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1996 • 656 citations

Increase of extracellular dopamine in the prefrontal cortex: a trait of drugs with antidepressant potential?

1994 • 317 citations

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1995 • 312 citations

Noradrenergic modulation of midbrain dopamine cell firing elicited by stimulation of the locus coeruleus in the rat

1993 • 292 citations

Serotonin (5-HT)2C receptors tonically inhibit dopamine (DA) and noradrenaline (NA), but not 5-HT, release in the frontal cortex in vivo

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1990 • 261 citations

Early desensitization of somato-dendritic 5-HT1A autoreceptors in rats treated with fluoxetine or paroxetine

1995 • 257 citations

Clonazepam and imipramine in the treatment of panic attacks: a double-blind comparison of efficacy and side effects.

1990 • 220 citations

Serotonin-dopamine interaction in the rat ventral tegmental area: an electrophysiological study in vivo.

1994 • 210 citations

Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release

1998 • 202 citations

Cellular localization of messenger RNA for beta-1 and beta-2 adrenergic receptors in rat brain: An in situ hybridization study

1993 • 202 citations

5-HT Receptors: Subtypes and Second Messengers

1991 • 200 citations

Neuropsychological and neuroimaging evidence for the involvement of the frontal lobes in depression

1997 • 200 citations

Effect of Pindolol on the Function of Pre- and Postsynaptic 5-HT1A Receptors: In Vivo Microdialysis and Electrophysiological Studies in the Rat Brain

1996 • 179 citations

Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: a double-blind, placebo-controlled trial

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1992 • 167 citations

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1997 • 136 citations

Potentiation of the Fluoxetine‐Induced Increase in Dialysate Levels of Serotonin (5‐HT) in the Frontal Cortex of Freely Moving Rats by Combined Blockade of 5‐HT_1A and 5‐HT_1B Receptors with WAY 100,635 and GR 127,935

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1990 • 125 citations

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Biochemical evidence for the regulation of central noradrenergic activity by 5-HT1A and 5-HT2 receptors: Microdialysis studies in the awake and anaesthetized rat

1994 • 124 citations

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Application of brain microdialysis to study the pharmacology of the 5-HT1A autoreceptor

1990 • 110 citations

Effect of 5-HT1A Receptor Antagonists on Citalopram-induced Increase in Extracellular Serotonin in the Frontal Cortex, Striatum and Dorsal Hippocampus

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Functional properties of the rat and human beta 3-adrenergic receptors: differential agonist activation of recombinant receptors in Chinese hamster ovary cells.

1992 • 100 citations

Induction of burst firing in ventral tegmental area dopaminergic neurons by activation of serotonin (5-HT)1A receptors: WAY 100,635-reversible actions of the highly selective ligands, flesinoxan and S 15535

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Pindolol: A New β-Adrenoceptor Antagonist with Partial Agonist Activity

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Cocaine- and amphetamine-regulated transcript (CART) peptide immunoreactivity in myenteric plexus neurons of the rat ileum and co-localization with choline acetyltransferase

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Interactions of (+)- and (-)-8- and 7-hydroxy-2-(di-n-propylamino)tetralin at human (h)D3, hD2 and h serotonin1A receptors and their modulation of the activity of serotoninergic and dopaminergic neurones in rats.

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Systemic uptake inhibition decreases serotonin release via somatodendritic autoreceptor activation

1995 • 94 citations

The 5-HT1A receptor antagonist (S)-UH-301 augments the increase in extracellular concentrations of 5-HT in the frontal cortex produced by both acute and chronic treatment with citalopram

1996 • 93 citations

In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol.

1993 • 85 citations

Shuttle-box deficits induced by inescapable shocks in rats: Reversal by the beta-adrenoreceptor stimulants clenbuterol and salbutamol

1986 • 85 citations

Pindolol augmentation of antidepressant therapy

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The Selective 5-HT_1BReceptor Inverse Agonist 1‘-Methyl-5-[[2‘-methyl-4‘- (5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4‘-piperidine] (SB-224289) Potently Blocks Terminal 5-HT Autoreceptor Function Both in Vitro and in Vivo

1998 • 80 citations

Antagonist properties of (−)‐pindolol and WAY 100635 at somatodendritic and postsynaptic 5‐HT_1A receptors in the rat brain

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(−)-Pindolol, but not buspirone, potentiates the citalopram-induced rise in extracellular 5-hydroxytryptamine

1996 • 77 citations

Lack of 5-HT1A autoreceptor desensitization following chronic citalopram treatment, as determined by in vivo microdialysis

1994 • 75 citations

Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5‐HT_1A autoreceptor in vivo

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Simultaneous Increases of Extracellular Monoamines in Microdialysates from Hypothalamus of Conscious Rats by Duloxetine, a Dual Serotonin and Norepinephrine Uptake Inhibitor

1995 • 73 citations

Augmentation strategies in patients with refractory depression

1996 • 70 citations

Buspirone Enhances Duloxetine‐ and Fluoxetine‐Induced Increases in Dialysate Levels of Dopamine and Noradrenaline, but Not Serotonin, in the Frontal Cortex of Freely Moving Rats

