RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo

Rho GTPases in cell biology

2002 • 4,662 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

Activation of Rac and Cdc42 by Integrins Mediates Cell Spreading

1998 • 638 citations

Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases

1998 • 615 citations

Unconventional Rac-GEF activity is mediated through the Dock180–ELMO complex

2002 • 569 citations

CED-12/ELMO, a Novel Member of the CrkII/Dock180/Rac Pathway, Is Required for Phagocytosis and Cell Migration

2001 • 558 citations

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

1998 • 426 citations

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

2002 • 405 citations

Rhotekin, a New Putative Target for Rho Bearing Homology to a Serine/Threonine Kinase, PKN, and Rhophilin in the Rho-binding Domain

1996 • 378 citations

αvβ5 integrin recruits the CrkII–Dock180–Rac1 complex for phagocytosis of apoptotic cells

2000 • 375 citations

DOCK180, a Major CRK-Binding Protein, Alters Cell Morphology upon Translocation to the Cell Membrane

1996 • 339 citations

UNC-73 Activates the Rac GTPase and Is Required for Cell and Growth Cone Migrations in C. elegans

1998 • 319 citations

ThreeC. elegansRac proteins and several alternative Rac regulators control axon guidance, cell migration and apoptotic cell phagocytosis

2001 • 244 citations

Evidence That DOCK180 Up-regulates Signals from the CrkII-p130Cas Complex

1998 • 207 citations

Laminin-10/11 and Fibronectin Differentially Regulate Integrin- dependent Rho and Rac Activation via p130Cas-CrkII-DOCK180 Pathway

2001 • 171 citations

TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of RhoG

2000 • 166 citations

C. elegans CED-12 Acts in the Conserved CrkII/DOCK180/Rac Pathway to Control Cell Migration and Cell Corpse Engulfment

2001 • 165 citations

RhoG GTPase Controls a Pathway That Independently Activates Rac1 and Cdc42Hs

1998 • 162 citations

The Human Rho-GEF Trio and Its Target GTPase RhoG Are Involved in the NGF Pathway, Leading to Neurite Outgrowth

2002 • 152 citations

Small GTPase RhoG Is a Key Regulator for Neurite Outgrowth in PC12 Cells

2000 • 138 citations

Kalirin Dbl-Homology Guanine Nucleotide Exchange Factor 1 Domain Initiates New Axon Outgrowths via RhoG-Mediated Mechanisms

2002 • 88 citations

Socius Is a Novel Rnd GTPase-Interacting Protein Involved in Disassembly of Actin Stress Fibers

2002 • 75 citations

Distinct Rac Activation Pathways Control Caenorhabditis elegans Cell Migration and Axon Outgrowth

2002 • 71 citations

RhoG regulates gene expression and the actin cytoskeleton in lymphocytes

2003 • 48 citations