Matrix metalloproteinase-3 removes agrin from synaptic basal lamina

Matrix Metalloproteinases

1999 • 3,774 citations

Defective Neuromuscular Synaptogenesis in Agrin-Deficient Mutant Mice

1996 • 915 citations

The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

1996 • 881 citations

Acetylcholine receptors in regenerating muscle accumulate at original synaptic sites in the absence of the nerve.

1979 • 355 citations

Agrin Is a Heparan Sulfate Proteoglycan

1995 • 281 citations

Matrix metalloproteinases

1997 • 247 citations

Basement Membrane and Repair of Injury to Peripheral Nerve: Defining a Potential Role for Macrophages, Matrix Metalloproteinases, and Tissue Inhibitor of Metalloproteinases-1

1996 • 242 citations

Alternatively Spliced Isoforms of Nerve- and Muscle-Derived Agrin

1999 • 236 citations

Matrix metalloproteinases

1997 • 231 citations

Agrin-like molecules at synaptic sites in normal, denervated, and damaged skeletal muscles.

1987 • 177 citations

Matrix metalloproteinase inhibitors

1998 • 110 citations

Effect of low calcium and protease inhibitors on synapse elimination during postnatal development in the rat soleus muscle

1986 • 108 citations

Electron microscopic structure of agrin and mapping of its binding site in laminin-1

1998 • 104 citations

A Molecular Mechanism for Synapse Elimination: Novel Inhibition of Locally Generated Thrombin Delays Synapse Loss in Neonatal Mouse Muscle

1996 • 100 citations

Cell type-specific regulation of SL-1 and SL-2 genes. Induction of the SL-2 gene but not the SL-1 gene by human keratinocytes in response to cytokines and phorbolesters

1993 • 97 citations

A gene for a severe lethal form of X-linked arthrogryposis (X-linked infantile spinal muscular atrophy) maps to human chromosome Xp11.3-q11.2

1995 • 87 citations

Proteolytic activity, synapse elimination, and the Hebb synapse

1994 • 83 citations

Axon Withdrawal during Synapse Elimination at the Neuromuscular Junction Is Accompanied by Disassembly of the Postsynaptic Specialization and Withdrawal of Schwann Cell Processes

1998 • 74 citations

Schwann cell proliferation and localized proteolysis: expression of plasminogen-activator activity predominates in the proliferating cell populations.

1984 • 64 citations

Stromelysin generates a fibronectin fragment that inhibits Schwann cell proliferation.

1992 • 63 citations

Differences in proliferation and invasion by normal, transformed and NF1 Schwann cell cultures are influenced by matrix metalloproteinase expression

1995 • 63 citations

Decrease in plasminogen activator correlates with synapse elimination during neonatal development of mouse skeletal muscle.

1989 • 58 citations

Isoforms of agrin are widely expressed in the developing rat and may function as protease inhibitors

1993 • 46 citations

Secreted Proteases

1990 • 42 citations

Arthrogryposis multiplex congenita due to congenital myasthenic syndrome

1995 • 36 citations

Differential distribution of five members of the matrix metalloproteinase family and one inhibitor (TIMP-1) in human liver and skin

1997 • 27 citations

Chromosomal assignment of the gene encoding the human tissue inhibitor of metalloproteinases to Xp11.1–p11.4

1987 • 27 citations

Plasminogen activators and their inhibitors in the neuromuscular system: I. Developmental regulation of plasminogen activator isoforms during in vitro myogenesis in two cell lines

1990 • 18 citations

Anti-agrin staining is absent at abandoned synaptic sites of frog neuromuscular junctions

1996 • 18 citations

Agrin and acetylcholine receptors are removed from abandoned synaptic sites at reinnervated frog neuromuscular junctions

1997 • 14 citations

Aggregates of acetylcholine receptors are not observed under anti-agrin staining Schwann cell processes at the frog neuromuscular junction

1999 • 8 citations

Agrin and acetylcholine receptors are removed from abandoned synaptic sites at reinnervated frog neuromuscular junctions

1997 • 8 citations