The effect of sodium thiosulfate on ototoxicity and pharmacokinetics after cisplatin treatment in guinea pigs

Cisplatin

1984 • 942 citations

Intraperitoneal Cisplatin with Systemic Thiosulfate Protection

1982 • 494 citations

High-Dose Cisplatin in Hypertonic Saline

1984 • 335 citations

Long-term survival in ovarian cancer

1991 • 210 citations

Rapid superselective high‐dose cisplatin infusion for advanced head and neck malignancies

1992 • 198 citations

Intraperitoneal cis-diamminedichloroplatinum with systemic thiosulfate protection.

1983 • 194 citations

Cisplatin‐Induced Ototoxicity: The Effect of Pigmentation and Inhibitory Agents

1993 • 154 citations

Ototoxicity of cis-diamminedichloroplatinum (II): Influence of dose, schedule and mode of administration

1983 • 139 citations

Pharmacokinetics of free and total platinum species after rapid and prolonged infusions of cisplatin

1986 • 130 citations

The ototoxic mechanism of cisplatin

1990 • 129 citations

Effect of Sodium Thiosulfate on the Pharmacokinetics and Toxicity of Cisplatin

1989 • 99 citations

The ototoxic effect of cisplatin on guinea pigs in relation to dosage

1989 • 92 citations

The comparative effects of sodium thiosulfate, diethyldithiocarbamate, fosfomycin and WR-2721 on ameliorating cisplatin-induced ototoxicity

1995 • 84 citations

Effects of cisplatin and thiosulfate upon auditory brainstem responses of guinea pigs

1988 • 82 citations

Cisplatin and its analogues in the treatment of advanced breast cancer: a review

1992 • 76 citations

Cisplatin rescue therapy: Experience with sodium thiosulfate, WR2721, and diethyldithiocarbamate

1990 • 66 citations

A possible cellular mechanism of cisplatin-induced nephrotoxicity

1989 • 66 citations

Comparative Ototoxicity of Cisplatin during Acute and Chronic Treatment

1994 • 62 citations

Cisplatinum: A review, with special reference to cellular and molecular interactions

1984 • 54 citations

Nephrotoxicity of cisplatin, carboplatin and transplatin

1990 • 50 citations

Protection by sodium thiosulfate and thiourea against lethal toxicity of cis-diamminedichloroplatinum(II) in bacteria and mice.

1981 • 47 citations

"Two-route chemotherapy" using high-dose ip cisplatin and iv sodium thiosulfate, its antidote, for peritoneally disseminated cancer in mice.

1984 • 42 citations

Sodium thiosulfate inhibits cis-diamminedichloroplatinum (II) activity

1984 • 40 citations

Effectiveness of "two-route chemotherapy" using cisplatin and its antidote, sodium thiosulfate, on lifespan of rats bearing metastatic liver tumors.

1983 • 35 citations

Inactivation of cis-diamminedichloroplatinum (II) in blood and protection of its toxicity by sodium thiosulfate in rabbits

1985 • 34 citations

Efficacy of "two-route chemotherapy" using intra-arterial cisplatin and iv sodium thiosulfate, its antidote, in rat bladder tumor.

1983 • 29 citations

‘Two-route chemotherapy’ using intra-arterial cisplatin and intravenous sodium thiosulfate, its neutralizing agent, for hepatic malignancies

1988 • 28 citations

Semiquantitative analysis by scanning electron microscopy of cochlear hair cell damage by ototoxic drugs.

1995 • 26 citations

‘Two-Route Chemotherapy’ Using Cisplatin and Its Neutralizing Agent, Sodium Thiosulfate, for Intraperitoneal Cancer

1990 • 25 citations

Protection of antiproliferative effect of cis-diamminedichloroplatinum (II) by sodium thiosulfate

1986 • 24 citations

Neutralizing effect of sodium thiosulfate on antitumor efficacy of cisplatin for human carcinoma xenografts in nude mice

1991 • 20 citations

Phase II trial for intraperitoneal cisplatin plus intravenous sodium thiosulphate in advanced ovarian carcinoma patients with minimal residual disease after cisplatin-based chemotherapy—a phase II study of the EORTC gynaecological cancer cooperative group

1994 • 20 citations

X-Ray Microanalysis and Ion Microscopy of Guinea Pig Cochlea and Kidney after Cisplatin Treatment

1994 • 11 citations

Ototoxicity of the New Platinum AnticancerAgent TRK-710 in Comparison with Cisplatin

1995 • 10 citations