1997 • 68 citations

Agonist and Antagonist Actions of (-)Pindolol at Recombinant, Human Serotonin1A (5-HT1A) Receptors

1998 • 67 citations

Local 5HT3 receptors mediate fluoxetine but not desipramine-induced increase of extracellular dopamine in the prefrontal cortex

1995 • 66 citations

Effects of 5-HT1A receptor antagonists on fluoxetine-induced changes in extracellular serotonin concentrations in rat frontal cortex

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Raphe 5-HT1A autoreceptors, but not postsynaptic 5-HT1A receptors or β-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo

1996 • 62 citations

Regulation of β₁‐Adrenergic Receptor mRNA and Ligand Binding by Antidepressant Treatments and Norepinephrine Depletion in Rat Frontal Cortex

1993 • 59 citations

Regional differences in the effect of the combined treatment of WAY 100635 and fluoxetine: an in vivo microdialysis study

1996 • 59 citations

cAMP-dependent Facilitation of Glutamate Release by β-Adrenergic Receptors in Cerebrocortical Nerve Terminals

1996 • 59 citations

Chronic administration of the 5-HT1A receptor agonist 8-OH-DPAT differentially desensitizes 5-HT1A autoreceptors of the dorsal and median raphe nuclei

1997 • 58 citations

The effect of paroxetine on 5-HT efflux in the rat dorsal raphe nucleus is potentiated by both 5-HT1A and receptor antagonists

1995 • 57 citations

Potentiation of the time-dependent, antidepressant-induced changes in the agonistic behaviour of resident rats by the 5-HT1A receptor antagonist, WAY-100635

1997 • 55 citations

Excitatory amino acid action on the release of brain neurotransmitters and neuromodulators: Biochemical studies

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Antidepressant profile in rodents of SR 58611A, a new selective agonist for atypical β-adrenoceptors

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Interaction of beta adrenergic agonists and antagonists with brain beta adrenergic receptors in vivo.

1987 • 50 citations

Child and adolescent mood disorders—experience with serotonin-based therapies

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Characteristics of 125I-iodocyanopindolol binding to .BETA.-adrenergic and serotonin-1B receptors of rat brain: Selectivity of .BETA.-adrenergic agents.

1990 • 45 citations

S 15535, a novel benzodioxopiperazine ligand of serotonin (5-HT)1A receptors: I. Interaction with cloned human (h)5-HT1A, dopamine hD2/hD3 and h alpha2A-adrenergic receptors in relation to modulation of cortical monoamine release and activity in models of potential antidepressant activity.

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Pindolol does not act only on 5-HT 1A receptors in augmenting antidepressant activity in the mouse forced swimming test

1998 • 37 citations

WAY 100,635 enhances both the `antidepressant' actions of duloxetine and its influence on dialysate levels of serotonin in frontal cortex

1998 • 37 citations

Involvement of beta-1 and beta-2 adrenergic receptors in the antidepressant-like effects of centrally administered isoproterenol.

1994 • 36 citations

Synergistic neurochemical and behavioral effects of fluoxetine and 5-HT1A receptor antagonists

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(−)-Pindolol and (±)-Tertatolol Affect Rat Hippocampal 5-HT Levels Through Mechanisms Involving Not Only 5-HT1A, But Also 5-HT1B Receptors

1996 • 35 citations

Effect of pindolol on hormone secretion and body temperature: Partial agonist effects

1996 • 34 citations

Contrasting effects of chronic paroxetine on 5-HT1A control of dorsal raphe cell firing and 5-HT release

1998 • 27 citations

Facilitation of noradrenaline release from rat brain slices by \-adrenoceptors

1995 • 25 citations

Serotonergic synergism: the risks and benefits of combining the selective serotonin reuptake inhibitors with other serotonergic drugs

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Pharmacology of β-Blockers

1990 • 22 citations

Pharmacological Characterization of the Discriminative Stimulus Effects of Clenbuterol in Rats

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Differentiation of 5-HT1A receptor ligands by drug discrimination

1997 • 17 citations

Neuroanatomical specificity and dose dependence in the time course of imipramine-induced beta adrenergic receptor down-regulation in rat brain.

1994 • 15 citations

Synergism of 5-HT 1B/D Antagonists With Paroxetine on Serotonin Efflux in Rat Ventral Lateral Geniculate Nucleus Slices

1997 • 12 citations

Flerobuterol, aβ-adrenoceptor agonist, enhances serotonergic neurotransmission: an electrophysiological study in the rat brain

1991 • 11 citations

Is the β-down-regulation a prerequisite of the antidepressant activity?

1994 • 10 citations

Chronic administration of the 5‐HT1A receptor agonist 8‐OH‐DPAT differentially desensitizes 5‐HT1A autoreceptors of the dorsal and median raphe nuclei

1997 • 7 citations

Augmentation of selective serotonin reuptake inhibitor antidepressant efficacy with pindolol and the relevance of 5HT1A autoreceptors

1996 • 5 citations

Pindolol Augmentation of Antidepressant Therapy

1999 • 3 citations

Augmentation of selective serotonin reuptake inhibitor antidepressant efficacy with pindolol and the relevance of 5HT1A autoreceptors

1996 • 1 citations