Immune processing of proteolipid protein by subsets of antigen-presenting spleen cells

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

MYELINATION IN RAT BRAIN: METHOD OF MYELIN ISOLATION¹

1973 • 1,412 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Antigen-Presenting Function of the Macrophage

1984 • 1,164 citations

Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing.

1983 • 701 citations

T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination

1985 • 522 citations

Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment

1990 • 377 citations

Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice.

1989 • 372 citations

Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations.

1991 • 355 citations

Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice

1984 • 311 citations

Monoclonal antibodies to murine gamma-interferon which differentially modulate macrophage activation and antiviral activity.

1985 • 286 citations

Macrophage endosomes contain proteases which degrade endocytosed protein ligands.

1985 • 223 citations

T helper cell subsets require the expression of distinct costimulatory signals by antigen-presenting cells.

1988 • 212 citations

Antigen conformation determines processing requirements for T-cell activation.

1984 • 181 citations

Characterization of a major encephalitogenic T cell epitope in SJL/J mice with synthetic oligopeptides of myelin basic protein

1988 • 154 citations

Two minor determinants of myelin basic protein induce experimental allergic encephalomyelitis in SJL/J mice.

1988 • 146 citations

Antigen presentation by splenic B cells: resting B cells are ineffective, whereas activated B cells are effective accessory cells for T cell responses.

1985 • 145 citations

Antigen processing at the molecular level

1987 • 137 citations

Immunotherapy of multiple sclerosis

1988 • 113 citations

Freshly isolated spleen dendritic cells and epidermal Langerhans cells undergo similar phenotypic and functional changes during short-term culture.

1990 • 90 citations

The molecular basis of the requirement for antigen processing of pigeon cytochrome c prior to T cell activation.

1985 • 89 citations

Mutations of class II MHC molecules

1987 • 85 citations

T-cell recognition of antigen and the Ia molecule as a ternary complex

1986 • 85 citations

Selective inhibition of antigen presentation to cloned T cells by protease inhibitors

1989 • 84 citations

Antigen recognition by T cells and B cells: Recognition of cross-reactivity between native and denatured forms of globular antigens

1980 • 83 citations

Presentation of antigen by B cells: functional dependence on radiation dose, interleukins, cellular activation, and differential glycosylation.

1985 • 78 citations

Antigen presentation by resting B cells. Effectiveness at inducing T cell proliferation is determined by costimulatory signals, not T cell receptor occupancy.

1990 • 66 citations

Processing of tetanus toxin by human antigen-presenting cells. Evidence for donor and epitope-specific processing pathways.

1989 • 62 citations

The adoptive transfer of chronic relapsing experimental allergic encephalomyelitis with lymph node cells sensitized to myelin proteolipid protein

1989 • 55 citations

Chronic relapsing experimental allergic encephalomyelitis in SJL mice following the adoptive transfer of an epitope-specific T cell line

1989 • 38 citations

The development and characterization of encephalitogenic cloned T cells specific for myelin proteolipid protein

1990 • 35 citations

Localization of an enciphalitogenic epitope for the SJL mouse in the N-terminal region of myelin basic protein

1990 • 27 citations

Antigen conformation determines processing requirements for T-cell activation

1985 • 22 citations

Antigen processing of myelin basic protein is required prior to recognition by T cells inducing EAE

1990 • 18 citations

Comparison of antigen specificity, class II major histocompatibility complex restriction, and in vivo behavior of myelin basic protein-specific T cell lines and clones derived from (BALB/c x SJL/J) mice.

1987 • 16 citations

Myelin Basic Protein-Specific T Cell Clones and Experimental Allergic Encephalomyelitis

1986 • 10 citations