Oligoclonal repertoire of the CD8 alpha alpha and the CD8 alpha beta TCR-alpha/beta murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells.

MICROBIAL ECOLOGY OF THE GASTROINTESTINAL TRACT

1977 • 2,394 citations

The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments.

1993 • 664 citations

Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation.

1991 • 599 citations

A monoclonal antibody (HML‐1) defining a novel membrane molecule present on human intestinal lymphocytes

1987 • 461 citations

The mouse gut T lymphocyte, a novel type of T cell. Nature, origin, and traffic in mice in normal and graft-versus-host conditions.

1978 • 422 citations

Intestinal intraepithelial lymphocytes are a distinct set of γδ T cells

1988 • 394 citations

Optimal conditions for directly sequencing double-stranded PCR products with Sequenase

1990 • 357 citations

The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation.

1991 • 345 citations

Localization of gamma/delta T cells to the intestinal epithelium is independent of normal microbial colonization.

1990 • 281 citations

Thymus-independent development and negative selection of T cells expressing T cell receptor alpha/beta in the intestinal epithelium: evidence for distinct circulation patterns of gut- and thymus-derived T lymphocytes.

1992 • 268 citations

Extrathymic origin of intestinal intraepithelial lymphocytes bearing T-cell antigen receptor gamma delta.

1991 • 262 citations

Oligoclonal Expansion and CD1 Recognition by Human Intestinal Intraepithelial Lymphocytes

1991 • 243 citations

Diversity of γδ T-cell receptors on murine intestinal intraepithelial lymphocytes

1989 • 217 citations

Increased Frequency of N-Region Insertion in a Murine Pre-B-Cell Line Infected with a Terminal Deoxynucleotidyl Transferase Retroviral Expression Vector

1987 • 214 citations

Thymic and extrathymic origins of gut intraepithelial lymphocyte populations in mice.

1994 • 208 citations

Molecular detection and in vivo analysis of the specific T cell response to a protein antigen

1992 • 176 citations

Human intestinal intraepithelial lymphocytes are derived from a limited number of T cell clones that utilize multiple V beta T cell receptor genes.

1993 • 174 citations

Selection of intraepithelial lymphocytes with CD8 alpha/alpha co-receptors by self-antigen in the murine gut.

1992 • 163 citations

Most gamma delta T cells develop normally in beta 2-microglobulin-deficient mice.

1992 • 147 citations

Fate of H2-activated T lymphocytes in syngeneic hosts

1976 • 147 citations

Gut injury in mouse graft-versus-host reaction. Study of its occurrence and mechanisms.

1986 • 135 citations

Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation.

1994 • 120 citations

Phenotype of intraepithelial lymphocytes in euthymic and athymic mice: Implications for differentiation of cells bearing a CD3‐associated γδ T cell receptor

1990 • 116 citations

The V beta 17+ T cell repertoire: skewed J beta usage after thymic selection; dissimilar CDR3s in CD4+ versus CD8+ cells.

1991 • 109 citations

Different expression of the recombination activity gene RAG‐1 in various populations of thymocytes, peripheral T cells and gut thymus‐independent intraepithelial lymphocytes suggests two pathways of T cell receptor rearrangement

1992 • 107 citations

Peripheral engraftment of fetal intestine into athymic mice sponsors T cell development: direct evidence for thymopoietic function of murine small intestine.

1992 • 97 citations

THE HOMING OF LYMPH-BORNE IMMUNOBLASTS TO THE SMALL GUT OF NEONATAL RATS

1972 • 88 citations

Thymus influences the development of extrathymically derived intestinal intraepithelial lymphocytes

1993 • 86 citations

Influence of Viral Superantigens on Vβ‐and Vα Specific Positive and Negative Selection

1993 • 83 citations

Thymus-independent positive and negative selection of T cells expressing a major histocompatibility complex class I restricted transgenic T cell receptor alpha/beta in the intestinal epithelium.

1993 • 80 citations

Rearrangement and junctional-site sequence analyses of T-cell receptor gamma genes in intestinal intraepithelial lymphocytes from murine athymic chimeras.

1991 • 34 citations

Analysis of intraepithelial lymphocytes from major histocompatibility complex (MHC)‐deficient mice: No evidence for a role of MHC class II antigens in the positive selection of Vδ4⁺γδ T cells

1993 • 29 citations

Rearrangement and Junctional-Site Sequence Analyses of T-Cell Receptor Gamma Genes in Intestinal Intraepithelial Lymphocytes from Murine Athymic Chimeras

1991 • 8 citations