Activation of Erk1/Erk2 and transiently increased p53 levels together may account for p21 expression associated with phorbol ester-induced transient growth inhibition in HepG2 cells

Integrin Signaling

1999 • 3,705 citations

Activation of the Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Pathway by Conventional, Novel, and Atypical Protein Kinase C Isotypes

1998 • 765 citations

Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21^Cip1

1997 • 643 citations

High-Intensity Raf Signal Causes Cell Cycle Arrest Mediated by p21^Cip1

1997 • 464 citations

Integrating the MAP kinase signal into the G1 phase cell cycle machinery

2000 • 458 citations

Endothelin-1 Is Involved in Mechanical Stress-induced Cardiomyocyte Hypertrophy

1996 • 400 citations

Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

1998 • 348 citations

The protein kinase C inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase‐1β (Rsk‐2) and p70 S6 kinase

1997 • 206 citations

Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway.

1996 • 200 citations

p300 Collaborates with Sp1 and Sp3 in p21 / Promoter Activation Induced by Histone Deacetylase Inhibitor

2000 • 169 citations

The MEK Pathway Is Required for Stimulation of p21WAF1/CIP1 by Transforming Growth Factor-β

1999 • 160 citations

Strategies for manipulating the p53 pathway in the treatment of human cancer

2000 • 142 citations

Regulation and function of the p53-related proteins: same family, different rules

2000 • 123 citations

Phosphatidylinositol 3-kinase Contributes to Erk1/Erk2 MAP Kinase Activation Associated with Hepatocyte Growth Factor-induced Cell Scattering

1999 • 71 citations

The extracellular matrix and mitogenic growth factors control G1 phase cyclins and cyclin-dependent kinase inhibitors

1997 • 64 citations

Induction of p21WAF1 expression via Sp1-binding sites by tamoxifen in estrogen receptor-negative lung cancer cells

2000 • 62 citations

Demystified ... cell cycle

1998 • 46 citations

Partial down‐regulation of protein kinase C reverses the growth inhibitory effect of phorbol esters on HepG2 cells

1990 • 44 citations

The Role of the Smad3 Protein in Phorbol Ester-induced Promoter Expression

1999 • 31 citations

Possible involvement of p21/waf1 in the growth inhibition of HepG2 cells induced by hepatocyte growth factor

1998 • 25 citations

Protein kinase C decreases the hepatocyte growth factor-induced activation of Erk1/Erk2 MAP kinases

2000 • 12 citations