Neuroprotective Effect of an Antioxidant, Lutein, during Retinal Inflammation

Free radicals and antioxidants in normal physiological functions and human disease

2006 • 13,251 citations

A central role for inflammation in the pathogenesis of diabetic retinopathy

2004 • 1,105 citations

Oxidative damage–induced inflammation initiates age-related macular degeneration

2008 • 681 citations

Oxidative Stress and Diabetic Retinopathy

2007 • 673 citations

Contributions of Inflammatory Processes to the Development of the Early Stages of Diabetic Retinopathy

2007 • 599 citations

Activation of the JAK-STAT pathway by reactive oxygen species

1998 • 566 citations

Oxidative Stress and Autophagy

2006 • 506 citations

The Role of Inflammation in the Pathogenesis of Age-related Macular Degeneration

2006 • 481 citations

Ubiquitin Conjugation Is Not Required for the Degradation of Oxidized Proteins by Proteasome

2002 • 440 citations

The science behind lutein

2004 • 392 citations

Atherosclerosis and Oxidative Stress

2001 • 290 citations

Vascular endothelial growth factor and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives

2003 • 287 citations

Ciliary Neurotrophic Factor and Stress Stimuli Activate the Jak-STAT Pathway in Retinal Neurons and Glia

2000 • 259 citations

Oxidative Stress Triggers STAT3 Tyrosine Phosphorylation and Nuclear Translocation in Human Lymphocytes

1999 • 256 citations

The photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod versus cone genes

2005 • 246 citations

Reactive Oxygen Species Regulate Heat-Shock Protein 70 via the JAK/STAT Pathway

2001 • 214 citations

Production of Interleukin-6 by Skeletal Myotubes

2002 • 183 citations

Attenuated Glial Reactions and Photoreceptor Degeneration after Retinal Detachment in Mice Deficient in Glial Fibrillary Acidic Protein and Vimentin

2007 • 159 citations

Rhodopsin Signaling and Organization in Heterozygote Rhodopsin Knockout Mice

2004 • 155 citations

Macular Pigment Lutein Is Antiinflammatory in Preventing Choroidal Neovascularization

2007 • 150 citations

Pharmacological consequences of oxidative stress in ocular tissues

2005 • 143 citations

Interleukin-6 Receptor-Mediated Activation of Signal Transducer and Activator of Transcription-3 (STAT3) Promotes Choroidal Neovascularization

2007 • 142 citations

Angiotensin II Type 1 Receptor Signaling Contributes to Synaptophysin Degradation and Neuronal Dysfunction in the Diabetic Retina

2008 • 132 citations

Neuroprotective Effects of Angiotensin II Type 1 Receptor (AT1R) Blocker, Telmisartan, via Modulating AT1R and AT2R Signaling in Retinal Inflammation

2006 • 120 citations

Angiotensin II Type 1 Receptor–Mediated Inflammation Is Required for Choroidal Neovascularization

2006 • 118 citations

Inhibitory Effects of Lutein on Endotoxin-Induced Uveitis in Lewis Rats

2006 • 116 citations

Clinical implications of oxidative stress and antioxidant therapy

2005 • 109 citations

Ciliary Neurotrophic Factor Activates JAK/Stat Signal Transduction Cascade and Induces Transcriptional Expression of Glial Fibrillary Acidic Protein in Glial Cells

1997 • 106 citations

Alpha-lipoic acid treatment ameliorates metabolic parameters, blood pressure, vascular reactivity and morphology of vessels already damaged by streptozotocin-diabetes.

2000 • 95 citations

Regulation of Rod Phototransduction Machinery by Ciliary Neurotrophic Factor

2006 • 87 citations

Ubiquitinylation and Ubiquitin-dependent Proteolysis in Vertebrate Photoreceptors (Rod Outer Segments)

1996 • 83 citations

Suppression of Ocular Inflammation in Endotoxin-Induced Uveitis by Blocking the Angiotensin II Type 1 Receptor

2005 • 80 citations

Roles of STAT3/SOCS3 Pathway in Regulating the Visual Function and Ubiquitin-Proteasome-dependent Degradation of Rhodopsin during Retinal Inflammation

2008 • 79 citations

NF-κB: an important transcription factor in photobiology

1998 • 78 citations

[33] Distribution of macular pigment components, zeaxanthin and lutein, in human retina

1992 • 66 citations

Antirheumatoid Arthritis Effect ofRhus vernicifluaand of the Active Component, Sulfuretin

2003 • 51 citations

Expression of cytokine signal transduction components in the postnatal mouse retina.

2003 • 47 citations

Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina

2004 • 46 citations

Pressure-Induced Regulation of IL-6 in Retinal Glial Cells: Involvement of the Ubiquitin/Proteasome Pathway and NFκB

2006 • 42 citations

Herpes simplex virus type 1 alters transcript levels of tumor necrosis factor-alpha and interleukin-6 in retinal glial cells.

1996 • 36 citations

Nuclear factor-κB p65 and upregulation of interleukin-6 in retinal ischemia/reperfusion injury in rats

2006 • 28 citations

Lipid–protein modifications during ascorbate‐Fe²⁺ peroxidation of photoreceptor membranes: protective effect of melatonin

2006 • 27 citations

Visualizing Tubular Lipid Peroxidation in Intact Renal Tissue in Hypertensive Rats

2002 • 27 citations

SOCS3 is required to temporally fine-tune photoreceptor cell differentiation

2006 • 26 citations

Adrenomedullin as a Potent Antioxidative and Antiatherosclerotic Substance

2005 • 25 citations