CpG hypomethylation of MDR1 gene in tumor and serum of invasive ductal breast carcinoma patients

Cancer Statistics, 2008

2008 • 10,165 citations

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

1992 • 3,099 citations

Mechanisms of Cancer Drug Resistance

2002 • 2,495 citations

National Institutes of Health Consensus Development Conference Statement: Adjuvant Therapy for Breast Cancer, November 1-3, 2000

2001 • 888 citations

DNA methylation in serum of breast cancer patients: an independent prognostic marker.

2003 • 319 citations

ABC-transporters: implications on drug resistance from microorganisms to human cancers

2003 • 294 citations

Transcriptional Regulation of the MDR1 Gene by Histone Acetyltransferase and Deacetylase Is Mediated by NF-Y

1998 • 289 citations

ATP binding cassette transporters and drug resistance in breast cancer.

2003 • 255 citations

Tumor Suppressor Gene Promoter Hypermethylation in Serum of Breast Cancer Patients

2004 • 231 citations

Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs

2005 • 194 citations

Promoter Hypermethylation in Benign Breast Epithelium in Relation to Predicted Breast Cancer Risk

2005 • 186 citations

The Indian scene.

2001 • 183 citations

Evaluation of HER-2/neu Immunohistochemical Assay Sensitivity and Scoring on Formalin-Fixed and Paraffin-Processed Cell Lines and Breast Tumors

2002 • 177 citations

Precipitous Release of Methyl-CpG Binding Protein 2 and Histone Deacetylase 1 from the Methylated Human Multidrug Resistance Gene (MDR1) on Activation

2002 • 173 citations

Immunocytochemical estrogen and progestin receptor assays in breast cancer with monoclonal antibodies. Histopathologic, demographic, and biochemical correlations and relationship to endocrine response and survival

1990 • 171 citations

Hypomethylation Status of CpG Sites at the Promoter Region and Overexpression of the Human MDR1 Gene in Acute Myeloid Leukemias

1998 • 166 citations

Transcriptional regulators of the human multidrug resistance 1 gene: recent views

2002 • 164 citations

Clinico-morphological patterns of breast cancer including family history in a New Delhi hospital, India-A cross-sectional study

2005 • 147 citations

Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo

2009 • 145 citations

Altered methylation of the human MDR1 promoter is associated with acquired multidrug resistance.

1997 • 141 citations

Hypomethylation Status of CpG Sites at the Promoter Region and Overexpression of the Human MDR1 Gene in Acute Myeloid Leukemias

1998 • 133 citations

Promoter hypermethylation of TMS1, BRCA1, ERα and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients

2007 • 111 citations

Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients

2007 • 100 citations

Relationship between the expression of cyclooxygenase 2 and MDR1/P-glycoprotein in invasive breast cancers and their prognostic significance

2005 • 83 citations

Prognostic relevance of P-glycoprotein expression in breast cancer

1995 • 81 citations

CpG Hypermethylation of MDR1 Gene Contributes to the Pathogenesis and Progression of Human Prostate Cancer

2004 • 79 citations

Role of p-glycoprotein expression in predicting response to neoadjuvant chemotherapy in breast cancer-a prospective clinical study

2005 • 68 citations

Inhibitors of DNA methylation: beyond myelodysplastic syndromes

2005 • 67 citations

RNA expression of MDR1/P-glycoprotein, DNA-topoisomerase I, and MRP2 in ovarian carcinoma patients: correlation with chemotherapeutic response

2004 • 63 citations

Expression of multidrug resistance-associated protein1,P-glycoprotein, and thymidylate synthase in gastric cancer patients treated with 5-fluorouracil and doxorubicin-based adjuvant chemotherapy after curative resection

2002 • 61 citations

Predictive and prognostic markers for invasive breast cancer

2002 • 56 citations

Expression of LRP and MDR1 in locally advanced breast cancer predicts axillary node invasion at the time of rescue mastectomy after induction chemotherapy

2001 • 53 citations

Modulation of molecular marker expression by induction chemotherapy in locally advanced breast cancer: correlation with the response to therapy and the expression of MDR1 and LRP.

2001 • 51 citations

Expression of mediated P-glycoprotein multidrug resistance related to Tc-99m MIBI scintimammography results

2000 • 43 citations

Methylated NEUROD1 Promoter is a Marker for Chemosensitivity in Breast Cancer

2008 • 38 citations

5-aza-2'-deoxycytidine sensitizes hepatoma and pancreatic cancer cell lines

2005 • 29 citations

Silencing DNA Methyltransferase (DNMT) Enhances Glioma Chemosensitivity

2008 • 23 citations

Expression of MDR proteins in breast cancer and its correlation with some clinical and pathological parameters.

2006 • 18 citations