Exogenous prostacyclin, but not prostaglandin E2, produces similar responses in both G6PD activity and RNA production as mechanical loading, and increases IGF-II release, in adult cancellous bone in culture

Regulation of bone formation by applied dynamic loads.

1984 • 1,533 citations

Regulation of bone mass by mechanical strain magnitude

1985 • 1,285 citations

Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo

1989 • 357 citations

Parathyroid Hormone Enhances the Transcript and Polypeptide Levels of Insulin-Like Growth Factor I in Osteoblast-Enriched Cultures from Fetal Rat Bone*

1989 • 337 citations

Cortical hyperostosis following long-term administration of prostaglandin E1 in infants with cyanotic congenital heart disease

1980 • 277 citations

Prostaglandin E2 enhances cortical bone mass and activates intracortical bone remodeling in intact and ovariectomized female rats

1990 • 256 citations

Direct transformation from quiescence to bone formation in the adult periosteum following a single brief period of bone loading

1988 • 214 citations

Stimulation of bone formation by prostaglandin E2

1984 • 212 citations

Primary structure of human skeletal growth factor: homology with human insulin-like growth factor-II

1988 • 204 citations

Cellular responses to mechanical loading in vitro

1990 • 202 citations

Prostaglandin E₂Stimulates Insulin-Like Growth Factor I Synthesis in Osteoblast-Enriched Cultures from Fetal Rat Bone*

1991 • 197 citations

Loading-related increases in prostaglandin production in cores of adult canine cancellous bone in vitro: A role for prostacyclin in adaptive bone remodeling?

1991 • 191 citations

Tensile forces enhance prostaglandin E synthesis in osteoblastic cells grown on collagen ribbons

1984 • 184 citations

The proliferative and synthetic response of isolated calvarial bone cells of rats to cyclic biaxial mechanical strain.

1991 • 180 citations

The transduction of mechanical force into biochemical events in bone cells may involve activation of phospholipase A2

1988 • 161 citations

The proliferative and synthetic response of isolated calvarial bone cells of rats to cyclic biaxial mechanical strain.

1991 • 155 citations

Indomethacin modulation of load-related stimulation of new bone formationin vivo

1989 • 151 citations

The effect of strain on bone cell prostaglandin E2 release: A new experimental method

1990 • 151 citations

Estradiol Regulation of Insulin-Like Growth Factor-I Expression in Osteoblastic Cells: Evidence for Transcriptional Control

1991 • 138 citations

1,25-Dihydroxyvitamin D3 Differentially Regulates the Production of Insulin-Like Growth Factor I (IGF-I) and IGF-Binding Protein-4 in Mouse Osteoblasts*

1991 • 132 citations

Increased3H-uridine levels in osteocytes following a single short period of dynamic bone loadingin vivo

1988 • 131 citations

The role of bone cells in increasing metaphyseal hard tissue in rapidly growing rats treated with prostaglandin E2

1987 • 121 citations

Inhibition of osteoclastic motility by prostaglandins I₂, E₁, E₂ and 6‐oxo‐E₁

1983 • 107 citations

Practical histochemistry

1974 • 106 citations

Early loading-related changes in the activity of glucose 6-phosphate dehydrogenase and alkaline phosphatase in osteocytes and periosteal osteoblasts in rat fibulae in vivo

1993 • 106 citations

Prostaglandin E2 prevents bone loss and adds extra bone to immobilized distal femoral metaphysis in female rats

1992 • 103 citations

Stimulation of bone nodule formation in vitro by prostaglandins E1 and E2.

1992 • 102 citations

Development of Valid Methods to Measure Insulin-Like Growth Factors-I and -II in Bone Cell-Conditioned Medium*

1990 • 79 citations

Early strain-related changes in cultured embryonic chick tibiotarsi parallel those associated with adaptive modeling in vivo

1993 • 78 citations

Triiodothyronine (T3) stimulates insulin-like growth factor (IGF)-1 and IGF binding protein (IGFBP)-2 production by rat osteoblasts in vitro

1992 • 59 citations

Bone formation induced in an infant by systemic prostaglandin-E₂administration

1988 • 57 citations

Expression of insulin-like growth factor I messenger ribonucleic acid in regenerating bone after fracture: Influence of indomethacin

1992 • 56 citations

Local stimulation of new bone formation by prostaglandin E1: Quantitative histomorphometry and comparison of delivery by minipumps and controlled-release pellets

1993 • 55 citations

Effects of prostaglandins on regional remodeling changes during tibial healing in beagles: A histomorphometric study

1986 • 38 citations

Constitutive synthesis of insulin-like growth factor-II by primary osteoblast-enriched cultures from fetal rat calvariae.

1992 • 35 citations

The effects of prostaglandin E2 on DNA and collagen synthesis in osteoblastsIn Vitro

1989 • 33 citations

Prostaglandin E2 administered by subcutaneous pellets causes local inflammation and systemic bone loss: A model for inflammation-induced bone disease

1993 • 29 citations

Surface Modification of Polymers to Permit Endothelial Cell Growth

1991 • 21 citations

Stimulation of calcium uptake in rat calvaria by prostacyclin

1985 • 14 citations