Studies of the phosphorylation of Escherichia coli isocitrate dehydrogenase. Recognition of the enzyme by isocitrate dehydrogenase kinase/phosphatase and effects of phosphorylation on its structure and properties

Silver staining of proteins in polyacrylamide gels

1981 • 3,565 citations

Inactivation of isocitrate dehydrogenase by phosphorylation is mediated by the negative charge of the phosphate.

1987 • 300 citations

The Synthesis of Ribonuclease A

1971 • 293 citations

Phosphorylation of Isocitrate Dehydrogenase of Escherichia coli

1979 • 238 citations

A protein with kinase and phosphatase activities involved in regulation of tricarboxylic acid cycle

1982 • 212 citations

Phosphorylation of isocitrate dehydrogenase as a demonstration of enhanced sensitivity in covalent regulation

1983 • 192 citations

Protein Phosphorylation in Prokaryotes

1988 • 188 citations

Determination of flux through the branch point of two metabolic cycles. The tricarboxylic acid cycle and the glyoxylate shunt.

1984 • 174 citations

Reversible Inactivation of the Isocitrate Dehydrogenase of Escherichia coli ML308 during Growth on Acetate

1975 • 89 citations

The phosphorylation of Escherichia coli isocitrate dehydrogenase in intact cells

1984 • 67 citations

Control of Enzyme Activity

1983 • 58 citations

Partial purification and properties of isocitrate dehydrogenase kinase/phosphatase from Escherichia coli ML308

1984 • 53 citations

Nucleotide sequence of aceK, the gene encoding isocitrate dehydrogenase kinase/phosphatase

1988 • 50 citations

Isolation of active and inactive forms of isocitrate dehydrogenase from Escherichia coli ML308

1984 • 47 citations

Control of Escherichia coli isocitrate dehydrogenase: an example of protein phosphorylation in a prokaryote

1984 • 44 citations

Nucleotide sequence and expression of the aceK gene coding for isocitrate dehydrogenase kinase/phosphatase in Escherichia coli

1988 • 44 citations

Amino acid sequence round the site of phosphorylation in isocitrate dehydrogenase from Escherichia coli ML308

1984 • 33 citations

A comparison of the phosphorylated and unphosphorylated forms of isocitrate dehydrogenase from Escherichia coli ML308

1984 • 24 citations

Applications of recombinant DNA technology to studies of metabolic regulation

1987 • 22 citations

Regulation of bacterial metabolism by protein phosphorylation.

1987 • 14 citations

Amino acid sequence of the phosphorylation site of isocitrate dehydrogenase fromEscherichia coli

1984 • 14 citations

Evidence for an arginine residue at the coenzyme-binding site of Escherichia coli isocitrate dehydrogenase

1989 • 10 citations

Structure and regulation of Escherichia coli isocitrate dehydrogenase

1989 • 2 citations