Determination of the Functional Epitopes of Human Interleukin-18-binding Protein by Site-directed Mutagenesis

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

A Hot Spot of Binding Energy in a Hormone-Receptor Interface

1995 • 1,943 citations

Anatomy of hot spots in protein interfaces

1998 • 1,908 citations

[31] PHD: Predicting one-dimensional protein structure by profile-based neural networks

1996 • 1,291 citations

Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

1997 • 1,172 citations

Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme

1997 • 1,137 citations

IL-18: A TH1 -inducing, proinflammatory cytokine and new member of the IL-1 family

1999 • 806 citations

Interleukin-18 Binding Protein

1999 • 759 citations

IGIF Does Not Drive Th1 Development but Synergizes with IL-12 for Interferon-γ Production and Activates IRAK and NFκB

1997 • 726 citations

A minimal peptide substrate in biotin holoenzyme synthetase‐catalyzed biotinylation

1999 • 702 citations

Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein.

1996 • 635 citations

Purification and Characterization of the Human Interleukin-18 Receptor

1997 • 471 citations

Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18

2000 • 335 citations

Cloning of a Novel Receptor Subunit, AcPL, Required for Interleukin-18 Signaling

1998 • 326 citations

Endotoxin-induced serum factor that stimulates gamma interferon production

1989 • 285 citations

Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1β

1997 • 258 citations

IL-1Rrp Is a Novel Receptor-like Molecule Similar to the Type I Interleukin-1 Receptor and Its Homologues T1/ST2 and IL-1R AcP

1996 • 225 citations

Epitope Mapping by Label-Free Biomolecular Interaction Analysis

1996 • 223 citations

IL-18 binding and inhibition of interferon γ induction by human poxvirus-encoded proteins

1999 • 197 citations

Pathophysiological roles of interleukin-18 in inflammatory liver diseases

2000 • 196 citations

Interleukin 18: a pleiotropic participant in chronic inflammation

2000 • 190 citations

Ectromelia, vaccinia and cowpox viruses encode secreted interleukin-18-binding proteins

2000 • 186 citations

A Poxvirus Protein That Binds to and Inactivates IL-18, and Inhibits NK Cell Response

2000 • 175 citations

Interleukin-18 Activates the IRAK-TRAF6 Pathway in Mouse EL-4 Cells

1998 • 138 citations

Cloning and expression of interleukin‐18 binding protein

1999 • 122 citations

Interleukin-1 Receptor Cluster: Gene Organization ofIL1R2, IL1R1, IL1RL2(IL-1Rrp2),IL1RL1(T1/ST2), andIL18R1(IL-1Rrp) on Human Chromosome 2q

1999 • 104 citations

Conservation of cys–cys trp structural triads and their geometry in the protein domains of immunoglobulin superfamily members

1999 • 73 citations

Orthopoxvirus IL-18 Binding Proteins: Affinities and Antagonist Activities

2001 • 69 citations

Identification of Human and Mouse Homologs of the MC51L–53L–54L Family of Secreted Glycoproteins Encoded by the Molluscum Contagiosum Poxvirus

1999 • 50 citations