Insulin-like Growth Factor Receptor-1 Stimulates Phosphorylation of the β2-Adrenergic Receptor in Vivo on Sites Distinct from Those Phosphorylated in Response to Insulin

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

SH2 domains recognize specific phosphopeptide sequences

1993 • 2,685 citations

Turning off the signal: desensitization of β‐adrenergic receptor function

1990 • 1,241 citations

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

1994 • 886 citations

Use of an oriented peptide library to determine the optimal substrates of protein kinases

1994 • 645 citations

Peptides and Protein Phosphorylation

2018 • 525 citations

An Approach to Locate Phosphorylation Sites in a Phosphoprotein: Mass Mapping by Combining Specific Enzymatic Degradation with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

1994 • 142 citations

Cross-regulation between G-protein-mediated pathways. Stimulation of adenylyl cyclase increases expression of the inhibitory G-protein, Gi alpha 2.

1990 • 140 citations

A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells.

1991 • 138 citations

Mediation of growth factor induced DNA synthesis and calcium mobilization by Gq and Gi2.

1993 • 106 citations

Cross-talk between tyrosine kinase and G-protein-linked receptors. Phosphorylation of beta 2-adrenergic receptors in response to insulin.

1992 • 102 citations

Analysis of the fibroblast transformation potential of GTPase-deficient gip2 oncogenes.

1992 • 101 citations

The β-Adrenergic Receptor Is a Substrate for the Insulin Receptor Tyrosine Kinase

1996 • 98 citations

Effect of Thyroid Status on Insulin Action in Rat Adipocytes and Skeletal Muscle

1980 • 78 citations

Mapping and sequence‐specific identification of phosphopeptides in unfractionated protein digest mixtures by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry

1992 • 78 citations

A rapid method for the measurement of [γ-32P]ATP specific radioactivity in tissue extracts and its application to the study of 32Pi uptake in perfused rat heart

1976 • 75 citations

Growth factor‐induced cell division is paralleled by translocation of G _iα to the nucleus

1991 • 75 citations

Phosphorylation of Tyrosyl Residues 350/354 of the β-Adrenergic Receptor Is Obligatory for Counterregulatory Effects of Insulin

1995 • 72 citations

Catalysis of serine and tyrosine autophosphorylation by the human insulin receptor.

1992 • 69 citations

Regulating expression and function of G-protein-linked receptors

1996 • 41 citations

Transformation of Rat-1 fibroblasts with the v-src oncogene increases the tyrosine phosphorylation state and activity of the alpha subunit of Gq/G11.

1996 • 33 citations

Cross-regulation between G-protein-mediated pathways. Acute activation of the inhibitory pathway of adenylylcyclase reduces beta 2-adrenergic receptor phosphorylation and increases beta-adrenergic responsiveness.

1992 • 28 citations