VDUP1 Is Required for the Development of Natural Killer Cells

Vitamin D

1979 • 3,814 citations

Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice

2000 • 1,578 citations

Host resistance directed selectively against H-2-deficient lymphoma variants. Analysis of the mechanism.

1985 • 734 citations

Identification of Thioredoxin-binding Protein-2/Vitamin D3 Up-regulated Protein 1 as a Negative Regulator of Thioredoxin Function and Expression

1999 • 696 citations

Selective Defects in the Development of the Fetal and Adult Lymphoid System in Mice with an Ikaros Null Mutation

1996 • 619 citations

Intraepithelial lymphocytes: exploring the Third Way in immunology

2001 • 481 citations

What does it take to make a natural killer?

2003 • 481 citations

Vitamin D3 Up-Regulated Protein 1 Mediates Oxidative Stress Via Suppressing the Thioredoxin Function

2000 • 480 citations

A potential role for interleukin-15 in the regulation of human natural killer cell survival.

1997 • 413 citations

Abnormal Development of Intestinal Intraepithelial Lymphocytes and Peripheral Natural Killer Cells in Mice Lacking the IL-2 Receptor β Chain

1997 • 359 citations

Requirement for IRF-1 in the microenvironment supporting development of natural killer cells

1998 • 352 citations

Induction of tumor-specific T cell memory by NK cell–mediated tumor rejection

2001 • 349 citations

What is a natural killer cell?

2002 • 339 citations

Interleukin 15 Controls both Proliferation and Survival of a Subset of Memory-Phenotype CD8+ T Cells

2002 • 332 citations

Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3

1994 • 313 citations

Regional specialization in the mucosal immune system: primed cells do not always home along the same track

1999 • 287 citations

VDUP1 upregulated by TGF-β1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression

2003 • 269 citations

Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage

1999 • 259 citations

Natural killer cell activation in mice and men: different triggers for similar weapons?

2002 • 204 citations

2B4 Acts As a Non–Major Histocompatibility Complex Binding Inhibitory Receptor on Mouse Natural Killer Cells

2004 • 201 citations

Commitment to natural killer cells requires the helix–loop–helix inhibitor Id2

2001 • 168 citations

Natural killer cell dysfunction and apoptosis induced by chronic myelogenous leukemia cells: role of reactive oxygen species and regulation by histamine

2000 • 167 citations

Signaling via LTβR on the lamina propria stromal cells of the gut is required for IgA production

2002 • 152 citations

Requirement of Hydrogen Peroxide Generation in TGF-β1 Signal Transduction in Human Lung Fibroblast Cells: Involvement of Hydrogen Peroxide and Ca2+ in TGF-β1-Induced IL-6 Expression

2000 • 145 citations

Requirement for membrane lymphotoxin in natural killer cell development

1999 • 137 citations

The effects of 1,25-dihydroxyvitamin D3 on human T lymphocyte activation and proliferation: a cell cycle analysis.

1985 • 137 citations

Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells

2001 • 130 citations

Loss of Thioredoxin-Binding Protein-2/Vitamin D3 Up-Regulated Protein 1 in Human T-Cell Leukemia Virus Type I-Dependent T-Cell Transformation

2004 • 126 citations

Differentiation of NK1.1+, Ly49+ NK cells from flt3+ multipotent marrow progenitor cells.

1999 • 124 citations

Differentiation of NK1.1+, Ly49+ NK Cells from flt3+ Multipotent Marrow Progenitor Cells

1999 • 106 citations

Regulatory function for murine intraepithelial lymphocytes. Two subsets of CD3+, T cell receptor-1+ intraepithelial lymphocyte T cells abrogate oral tolerance.

1990 • 90 citations

The Immediate-Early Gene Product Egr-1 Regulates the Human Interleukin-2 Receptor β-Chain Promoter through Noncanonical Egr and Sp1 Binding Sites

1997 • 86 citations

Vitamin D, thyroid hormones and muscle mass influence natural killer (NK) innate immunity in healthy nonagenarians and centenarians

1999 • 86 citations

Development and tolerance of natural killer cells

1999 • 85 citations

Natural killer cell cytotoxicity in the peripheral blood, cervical lymph nodes, and tumor of head and neck cancer patients.

1988 • 84 citations

Murine natural killer cell progenitors and their requirements for development

2002 • 60 citations

Antagonistic effect of NK cells on alternatively activated monocytes: a contribution of NK cells to CTL generation

2002 • 50 citations

Relationship between cell cycle molecules and onset of oligodendrocyte differentiation

2003 • 48 citations

IL-2Rbeta/IL-7Ralpha doubly deficient mice recapitulate the thymic and intraepithelial lymphocyte (IEL) developmental defects of gammac-/- mice: roles for both IL-2 and IL-15 in CD8alphaalpha IEL development.

1999 • 47 citations

Induction of the interleukin-2/15 receptor β-chain by the EWS–WT1 translocation product

2002 • 45 citations

Susceptibility of Natural Killer (NK) Cells to Reactive Oxygen Species (ROS) and Their Restoration by the Mimics of Superoxide Dismutase (SOD)

1998 • 45 citations

Lymphocyte commitment during embryonic development, in the mouse

2002 • 43 citations

Effect of 1,25(OH)2-Vitamin D3 on the Activation of Natural Killer Cells: Role of Protein Kinase C and Extracellular Calcium

1999 • 42 citations

IL-2Rβ/IL-7Rα Doubly Deficient Mice Recapitulate the Thymic and Intraepithelial Lymphocyte (IEL) Developmental Defects of γc−/− Mice: Roles for Both IL-2 and IL-15 in CD8αα IEL Development

1999 • 40 citations

Vitamin D3 up-regulating protein 1 (VDUP1) antisense DNA regulates tumorigenicity and melanogenesis of murine melanoma cells via regulating the expression of fas ligand and reactive oxygen species

2003 • 39 citations

Transforming growth factor type beta 1 (TGF‐β1) down‐regulates interleukin‐2 production and up‐regulates interleukin‐2 receptor expression in a thymoma cell line

1991 • 22 citations

1,25-Dihydroxyvitamin-D3 regulation of interleukin-2 and interleukin-2 receptor levels and gene expression in human T cells

1989 • 21 citations

Differentiation induction of HL60 cells by 1,25(OH)2D3, all trans retinoic acid, rTGF-β2 and their combinations

1997 • 18 citations

Suppression of natural killer and lymphocyte functions associated with carcinogen-induced premalignant hyperplastic nodules in rat liver.

1985 • 13 citations

Hyperplasia of mouse duodenal crypts and its control by NK cells during the initial phase of DMH carcinogenesis

1990 • 9 citations