Treatment of Chlamydia trachomatis with a small molecule inhibitor of the Yersinia type III secretion system disrupts progression of the chlamydial developmental cycle

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

2007 • 11,720 citations

Type III Protein Secretion Systems in Bacterial Pathogens of Animals and Plants

1998 • 2,394 citations

Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis

1998 • 1,548 citations

Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis

1981 • 1,054 citations

Interaction of chlamydiae and host cells in vitro

1991 • 734 citations

Complete genome sequence of the Q-fever pathogenCoxiellaburnetii

2003 • 533 citations

Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis

2003 • 491 citations

Chlamydial Persistence: beyond the Biphasic Paradigm

2004 • 453 citations

A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin

2004 • 397 citations

Differential interaction with endocytic and exocytic pathways distinguish parasitophorous vacuoles of Coxiella burnetii and Chlamydia trachomatis

1996 • 394 citations

Chlamydia trachomatis interrupts an exocytic pathway to acquire endogenously synthesized sphingomyelin in transit from the Golgi apparatus to the plasma membrane.

1996 • 387 citations

Identification of a Chlamydial Protease–Like Activity Factor Responsible for the Degradation of Host Transcription Factors

2001 • 378 citations

Compartmentalization of Gene Expression duringBacillus subtilisSpore Formation

2004 • 354 citations

Lipid metabolism in Chlamydia trachomatis-infected cells: directed trafficking of Golgi-derived sphingolipids to the chlamydial inclusion.

1995 • 348 citations

Interaction of chlamydiae and host cells in vitro.

1991 • 327 citations

Secretion of YscP from Yersinia enterocolitica is essential to control the length of the injectisome needle but not to change the type III secretion substrate specificity

2005 • 304 citations

Temporal Analysis of Coxiella burnetii Morphological Differentiation

2004 • 281 citations

Three temporal classes of gene expression during the Chlamydia trachomatis developmental cycle

2000 • 269 citations

The Chlamydia trachomatis IncA protein is required for homotypic vesicle fusion

1999 • 225 citations

Targeting Bacterial Virulence

2003 • 224 citations

The Chlamydial Inclusion: Escape from the Endocytic Pathway

2002 • 215 citations

Small-Molecule Inhibitors Specifically Targeting Type III Secretion

2005 • 213 citations

Type III secretion genes identify a putative virulence locus of Chlamydia

1997 • 187 citations

Proteins in the chlamydial inclusion membrane

2002 • 185 citations

Chlamydia trachomatis uses host cell dynein to traffic to the microtubule-organizing center in a p50 dynamitin-independent process

2003 • 181 citations

Chlamydia trachomatis type III secretion: evidence for a functional apparatus during early‐cycle development

2003 • 180 citations

Vesicular interactions of the Chlamydia trachomatis inclusion are determined by chlamydial early protein synthesis rather than route of entry

1996 • 176 citations

Identification and characterization of a Chlamydia trachomatis early operon encoding four novel inclusion membrane proteins

1999 • 172 citations

Secretion of predicted Inc proteins of Chlamydia pneumoniae by a heterologous type III machinery

2001 • 168 citations

Evidence for the secretion of Chlamydia trachomatis CopN by a type III secretion mechanism

2000 • 163 citations

Restricted Fusion of Chlamydia trachomatis Vesicles with Endocytic Compartments during the Initial Stages of Infection

2003 • 158 citations

Isolates ofChlamydia trachomatisThat Occupy Nonfusogenic Inclusions Lack IncA, a Protein Localized to the Inclusion Membrane

2000 • 152 citations

A directed screen for chlamydial proteins secreted by a type III mechanism identifies a translocated protein and numerous other new candidates

2005 • 134 citations

The Titration of Trachoma and Inclusion Blennorrhoea Viruses in Cell Cultures

1960 • 126 citations

A series of fluorescent N-acylsphingosines: synthesis, physical properties, and studies in cultured cells

1988 • 124 citations

Chlamydia trachomatis persistence: An update

2005 • 119 citations

Chlamydia trachomatis utilizes the host cell microtubule network during early events of infection

1997 • 115 citations

Chlamydia trachomatis Infection of Epithelial Cells Induces the Activation of Caspase-1 and Release of Mature IL-18

2000 • 107 citations

CADD, a Chlamydia Protein That Interacts with Death Receptors

2002 • 100 citations

Selection and characterization of Yersinia pestis YopN mutants that constitutively block Yop secretion

2005 • 99 citations

Regulation of type III secretion in Bordetella

2004 • 86 citations

Monoclonal antibodies define genus-specific, species-specific, and cross-reactive epitopes of the chlamydial 60-kilodalton heat shock protein (hsp60): specific immunodetection and purification of chlamydial hsp60

1992 • 81 citations

The diverse habitats of obligate intracellular parasites

1998 • 80 citations

Analysis of PutativeChlamydia trachomatisChaperones Scc2 and Scc3 and Their Use in the Identification of Type III Secretion Substrates

2005 • 78 citations

A small RNA inhibits translation of the histone‐like protein Hc1 in Chlamydia trachomatis

2005 • 76 citations

Chlamydial histone-DNA interactions are disrupted by a metabolite in the methylerythritol phosphate pathway of isoprenoid biosynthesis

2004 • 70 citations

Expression and translocation of chlamydial protease during acute and persistent infection of the epithelial HEp-2 cells with Chlamydophila (Chlamydia) pneumoniae

2003 • 65 citations

A Developmentally Regulated Two-component Signal Transduction System in Chlamydia

2003 • 52 citations

New view of the surface projections of Chlamydia trachomatis

1985 • 48 citations

Interactions between Partner Switcher Orthologs BtrW and BtrV Regulate Type III Secretion in Bordetella

2005 • 48 citations

Expression of the transcripts of the sigma factors and putative sigma factor regulators of Chlamydia trachomatis L2

2000 • 46 citations

Core of the partner switching signalling mechanism is conserved in the obligate intracellular pathogen Chlamydia trachomatis

2005 • 30 citations

Electron Microscopic Observations of Surface Projections and Related Intracellular Structures of <italic>Chlamydia</italic> Organisms

1981 • 29 citations