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Excitatory amino acid neurotoxicity and neurodegenerative disease

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1988 • 1,745 citations

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

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1996 • 1,589 citations

The Role of Excitatory Amino Acids and NMDA Receptors in Traumatic Brain Injury

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Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1999 • 1,483 citations

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Molecular diversity of the NMDA receptor channel

1992 • 1,354 citations

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1995 • 1,239 citations

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p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

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1996 • 901 citations

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Deregulation of Cdk5 in a Mouse Model of ALS

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Global Ischemia Induces Downregulation of Glur2 mRNA and Increases AMPA Receptor-Mediated Ca²⁺Influx in Hippocampal CA1 Neurons of Gerbil

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Estrogen Protects against Global Ischemia-Induced Neuronal Death and Prevents Activation of Apoptotic Signaling Cascades in the Hippocampal CA1

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Cdk5-Mediated Inhibition of the Protective Effects of Transcription Factor MEF2 in Neurotoxicity-Induced Apoptosis

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Purification and characterization of a novel proline-directed protein kinase from bovine brain.

1992 • 238 citations

Expression of Inducible Nitric Oxide Synthase after Focal Cerebral Ischemia Stimulates Neurogenesis in the Adult Rodent Dentate Gyrus

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Interaction of Calcineurin and Type-A GABA Receptor γ₂Subunits Produces Long-Term Depression at CA1 Inhibitory Synapses

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Calpain Activity in the Rat Brain after Transient Forebrain Ischemia

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Calcium Uptake Evoked by Electrical Stimulation is Enhanced Postischemically and Precedes Delayed Neuronal Death in CA1 of Rat Hippocampus: Involvement of N-Methyl-D-Aspartate Receptors

1988 • 106 citations

AMPA receptor‐mediated toxicity in oligodendrocyte progenitors involves free radical generation and activation of JNK, calpain and caspase 3

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Glutamate receptor antagonists inhibit calpain-mediated cytoskeletal proteolysis in focal cerebral ischemia

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Postischemic Enhancements of N-Methyl-D-Aspartic Acid (NMDA) and Non-NMDA Receptor-Mediated Responses in Hippocampal CA1 Pyramidal Neurons

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Cyclin-dependent kinases and stroke

2001 • 10 citations