Applications of Major Histocompatibility Complex Class I Molecules Expressed as Single Chains

Papillomaviruses and cancer: from basic studies to clinical application

2002 • 3,873 citations

T cell receptor antagonist peptides induce positive selection

1994 • 2,818 citations

MECHANISMS OF MHC CLASS I–RESTRICTED ANTIGEN PROCESSING

1998 • 1,017 citations

Herpes simplex virus turns off the TAP to evade host immunity

1995 • 736 citations

Localization, Quantitation, and In Situ Detection of Specific Peptide–MHC Class I Complexes Using a Monoclonal Antibody

1997 • 679 citations

A viral inhibitor of peptide transporters for antigen presentation

1995 • 599 citations

A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes

1994 • 553 citations

Gene vaccination with naked plasmid DNA: mechanism of CTL priming.

1996 • 494 citations

The ER-Luminal Domain of the HCMV Glycoprotein US6 Inhibits Peptide Translocation by TAP

1997 • 472 citations

Optimization of the MHC Class I Peptide Cargo Is Dependent on Tapasin

2002 • 349 citations

Brefeldin A Specifically Inhibits Presentation of Protein Antigens to Cytotoxic T Lymphocytes

1989 • 329 citations

Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation

1989 • 317 citations

A Viral ER-Resident Glycoprotein Inactivates the MHC-Encoded Peptide Transporter

1997 • 314 citations

Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer.

1996 • 305 citations

The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation

1997 • 274 citations

Inhibition of MHC class I-restricted antigen presentation by γ2-herpesviruses

2000 • 214 citations

MHC Class I Ubiquitination by a Viral PHD/LAP Finger Protein

2001 • 199 citations

Augmentation and Suppression of Immune Responses to an HIV-1 DNA Vaccine by Plasmid Cytokine/Ig Administration

1998 • 150 citations

Human Cytomegalovirus Inhibits Tapasin-Dependent Peptide Loading and Optimization of the MHC Class I Peptide Cargo for Immune Evasion

2004 • 142 citations

Virus Subversion of the MHC Class I Peptide-Loading Complex

2003 • 125 citations

Cutting Edge: Single-Chain Trimers of MHC Class I Molecules Form Stable Structures That Potently Stimulate Antigen-Specific T Cells and B Cells

2002 • 119 citations

Development of a DNA Vaccine Targeting Human Papillomavirus Type 16 Oncoprotein E6

2004 • 118 citations

Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes.

1991 • 117 citations

Viral Degradation of the MHC Class I Peptide Loading Complex

2004 • 101 citations

Tapasin: an ER chaperone that controls MHC class I assembly with peptide

2001 • 97 citations

Virus Evasion of MHC Class I Molecule Presentation

2003 • 94 citations

Direct visualization of distinct T cell epitopes derived from a melanoma tumor-associated antigen by using human recombinant antibodies with MHC- restricted T cell receptor-like specificity

2002 • 91 citations

Cancer immunotherapy using a DNA vaccine encoding a single-chain trimer of MHC class I linked to an HPV-16 E6 immunodominant CTL epitope

2005 • 77 citations

Cells expressing a major histocompatibility complex class I molecule with a single covalently bound peptide are highly immunogenic.

1995 • 70 citations

Differential thymic selection outcomes stimulated by focal structural alteration in peptide/major histocompatibility complex ligands

1998 • 61 citations

Enhanced Immune Presentation of a Single-chain Major Histocompatibility Complex Class I Molecule Engineered to Optimize Linkage of a C-terminally Extended Peptide

2003 • 60 citations

Model for the Interaction of Gammaherpesvirus 68 RING-CH Finger Protein mK3 with Major Histocompatibility Complex Class I and the Peptide-Loading Complex

2004 • 51 citations

Recognition of HLA-A2-restricted mammaglobin-A-derived epitopes

2004 • 48 citations

Peptide–β2-microglobulin–MHC fusion molecules bind antigen-specific T cells and can be used for multivalent MHC–Ig complexes

2002 • 45 citations

Physical Association of the K3 Protein of Gamma-2 Herpesvirus 68 with Major Histocompatibility Complex Class I Molecules with Impaired Peptide and β₂-Microglobulin Assembly

2002 • 42 citations

Creating HIV-1 reverse transcriptase cytotoxic T lymphocyte target structures by HLA-A2 heavy chain modifications

2000 • 8 citations