polymerase chain reaction

1995 • 49 citations

cDNA Cloning and Expression of a Human FGF Receptor which Binds Acidic and Basic FGF

1991 • 38 citations

Basic Fibroblast Growth Factor in Neurons and Its Putative Functions^a

1991 • 32 citations

Ciliary neurotrophic factor (CNTF) enhances the effects of nerve growth factor on PC12 cells

1994 • 23 citations

[23] Human insulin-like growth factor I and II messenger RNA: Isolation of complementary DNA and analysis of expression

1987 • 23 citations

Detection of β-nerve growth factor mRNA in the human fetal brain

1990 • 10 citations

Insulin-like growth factor I receptor cDNA cloning

1991 • 7 citations