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Establishment of an Osteocyte-like Cell Line, MLO-Y4

Data up to Jan 2025

Published1997
Citations518
References40

Total Citations Per Year

Abstract

References (40)

Increased bone formation in osteocalcin-deficient mice

1996 • 1,692 citations

OSTEOBLASTIC CELLS ARE INVOLVED IN OSTEOCLAST FORMATION

1988 • 943 citations

Sensitivity of osteocytes to biomechanical stress in vitro

1995 • 768 citations

Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I

1993 • 625 citations

Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene.

1988 • 523 citations

Establishment of a clonal osteogenic cell line from newborn mouse calvaria

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Cell Lines of the Pituitary Gonadotrope Lineage Derived by Targeted Oncogenesis in Transgenic Mice

1990 • 493 citations

Function of osteocytes in bone

1994 • 402 citations

Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo

1989 • 357 citations

Morphological study of intercellular junctions during osteocyte differentiation

1990 • 254 citations

Connexin43 and connexin45 form gap junctions with different molecular permeabilities in osteoblastic cells.

1994 • 240 citations

Connexin43 mediates direct intercellular communication in human osteoblastic cell networks.

1993 • 227 citations

Increased insulin-like growth factor I mRNA expression in rat osteocytes in response to mechanical stimulation

1995 • 191 citations

Cell and molecular biology of vertebrate hard tissues.

1988 • 156 citations

Localization of 1,25-(OH)2D3-responsive alkaline phosphatase in osteoblast-like cells (ROS 17/2.8, MG 63, and MC 3T3) and growth cartilage cells in culture

1989 • 150 citations

Osteocyte Differentiation in the Tibia of Newborn Rabbit: An Ultrastructural Study of the Formation of Cytoplasmic Processes

1990 • 147 citations

Matrix mineralization and the differentiation of osteocyte-like cells in culture

1995 • 141 citations

The Cellular Basis of Bone Turnover and Bone Loss

1977 • 135 citations

Isolation and purification of osteocytes

1992 • 133 citations

Increased3H-uridine levels in osteocytes following a single short period of dynamic bone loadingin vivo

1988 • 131 citations

Distinct responses of different populations of bone cells to mechanical stress.

1996 • 127 citations

CD44 expression in human bone: A novel marker of osteocytic differentiation

1994 • 125 citations

Hormonal regulation of intercellular communication: parathyroid hormone increases connexin 43 gene expression and gap-junctional communication in osteoblastic cells.

1992 • 124 citations

Latent Forms of Transforming Growth Factor-β (TGFβ) Derived from Bone Cultures: Identification of a Naturally Occurring 100-kDa Complex with Similarity to Recombinant Latent TGFβ

1991 • 119 citations

Characterization of gap junctions between osteoblast-like cells in culture

1992 • 112 citations

Localization of the expression of types I, III, and IV collagen, TGF-β1 and c-fos genes in developing human calvarial bones

1988 • 109 citations

Identification of osteocytes in osteoblast-like cell cultures using a monoclonal antibody specifically directed against osteocytes

1986 • 100 citations

Localization of the mRNA for bone matrix proteins during fracture healing as determined by in situ hybridization

1994 • 93 citations

Localization of CD44, the hyaluronate receptor; on the plasma membrane of osteocytes and osteoclasts in rat tibiae

1995 • 85 citations

Exogenous prostacyclin, but not prostaglandin E2, produces similar responses in both G6PD activity and RNA production as mechanical loading, and increases IGF-II release, in adult cancellous bone in culture

1993 • 83 citations

Terminal differentiation of osteogenic cells in the embryonic chick tibia is revealed by a monoclonal antibody against osteocytes

1990 • 71 citations

Establishment and hormonal regulation of a conditionally transformed preosteocytic cell line from adult human bone.

1996 • 69 citations

Constitutive in vivo mRNA expression by osteocytes of β-actin, osteocalcin, connexin-43, IGF-I, c-fos and c-jun, but not TNF-α nor tartrate-resistant acid phosphatase

1996 • 63 citations

Hormonal regulation of intercellular communication: parathyroid hormone increases connexin 43 gene expression and gap-junctional communication in osteoblastic cells

1992 • 58 citations

Relationship between the Expression of the Gap Junction Protein and Osteoblast Phenotype in a Human Osteoblastic Cell Line during Cell Proliferation.

1993 • 52 citations

Age-related reduction in bone matrix protein mRNA expression in rat bone tissues: application of histomorphometry to in situ hybridization

1995 • 47 citations

CD44 Expression in Fetal Rat Bone:In Vivoandin VitroAnalysis

1996 • 46 citations

Hormonal Regulation of Connexin 43 Expression and Gap Junctional Communication in Human Osteoblastic Cells.

1994 • 45 citations

Osteoblastic cell lines derived from a transgenic mouse containing the osteocalcin promoter driving SV40 T-antigen

1995 • 36 citations

Localization of CD44, the hyaluronate receptor, on the plasma membrane of osteocytes and osteoclasts in rat tibiae

1995 • 27 citations

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Establishment of an Osteocyte-like Cell Line, MLO-Y4 (1997) – Journal of Bone and Mineral Research | Metascience Observatory Explorer